A Review of Single-Cell RNA-Seq Annotation, Integration, and Cell–Cell Communication

por Cheng, Changde, Chen, Wenan, Jin, Hongjian, Chen, Xiang
Publicado 2023

Recent advances and challenges of rare variant association analysis in the biobank sequencing era

por Chen, Wenan, Coombes, Brandon J., Larson, Nicholas B.
Publicado 2022

Automated ventricular systems segmentation in brain CT images by combining low-level segmentation and high-level template matching

por Chen, Wenan, Smith, Rebecca, Ji, Soo-Yeon, Ward, Kevin R, Najarian, Kayvan
Publicado 2009

UMI-count modeling and differential expression analysis for single-cell RNA sequencing

por Chen, Wenan, Li, Yan, Easton, John, Finkelstein, David, Wu, Gang, Chen, Xiang
Publicado 2018

Polydatin alleviates sepsis‑induced acute lung injury via downregulation of Spi‑B

por Liao, Qingwu, Li, Fang, Xue, Mingming, Chen, Wenan, Tao, Zhengang, Song, Yuejiao, Yuan, Ying
Publicado 2023

A rare variant analysis framework using public genotype summary counts to prioritize disease-predisposition genes

por Chen, Wenan, Wang, Shuoguo, Tithi, Saima Sultana, Ellison, David W., Schaid, Daniel J., Wu, Gang
Publicado 2022

A comparison of methods accounting for batch effects in differential expression analysis of UMI count based single cell RNA sequencing

por Chen, Wenan, Zhang, Silu, Williams, Justin, Ju, Bensheng, Shaner, Bridget, Easton, John, Wu, Gang, Chen, Xiang
Publicado 2020

Evaluation of association tests for rare variants using simulated data sets in the Genetic Analysis Workshop 17 data

por Chen, Wenan, Gao, Xi, Wang, Jiexun, Sun, Chuanyu, Wan, Wen, Zhi, Degui, Liu, Nianjun, Chen, Xiangning, Gao, Guimin
Publicado 2011

Double genomic control is not effective to correct for population stratification in meta-analysis for genome-wide association studies

por Wang, Shudong, Chen, Wenan, Chen, Xiangning, Hu, Fengjiao, Archer, Kellie J., Liu, hb Nianjun, Sun, Shumei, Gao, Guimin
Publicado 2012

Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data

por Cheng, Changde, Easton, John, Rosencrance, Celeste, Li, Yan, Ju, Bensheng, Williams, Justin, Mulder, Heather L, Pang, Yakun, Chen, Wenan, Chen, Xiang
Publicado 2019

Germline landscape of RPA1, RPA2 and RPA3 variants in pediatric malignancies: identification of RPA1 as a novel cancer predisposition candidate gene

por Sharma, Richa, Oak, Ninad, Chen, Wenan, Gogal, Rose, Kirschner, Martin, Beier, Fabian, Schnieders, Michael J., Spies, Maria, Nichols, Kim E., Wlodarski, Marcin
Publicado 2023

MethylPCA: a toolkit to control for confounders in methylome-wide association studies

por Chen, Wenan, Gao, Guimin, Nerella, Srilaxmi, Hultman, Christina M, Magnusson, Patrik KE, Sullivan, Patrick F, Aberg, Karolina A, van den Oord, Edwin JCG
Publicado 2013

Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts

por Ward, Joey, Graham, Nicholas, Strawbridge, Rona J., Ferguson, Amy, Jenkins, Gregory, Chen, Wenan, Hodgson, Karen, Frye, Mark, Weinshilboum, Richard, Uher, Rudolf, Lewis, Cathryn M., Biernacka, Joanna, Smith, Daniel J.
Publicado 2018

Accurate genomic variant detection in single cells with primary template-directed amplification

por Gonzalez-Pena, Veronica, Natarajan, Sivaraman, Xia, Yuntao, Klein, David, Carter, Robert, Pang, Yakun, Shaner, Bridget, Annu, Kavya, Putnam, Daniel, Chen, Wenan, Connelly, Jon, Pruett-Miller, Shondra, Chen, Xiang, Easton, John, Gawad, Charles
Publicado 2021

S107: IDENTIFICATION AND CHARACTERIZATION OF GERMLINE NBN VARIANTS RELATED TO B-ALL PREDISPOSITION

por Escherich, Carolin, Chen, Wenan, Yang, Wenjian, Teachey, David T., Raetz, Elizabeth A., Devidas, Meenakshi, Wu, Gang, Nichols, Kim E., Inaba, Hiroto, Pui, Ching-Hon, Jeha, Sima, Hunger, Stephen P., Loh, Mignon L., Yang, Jun J.
Publicado 2023

Metabolic heterogeneity underlies reciprocal fates of T(H)17 cell stemness and plasticity

por Karmaus, Peer W F, Chen, Xiang, Lim, Seon Ah, Herrada, Andrés A, Nguyen, Thanh-Long M, Xu, Beisi, Dhungana, Yogesh, Rankin, Sherri, Chen, Wenan, Rosencrance, Celeste, Yang, Kai, Fan, Yiping, Cheng, Yong, Easton, John, Neale, Geoffrey, Vogel, Peter, Chi, Hongbo
Publicado 2018

Identification of TCF3 germline variants in pediatric B-cell acute lymphoblastic leukemia

por Escherich, Carolin, Chen, Wenan, Miyamoto, Satoshi, Namikawa, Yui, Yang, Wenjian, Teachey, David T., Li, Zhenhua, Raetz, Elizabeth A., Larsen, Eric, Devidas, Meenakshi, Martin, Paul L., Bowman, W. Paul, Wu, Gang, Pui, Ching-Hon, Hunger, Stephen P., Loh, Mignon L., Takagi, Masatoshi, Yang, Jun J.
Publicado 2022

Germline Genetic NBN Variation and Predisposition to B-cell Acute Lymphoblastic Leukemia in Children

por Escherich, Carolin, Chen, Wenan, Li, Yizhen, Yang, Wenjian, Nishii, Rina, Li, Zhenhua, Raetz, Elizabeth A., Devidas, Meenakshi, Wu, Gang, Nichols, Kim E., Inaba, Hiroto, Pui, Ching-Hon, Jeha, Sima, Camitta, Bruce M., Larsen, Eric, Hunger, Stephen P., Loh, Mignon L., Yang, Jun J.
Publicado 2023

Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma

por Fang, Jie, Singh, Shivendra, Cheng, Changde, Natarajan, Sivaraman, Sheppard, Heather, Abu-Zaid, Ahmed, Durbin, Adam D., Lee, Ha Won, Wu, Qiong, Steele, Jacob, Connelly, Jon P., Jin, Hongjian, Chen, Wenan, Fan, Yiping, Pruett-Miller, Shondra M., Rehg, Jerold E., Koo, Selene C., Santiago, Teresa, Emmons, Joseph, Cairo, Stefano, Wang, Ruoning, Glazer, Evan S., Murphy, Andrew J., Chen, Taosheng, Davidoff, Andrew M., Armengol, Carolina, Easton, John, Chen, Xiang, Yang, Jun
Publicado 2023

Enrichment of heterozygous germline RECQL4 loss-of-function variants in pediatric osteosarcoma

por Maciaszek, Jamie L., Oak, Ninad, Chen, Wenan, Hamilton, Kayla V., McGee, Rose B., Nuccio, Regina, Mostafavi, Roya, Hines-Dowell, Stacy, Harrison, Lynn, Taylor, Leslie, Gerhardt, Elsie L., Ouma, Annastasia, Edmonson, Michael N., Patel, Aman, Nakitandwe, Joy, Pappo, Alberto S., Azzato, Elizabeth M., Shurtleff, Sheila A., Ellison, David W., Downing, James R., Hudson, Melissa M., Robison, Leslie L., Santana, Victor, Newman, Scott, Zhang, Jinghui, Wang, Zhaoming, Wu, Gang, Nichols, Kim E., Kesserwan, Chimene A.
Publicado 2019