A novel graph convolutional neural network for predicting interaction sites on protein kinase inhibitors in phosphorylation

por Wang, Feiqi, Chen, Yun-Ti, Yang, Jinn-Moon, Akutsu, Tatsuya
Publicado 2022

Inhibition of IRAK1 Is an Effective Therapy for Autoimmune Hypophysitis in Mice

por Huang, Hsiao-Chen, Chen, Yun-Ti, Lin, Han-Huei, Li, Zhi-Qin, Yang, Jinn-Moon, Tzou, Shey-Cherng
Publicado 2022

Repurposing existing drugs: identification of SARS-CoV-2 3C-like protease inhibitors

por Chiou, Wei-Chung, Hsu, Meng-Shiuan, Chen, Yun-Ti, Yang, Jinn-Moon, Tsay, Yeou-Guang, Huang, Hsiu-Chen, Huang, Cheng
Publicado 2021

Exploring kinase family inhibitors and their moiety preferences using deep SHapley additive exPlanations

por Fan, You-Wei, Liu, Wan-Hsin, Chen, Yun-Ti, Hsu, Yen-Chao, Pathak, Nikhil, Huang, Yu-Wei, Yang, Jinn-Moon
Publicado 2022

Identification of pan-kinase-family inhibitors using graph convolutional networks to reveal family-sensitive pre-moieties

por Lin, Xiang-Yu, Huang, Yu-Wei, Fan, You-Wei, Chen, Yun-Ti, Pathak, Nikhil, Hsu, Yen-Chao, Yang, Jinn-Moon
Publicado 2022

The inhibitory effects of PGG and EGCG against the SARS-CoV-2 3C-like protease

por Chiou, Wei-Chung, Chen, Jui-Chieh, Chen, Yun-Ti, Yang, Jinn-Moon, Hwang, Lih-Hwa, Lyu, Yi-Shuan, Yang, Hsin-Yi, Huang, Cheng
Publicado 2022

Discovery of moiety preference by Shapley value in protein kinase family using random forest models

por Huang, Yu-Wei, Hsu, Yen-Chao, Chuang, Yi-Hsuan, Chen, Yun-Ti, Lin, Xiang-Yu, Fan, You-Wei, Pathak, Nikhil, Yang, Jinn-Moon
Publicado 2022

Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5‐diamino‐6‐chloro‐N‐(N‐(2,6‐dichlorobenzoyl)carbamimidoyl)pyrazine‐2‐carboxide...

por Lee, Chien‐Chin, Chang, Wen‐Hsin, Chang, Ya‐Sian, Yang, Jinn‐Moon, Chang, Chih‐Shiang, Hsu, Kai‐Cheng, Chen, Yun‐Ti, Liu, Ting‐Yuan, Chen, Yu‐Chia, Lin, Shyr‐Yi, Wu, Yang‐Chang, Chang, Jan‐Gowth
Publicado 2019

Methotrexate inhibition of SARS-CoV-2 entry, infection and inflammation revealed by bioinformatics approach and a hamster model

por Chen, Yun-Ti, Chang, Yu-Hsiu, Pathak, Nikhil, Tzou, Shey-Cherng, Luo, Yong-Chun, Hsu, Yen-Chao, Li, Tian-Neng, Lee, Jung-Yu, Chen, Yi-Cyun, Huang, Yu-Wei, Yang, Hsin-Ju, Hsu, Nung-Yu, Tsai, Hui-Ping, Chang, Tein-Yao, Hsu, Shu-Chen, Liu, Ping-Cheng, Chin, Yuan-Fan, Lin, Wen-Chin, Yang, Chuen-Mi, Wu, Hsueh-Ling, Lee, Chia-Ying, Hsu, Hui-Ling, Liu, Yi-Chun, Chu, Jhih-Wei, Wang, Lily Hui-Ching, Wang, Jann-Yuan, Huang, Chih-Heng, Lin, Chi-Hung, Hsieh, Po-Shiuan, Wu Lee, Yan-Hwa, Hung, Yi-Jen, Yang, Jinn-Moon
Publicado 2022