From the groin to the brain: a transfemoral path to blood-brain barrier opening

por Chen, Thomas C., Wang, Weijun, Schönthal, Axel H.
Publicado 2023

Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases

por Chen, Thomas C., Da Fonseca, Clovis O., Schönthal, Axel H.
Publicado 2016

NEO212: sub-cytotoxic doses capable of inhibiting glioma stem cell invasion

por Marín-Ramos, Nagore I., Hofman, Florence M., Chen, Thomas C.
Publicado 2018

Intranasal Perillyl Alcohol for Glioma Therapy: Molecular Mechanisms and Clinical Development

por Chen, Thomas C., da Fonseca, Clovis O., Schönthal, Axel H.
Publicado 2018

DDRE-06. REGULATION OF TUMOR MICROENVIRONMENT VIA ENDOTHELIAL-TO-MESENCHYMAL TRANSITION BLOCKADE IN GLIOBLASTOMA-ASSOCIATED BRAIN ENDOTHELIAL CELLS

por Marin’ Ramos, Nagore I, Jhaveri, Niyati, Thein, Thu Zan, Chen, Thomas C
Publicado 2021

The Monoterpenoid Perillyl Alcohol: Anticancer Agent and Medium to Overcome Biological Barriers

por Chen, Thomas C., da Fonseca, Clovis O., Levin, Daniel, Schönthal, Axel H.
Publicado 2021

Reduced non-CpG methylation is a potential epigenetic target after spinal cord injury

por Wu, Zhourui, Li, Chen, Zhu, Ran, Cao, Yiqiu, Chen, Thomas C., Cheng, Liming
Publicado 2023

Distribution of cancer stem cells in two human brain gliomas

por Peng, Lilei, Fu, Jie, Wang, Weijun, Hofman, Florence M., Chen, Thomas C., Chen, Ligang
Publicado 2019

Intranasal Delivery of miR133b in a NEO100-Based Formulation Induces a Healing Response in Spinal Cord-Injured Mice

por Danilov, Camelia A., Thein, Thu Zan, Tahara, Stanley M., Schönthal, Axel H., Chen, Thomas C.
Publicado 2023

Temozolomide-perillyl alcohol conjugate induced reactive oxygen species accumulation contributes to its cytotoxicity against non-small cell lung cancer

por Song, Xingguo, Xie, Li, Wang, Xingwu, Zeng, Qian, Chen, Thomas C., Wang, Weijun, Song, Xianrang
Publicado 2016

Temozolomide–perillyl alcohol conjugate downregulates O(6)-methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer

por Song, Xingguo, Xie, Li, Chang, Minghui, Geng, Xinran, Wang, Xingwu, Chen, Thomas C., Song, Xianrang
Publicado 2018

Rare Stochastic Expression of O6-Methylguanine- DNA Methyltransferase (MGMT) in MGMT-Negative Melanoma Cells Determines Immediate Emergence of Drug-Resistant Populations upon Treat...

por Chen, Thomas C., Chan, Nymph, Minea, Radu O., Hartman, Hannah, Hofman, Florence M., Schönthal, Axel H.
Publicado 2018

A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice

por Swenson, Steve, Minea, Radu O., Tuan, Cao Duc, Thein, Thu-Zan, Chen, Thomas C., Markland, Francis S.
Publicado 2018

NEO212, a Perillyl Alcohol-Temozolomide Conjugate, Triggers Macrophage Differentiation of Acute Myeloid Leukemia Cells and Blocks Their Tumorigenicity

por Chen, Thomas C., Minea, Radu O., Swenson, Steve, Yang, Zhuoyue, Thein, Thu Zan, Schönthal, Axel H.
Publicado 2022

Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation

por Chang, Minghui, Song, Xingguo, Geng, Xinran, Wang, Xingwu, Wang, Weijun, Chen, Thomas C., Xie, Li, Song, Xianrang
Publicado 2018

Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

por Chen, Thomas C., Chan, Nymph, Labib, Shirin, Yu, Jiali, Cho, Hee-Yeon, Hofman, Florence M., Schönthal, Axel H.
Publicado 2018

NEO212 induces mitochondrial apoptosis and impairs autophagy flux in ovarian cancer

por Song, Xingguo, Liu, Lisheng, Chang, Minghui, Geng, Xinran, Wang, Xingwu, Wang, Weijun, Chen, Thomas C., Xie, Li, Song, Xianrang
Publicado 2019

Fasting Enhances the Response of Glioma to Chemo- and Radiotherapy

por Safdie, Fernando, Brandhorst, Sebastian, Wei, Min, Wang, Weijun, Lee, Changhan, Hwang, Saewon, Conti, Peter S., Chen, Thomas C., Longo, Valter D.
Publicado 2012

Argonaute‐2 Promotes miR‐18a Entry in Human Brain Endothelial Cells

por Ferreira, Raquel, Santos, Tiago, Amar, Arun, Gong, Alex, Chen, Thomas C., Tahara, Stanley M., Giannotta, Steven L., Hofman, Florence M.
Publicado 2014

Heterocellular Contacts with Mouse Brain Endothelial Cells Via Laminin and α6β1 Integrin Sustain Subventricular Zone (SVZ) Stem/Progenitor Cells Properties

por Rosa, Alexandra I., Grade, Sofia, Santos, Sofia D., Bernardino, Liliana, Chen, Thomas C., Relvas, João, Hofman, Florence M., Agasse, Fabienne
Publicado 2016