Unveiling the interplay between mutational signatures and tumor microenvironment: a pan-cancer analysis

por Luo, Li-Zhi, Li, Sheng, Wei, Chen, Ma, Jiao, Qian, Li-Mei, Chen, Yan-Xing, Wang, Shi-Xiang, Zhao, Qi
Publicado 2023

Alteration in TET1 as potential biomarker for immune checkpoint blockade in multiple cancers

por Wu, Hao-Xiang, Chen, Yan-Xing, Wang, Zi-Xian, Zhao, Qi, He, Ming-Ming, Wang, Ying-Nan, Wang, Feng, Xu, Rui-Hua
Publicado 2019

POLE/POLD1 mutation in non‐exonuclease domain matters for predicting efficacy of immune‐checkpoint‐inhibitor therapy

por Chen, Yan‐Xing, Wang, Zi‐Xian, Yuan, Shu‐Qiang, Jiang, Teng‐Jia, Huang, You‐Sheng, Xu, Rui‐Hua, Wang, Feng, Zhao, Qi
Publicado 2021

Elevated peripheral blood neutrophil-to-lymphocyte ratio is associated with an immunosuppressive tumour microenvironment and decreased benefit of PD-1 antibody in advanced gastric...

por Ruan, Dan-Yun, Chen, Yan-Xing, Wei, Xiao-Li, Wang, Ying-Nan, Wang, Zi-Xian, Wu, Hao-Xiang, Xu, Rui-Hua, Yuan, Shu-Qiang, Wang, Feng-Hua
Publicado 2021

Integrated analysis of single-cell and bulk RNA sequencing data reveals a pan-cancer stemness signature predicting immunotherapy response

por Zhang, Zhen, Wang, Zi-Xian, Chen, Yan-Xing, Wu, Hao-Xiang, Yin, Ling, Zhao, Qi, Luo, Hui-Yan, Zeng, Zhao-Lei, Qiu, Miao-Zhen, Xu, Rui-Hua
Publicado 2022

Clinical Benefit of First-Line Programmed Death-1 Antibody Plus Chemotherapy in Low Programmed Cell Death Ligand 1–Expressing Esophageal Squamous Cell Carcinoma: A Post Hoc Analysi...

por Wu, Hao-Xiang, Pan, Yi-Qian, He, Ye, Wang, Zi-Xian, Guan, Wen-Long, Chen, Yan-Xing, Yao, Yi-Chen, Shao, Ning-Yi, Xu, Rui-Hua, Wang, Feng
Publicado 2023

DNA methylation regulator-mediated modification patterns and tumor microenvironment characterization in gastric cancer

por Meng, Qi, Lu, Yun-Xin, Ruan, Dan-Yun, Yu, Kai, Chen, Yan-Xing, Xiao, Min, Wang, Yun, Liu, Ze-Xian, Xu, Rui-Hua, Ju, Huai-Qiang, Qiu, Miao-Zhen
Publicado 2021

Glucose metabolism inhibitor PFK-015 combined with immune checkpoint inhibitor is an effective treatment regimen in cancer

por Zheng, Jia Bo, Wong, Chau Wei, Liu, Jia, Luo, Xiao-Jing, Zhou, Wei-Yi, Chen, Yan-Xing, Luo, Hui-Yan, Zeng, Zhao-Lei, Ren, Chao, Xie, Xiao-Ming, Wang, De-Shen
Publicado 2022

Methionine deficiency facilitates antitumour immunity by altering m(6)A methylation of immune checkpoint transcripts

por Li, Ting, Tan, Yue-Tao, Chen, Yan-Xing, Zheng, Xiao-Jun, Wang, Wen, Liao, Kun, Mo, Hai-Yu, Lin, Junzhong, Yang, Wei, Piao, Hai-Long, Xu, Rui-Hua, Ju, Huai-Qiang
Publicado 2023

LncRNA TMPO-AS1 promotes esophageal squamous cell carcinoma progression by forming biomolecular condensates with FUS and p300 to regulate TMPO transcription

por Luo, Xiao-Jing, He, Ming-Ming, Liu, Jia, Zheng, Jia-Bo, Wu, Qi-Nian, Chen, Yan-Xing, Meng, Qi, Luo, Kong-Jia, Chen, Dong-Liang, Xu, Rui-Hua, Zeng, Zhao-Lei, Liu, Ze-Xian, Luo, Hui-Yan
Publicado 2022

The liver microenvironment orchestrates FGL1-mediated immune escape and progression of metastatic colorectal cancer

por Li, Jia-Jun, Wang, Jin-Hong, Tian, Tian, Liu, Jia, Zheng, Yong-Qiang, Mo, Hai-Yu, Sheng, Hui, Chen, Yan-Xing, Wu, Qi-Nian, Han, Yi, Liao, Kun, Pan, Yi-Qian, Zeng, Zhao-Lei, Liu, Ze-Xian, Yang, Wei, Xu, Rui-Hua, Ju, Huai-Qiang
Publicado 2023

Genomic temporal heterogeneity of circulating tumour DNA in unresectable metastatic colorectal cancer under first-line treatment

por Wang, Feng, Huang, You-Sheng, Wu, Hao-Xiang, Wang, Zi-Xian, Jin, Ying, Yao, Yi-Chen, Chen, Yan-Xing, Zhao, Qi, Chen, Shifu, He, Ming-Ming, Luo, Hui-Yan, Qiu, Miao-Zhen, Wang, De-shen, Wang, Feng-Hua, Xu, Mingyan, Li, Yu-Hong, Xu, Rui-Hua
Publicado 2022

The lncRNA XIST/miR‐125b‐2‐3p axis modulates cell proliferation and chemotherapeutic sensitivity via targeting Wee1 in colorectal cancer

por Zeng, Zhao‐lei, Lu, Jia‐huan, Wang, Yun, Sheng, Hui, Wang, Ying‐nan, Chen, Zhan‐hong, Wu, Qi‐nian, Zheng, Jia‐Bo, Chen, Yan‐xing, Yang, Dong‐dong, Yu, Kai, Mo, Hai‐yu, Hu, Jia‐jia, Hu, Pei‐shan, Liu, Ze‐xian, Ju, Huai‐qiang, Xu, Rui‐Hua
Publicado 2021

LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer

por Wang, Yun, Lu, Jia-Huan, Wu, Qi-Nian, Jin, Ying, Wang, De-Shen, Chen, Yan-Xing, Liu, Jia, Luo, Xiao-Jing, Meng, Qi, Pu, Heng-Ying, Wang, Ying-Nan, Hu, Pei-Shan, Liu, Ze-Xian, Zeng, Zhao-Lei, Zhao, Qi, Deng, Rong, Zhu, Xiao-Feng, Ju, Huai-Qiang, Xu, Rui-Hua
Publicado 2019

Residual circulating tumor DNA after adjuvant chemotherapy effectively predicts recurrence of stage II‐III gastric cancer

por Yuan, Shu‐Qiang, Nie, Run‐Cong, Huang, You‐Sheng, Chen, Ying‐Bo, Wang, Si‐Yu, Sun, Xiao‐Wei, Li, Yuan‐Fang, Liu, Ze‐Kun, Chen, Yan‐Xing, Yao, Yi‐Chen, Xu, Yu, Qiu, Hai‐Bo, Liang, Yao, Wang, Wei, Liu, Ze‐Xian, Zhao, Qi, Xu, Rui‐Hua, Zhou, Zhi‐Wei, Wang, Feng
Publicado 2023

Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma

por Liu, Jia, Zhou, Wei‐Yi, Luo, Xiao‐Jing, Chen, Yan‐Xing, Wong, Chau‐Wei, Liu, Ze‐Xian, Bo Zheng, Jia‐, Yu Mo, Hai‐, Chen, Jun‐Quan, Li, Jia‐Jun, Zhong, Ming, Xu, Yu‐Hong, Zhang, Qi‐Hua, Pu, Heng‐Ying, Wu, Qi‐Nian, Jin, Ying, Wang, Zi‐Xian, Xu, Rui‐Hua, Luo, Hui‐Yan
Publicado 2023

VDR–SOX2 signaling promotes colorectal cancer stemness and malignancy in an acidic microenvironment

por Hu, Pei-Shan, Li, Ting, Lin, Jin-Fei, Qiu, Miao-Zhen, Wang, De-Shen, Liu, Ze-Xian, Chen, Zhan-Hong, Yang, Lu-Ping, Zhang, Xiao-Long, Zhao, Qi, Chen, Yan-Xing, Lu, Yun-Xin, Wu, Qi-Nian, Pu, Heng-Ying, Zeng, Zhao-Lei, Xie, Dan, Ju, Huai-Qiang, Luo, Hui-Yan, Xu, Rui-Hua
Publicado 2020

Systematic analysis of the transcriptome in small‐cell carcinoma of the oesophagus reveals its immune microenvironment

por Zhao, Qi, Chen, Yan‐Xing, Wu, Qi‐Nian, Zhang, Chao, Liu, Min, Wang, Ying‐Nan, Feng, Yan‐Fen, Hu, Jia‐Jia, Fu, Jian‐Hua, Yang, Hong, Qi, Jing‐Jing, Wang, Zi‐Xian, Lu, Yun‐Xin, Sheng, Hui, Liu, Ze‐Xian, Zuo, Zhi‐Xiang, Zheng, Jian, Yun, Jing‐Ping, Bei, Jin‐Xin, Jia, Wei‐Hua, Lin, Dong‐Xin, Xu, Rui‐hua, Wang, Feng
Publicado 2020

Comprehensive profiling of 1015 patients’ exomes reveals genomic-clinical associations in colorectal cancer

por Zhao, Qi, Wang, Feng, Chen, Yan-Xing, Chen, Shifu, Yao, Yi-Chen, Zeng, Zhao-Lei, Jiang, Teng-Jia, Wang, Ying-Nan, Wu, Chen-Yi, Jing, Ying, Huang, You-Sheng, Zhang, Jing, Wang, Zi-Xian, He, Ming-Ming, Pu, Heng-Ying, Mai, Zong-Jiong, Wu, Qi-Nian, Long, Renwen, Zhang, Xiaoni, Huang, Tanxiao, Xu, Mingyan, Qiu, Miao-Zheng, Luo, Hui-Yan, Li, Yu-Hong, Zhang, Dong-Shen, Jia, Wei-Hua, Chen, Gong, Ding, Pei-Rong, Li, Li-Ren, Lu, Zheng-Hai, Pan, Zhi-Zhong, Xu, Rui-Hua
Publicado 2022