Synaptic dysfunction in Down syndrome: an emerging role for circulating β2-microglobulin

por Chen, Xu-Qiao
Publicado 2023

Involvement of T-complex protein 1-ring complex/chaperonin containing T-complex protein 1 (TRiC/CCT) in retrograde axonal transport through tau phosphorylation

por Chen, Xu-Qiao
Publicado 2019

A pilot exploration with Posiphen to normalize amyloid precursor protein in Down syndrome

por Chen, Xu-Qiao
Publicado 2021

Exploring the Pathogenesis of Alzheimer Disease in Basal Forebrain Cholinergic Neurons: Converging Insights From Alternative Hypotheses

por Chen, Xu-Qiao, Mobley, William C.
Publicado 2019

Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species

por Chen, Xu-Qiao, Mobley, William C.
Publicado 2019

The Role of TGF-β and Its Receptors in Gastrointestinal Cancers

por Luo, Jingwen, Chen, Xu-Qiao, Li, Ping
Publicado 2019

Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

por Chen, Xu-Qiao, Das, Utpal, Park, Gooho, Mobley, William C.
Publicado 2021

Clinical opioids differentially induce co-internalization of μ- and δ-opioid receptors

por Bao, Fenghua, Li, Chang-Lin, Chen, Xu-Qiao, Lu, Ying-Jin, Bao, Lan, Zhang, Xu
Publicado 2018

Targeting increased levels of APP in Down syndrome: Posiphen‐mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model

por Chen, Xu‐Qiao, Salehi, Ahmad, Pearn, Matthew L., Overk, Cassia, Nguyen, Phuong D., Kleschevnikov, Alexander M., Maccecchini, Maria, Mobley, William C.
Publicado 2020

Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome

por Chen, Xu-Qiao, Xing, Zhuo, Chen, Quang-Di, Salvi, Richard J., Zhang, Xuming, Tycko, Benjamin, Mobley, William C., Yu, Y. Eugene
Publicado 2021

Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression

por Chen, Xu-Qiao, Barrero, Carlos A., Vasquez-Del Carpio, Rodrigo, Reddy, E. Premkumar, Fecchio, Chiara, Merali, Salim, Deglincerti, Alessia, Fang, Cheng, Rogers, Jack, Maccecchini, Maria L.
Publicado 2021

Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy

por Mo, Zhongying, Zhao, Xiaobei, Liu, Huaqing, Hu, Qinghua, Chen, Xu-Qiao, Pham, Jessica, Wei, Na, Liu, Ze, Zhou, Jiadong, Burgess, Robert W., Pfaff, Samuel L., Caskey, C. Thomas, Wu, Chengbiao, Bai, Ge, Yang, Xiang-Lei
Publicado 2018