A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells

por Ray, G. Jordan, Boydston, Elizabeth A., Shortt, Emily, Wyant, Gregory A., Lourido, Sebastian, Chen, Walter W., Sabatini, David M.
Publicado 2020

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

por Birsoy, Kıvanç, Possemato, Richard, Lorbeer, Franziska K., Bayraktar, Erol C., Thiru, Prathapan, Yucel, Burcu, Wang, Tim, Chen, Walter W., Clish, Clary B., Sabatini, David M.
Publicado 2014

MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

por Birsoy, Kivanc, Wang, Tim, Possemato, Richard, Yilmaz, Omer H., Koch, Catherine E., Chen, Walter W., Hutchins, Amanda W., Gultekin, Yetis, Peterson, Tim R., Carette, Jan E., Brummelkamp, Thijn R., Clish, Clary B., Sabatini, David M.
Publicado 2012

MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme

por Li, Yingzhong, Ivica, Nikola A., Dong, Ting, Papageorgiou, Dimitrios P., He, Yanpu, Brown, Douglas R., Kleyman, Marianna, Hu, Guangan, Chen, Walter W., Sullivan, Lucas B., Del Rosario, Amanda, Hammond, Paula T., Vander Heiden, Matthew G., Chen, Jianzhu
Publicado 2020

BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles

por Chen, Walter W, Balaj, Leonora, Liau, Linda M, Samuels, Michael L, Kotsopoulos, Steve K, Maguire, Casey A, LoGuidice, Lori, Soto, Horacio, Garrett, Matthew, Zhu, Lin Dan, Sivaraman, Sarada, Chen, Clark, Wong, Eric T, Carter, Bob S, Hochberg, Fred H, Breakefield, Xandra O, Skog, Johan
Publicado 2013

SHMT2 drives glioma cell survival in the tumor microenvironment but imposes a dependence on glycine clearance

por Kim, Dohoon, Fiske, Brian P., Birsoy, Kivanc, Freinkman, Elizaveta, Kami, Kenjiro, Possemato, Richard, Chudnovsky, Yakov, Pacold, Michael E., Chen, Walter W., Cantor, Jason R., Shelton, Laura M., Gui, Dan Y., Kwon, Manjae, Ramkissoon, Shakti H., Ligon, Keith L., Kang, Seong Woo, Snuderl, Matija, Heiden, Matthew G. Vander, Sabatini, David M.
Publicado 2015

Functional genomics reveals serine synthesis is essential in PHGDH-amplified breast cancer

por Possemato, Richard, Marks, Kevin M., Shaul, Yoav D., Pacold, Michael E., Kim, Dohoon, Birsoy, Kivanç, Sethumadhavan, Shalini, Woo, Hin-Koon, Jang, Hyun G., Jha, Abhishek K., Chen, Walter W., Barrett, Francesca G., Stransky, Nicolas, Tsun, Zhi-Yang, Cowley, Glenn S., Barretina, Jordi, Kalaany, Nada Y., Hsu, Peggy P., Ottina, Kathleen, Chan, Albert M., Yuan, Bingbing, Garraway, Levi A., Root, David E., Mino-Kenudson, Mari, Brachtel, Elena F., Driggers, Edward M., Sabatini, David M.
Publicado 2011

A PHGDH inhibitor reveals coordination of serine synthesis and 1-carbon unit fate

por Pacold, Michael E., Brimacombe, Kyle R., Chan, Sze Ham, Rohde, Jason M., Lewis, Caroline A., Swier, Lotteke J.Y.M., Possemato, Richard, Chen, Walter W., Sullivan, Lucas B., Fiske, Brian P., Cho, Sung Won, Freinkman, Elizaveta, Birsoy, Kıvanç, Abu-Remaileh, Monther, Shaul, Yoav D., Liu, Chieh Min, Zhou, Minerva, Koh, Min Jung, Chung, Haeyoon, Davidson, Shawn M., Luengo, Alba, Wang, Amy Q., Xu, Xin, Yasgar, Adam, Liu, Li, Rai, Ganesha, Westover, Kenneth D., Vander Heiden, Matthew G., Shen, Min, Gray, Nathanael S., Boxer, Matthew B., Sabatini, David M.
Publicado 2016