Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model

por An, Yu A., Xiong, Wei, Chen, Shiuhwei, Bu, Dawei, Rutkowski, Joseph M., Berger, Joel P., Kusminski, Christine M., Zhang, Ningyan, An, Zhiqiang, Scherer, Philipp E.
Publicado 2023

De novo adipocyte differentiation from Pdgfrβ(+) preadipocytes protects against pathologic visceral adipose expansion in obesity

por Shao, Mengle, Vishvanath, Lavanya, Busbuso, Napoleon C., Hepler, Chelsea, Shan, Bo, Sharma, Ankit X., Chen, Shiuhwei, Yu, Xinxin, An, Yu A., Zhu, Yi, Holland, William L., Gupta, Rana K.
Publicado 2018

In Vivo ZIMIR Imaging of Mouse Pancreatic Islet Cells Shows Oscillatory Insulin Secretion

por Chen, Shiuhwei, Huang, ZhiJiang, Kidd, Harrison, Kim, Min, Suh, Eul Hyun, Xie, Shangkui, Ghazvini Zadeh, Ebrahim H., Xu, Yan, Sherry, A. Dean, Scherer, Philipp E., Li, Wen-hong
Publicado 2021

Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity

por An, Yu A., Crewe, Clair, Asterholm, Ingrid Wernstedt, Sun, Kai, Chen, Shiuhwei, Zhang, Fang, Shao, Mengle, Funcke, Jan-Bernd, Zhang, Zhuzhen, Straub, Leon, Klein, Samuel, Kusminski, Christine M., Scherer, Philipp E.
Publicado 2019

GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model

por de Souza, Camila O., Paschoal, Vivian A., Sun, Xuenan, Vishvanath, Lavanya, Zhang, Qianbin, Shao, Mengle, Onodera, Toshiharu, Chen, Shiuhwei, Joffin, Nolwenn, Bueno, Lorena M.A., Gupta, Rana K., Oh, Da Young
Publicado 2022

MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk

por Kusminski, Christine M., Chen, Shiuhwei, Ye, Risheng, Sun, Kai, Wang, Qiong A., Spurgin, Stephen B., Sanders, Phillip E., Brozinick, Joseph T., Geldenhuys, Werner J., Li, Wen-hong, Unger, Roger H., Scherer, Philipp E.
Publicado 2016

Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells

por Onodera, Toshiharu, Kim, Dae-Seok, Ye, Risheng, Wang, May-Yun, Chen, Shiuhwei, Field, Bianca C., Straub, Leon, Sun, Xue-Nan, Li, Chao, Lee, Charlotte, Paredes, Megan, Crewe, Clair, Zhao, Shangang, Kusminski, Christine M., Gordillo, Ruth, Scherer, Philipp E.
Publicado 2023

Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice

por Sharma, Ankit X., Quittner-Strom, Ezekiel B., Lee, Young, Johnson, Joshua A., Martin, Sarah A., Yu, Xinxin, Li, Jianping, Lu, John, Cai, Zheqing, Chen, Shiuhwei, Wang, May-yun, Zhang, Yiyi, Pearson, Mackenzie J., Dorn, Andie C., McDonald, Jeffrey G., Gordillo, Ruth, Yan, Hai, Thai, Dung, Wang, Zhao V., Unger, Roger H., Holland, William L.
Publicado 2018

Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization

por Onodera, Toshiharu, Wang, May-Yun, Rutkowski, Joseph M., Deja, Stanislaw, Chen, Shiuhwei, Balzer, Michael S., Kim, Dae-Seok, Sun, Xuenan, An, Yu A., Field, Bianca C., Lee, Charlotte, Matsuo, Ei-ichi, Mizerska, Monika, Sanjana, Ina, Fujiwara, Naoto, Kusminski, Christine M., Gordillo, Ruth, Gautron, Laurent, Marciano, Denise K., Hu, Ming Chang, Burgess, Shawn C., Susztak, Katalin, Moe, Orson W., Scherer, Philipp E.
Publicado 2023

Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets

por Wang, May-Yun, Dean, E. Danielle, Quittner-Strom, Ezekiel, Zhu, Yi, Chowdhury, Kamrul H., Zhang, Zhuzhen, Zhao, Shangang, Li, Na, Ye, Reshing, Lee, Young, Zhang, Yiyi, Chen, Shiuhwei, Yu, Xinxin, Leonard, Derek C., Poffenberger, Greg, Von Deylen, Alison, McCorkle, S. Kay, Schlegel, Amnon, Sloop, Kyle W., Efanov, Alexander M., Gimeno, Ruth E., Scherer, Philipp E., Powers, Alvin C., Unger, Roger H., Holland, William L.
Publicado 2021