How the Signaling Crosstalk of B Cell Receptor (BCR) and Co-Receptors Regulates Antibody Class Switch Recombination: A New Perspective of Checkpoints of BCR Signaling

por Chen, Zhangguo, Wang, Jing H.
Publicado 2021

Why responses to immune checkpoint inhibitors are heterogeneous in head and neck cancers: Contributions from tumor-intrinsic and host-intrinsic factors

por Chen, Zhangguo, John, Jessy, Wang, Jing H.
Publicado 2022

Chemotherapy-induced differential cell cycle arrest in B-cell lymphomas affects their sensitivity to Wee1 inhibition

por Wang, Xiaoguang, Chen, Zhangguo, Mishra, Ameet K., Silva, Alexa, Ren, Wenhua, Pan, Zenggang, Wang, Jing H.
Publicado 2018

TRAF2/3 deficient B cells resist DNA damage-induced apoptosis via NF-κB2/XIAP/cIAP2 axis and IAP antagonist sensitizes mutant lymphomas to chemotherapeutic drugs

por Vashisht, Monika, Ge, Huaibin, John, Jessy, McKelvey, Harlie A., Chen, Jingxin, Chen, Zhangguo, Wang, Jing H.
Publicado 2023

Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8(+) T Cells co-expressing PD-1 and LAG-3 inhibitory receptors

por Mishra, Ameet K., Kadoishi, Tanya, Wang, Xiaoguang, Driver, Emily, Chen, Zhangguo, Wang, Xiao-Jing, Wang, Jing H.
Publicado 2016

HDAC inhibitors overcome immunotherapy resistance in B-cell lymphoma

por Wang, Xiaoguang, Waschke, Brittany C., Woolaver, Rachel A, Chen, Samantha M. Y., Chen, Zhangguo, Wang, Jing H.
Publicado 2020

Host-specific differences in top-expanded TCR clonotypes correlate with divergent outcomes of anti-PD-L1 treatment in responders versus non-responders

por John, Jessy, Chen, Samantha M. Y., Woolaver, Rachel A., Ge, Huaibin, Vashisht, Monika, Huang, Ziyu, Chen, Zhangguo, Wang, Jing H.
Publicado 2023

Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity

por Chen, Zhangguo, Elos, Mihret T., Viboolsittiseri, Sawanee S., Gowan, Katherine, Leach, Sonia M., Rice, Michael, Eder, Maxwell D., Jones, Kenneth, Wang, Jing H.
Publicado 2016

Unexpected effects of different genetic backgrounds on identification of genomic rearrangements via whole-genome next generation sequencing

por Chen, Zhangguo, Gowan, Katherine, Leach, Sonia M., Viboolsittiseri, Sawanee S., Mishra, Ameet K., Kadoishi, Tanya, Diener, Katrina, Gao, Bifeng, Jones, Kenneth, Wang, Jing H.
Publicado 2016

CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells

por Chen, Zhangguo, Chen, Lanfen, Baker, Kristi, Olszak, Torsten, Zeissig, Sebastian, Huang, Yu-Hwa, Kuo, Timothy T., Mandelboim, Ofer, Beauchemin, Nicole, Lanier, Lewis L., Blumberg, Richard S.
Publicado 2011

Divergent outcomes of anti-PD-L1 treatment coupled with host-intrinsic differences in TCR repertoire and distinct T cell activation states in responding versus non-responding tumor...

por John, Jessy, Woolaver, Rachel A., Popolizio, Vince, Chen, Samantha M. Y., Ge, Huaibin, Krinsky, Alexandra L., Vashisht, Monika, Kramer, Yonatan, Chen, Zhangguo, Wang, Jing H.
Publicado 2022

Cytosolic PLA(2) is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15

por Tang, Fangming, Chen, Zhangguo, Ciszewski, Cezary, Setty, Mala, Solus, Jason, Tretiakova, Maria, Ebert, Ellen, Han, Jin, Lin, Anning, Guandalini, Stefano, Groh, Veronika, Spies, Thomas, Green, Peter, Jabri, Bana
Publicado 2009

Hydrogen bonds are a primary driving force for de novo protein folding

por Lee, Schuyler, Wang, Chao, Liu, Haolin, Xiong, Jian, Jiji, Renee, Hong, Xia, Yan, Xiaoxue, Chen, Zhangguo, Hammel, Michal, Wang, Yang, Dai, Shaodong, Wang, Jing, Jiang, Chengyu, Zhang, Gongyi
Publicado 2017

Hydrogen bonds are a primary driving force for de novo protein folding. Corrigendum

por Lee, Schuyler, Wang, Chao, Liu, Haolin, Xiong, Jian, Jiji, Renee, Hong, Xia, Yan, Xiaoxue, Chen, Zhangguo, Hammel, Michal, Wang, Yang, Dai, Shaodong, Wang, Jing, Jiang, Chengyu, Zhang, Gongyi
Publicado 2018

Deletion of p53 and Hyper-Activation of PIK3CA in Keratin-15(+) Stem Cells Lead to the Development of Spontaneous Squamous Cell Carcinoma

por Chen, Samantha M. Y., Bian, Li, Nicklawsky, Andrew G., Krinsky, Alexandra L., Brunetti, Tonya, Woolaver, Rachel A., Wang, Xiaoguang, Chen, Zhangguo, Young, Christian D., Gao, Dexiang, Wang, Xiao-Jing, Wang, Jing H.
Publicado 2020

Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts

por Woolaver, Rachel A, Wang, Xiaoguang, Krinsky, Alexandra L, Waschke, Brittany C, Chen, Samantha M Y, Popolizio, Vince, Nicklawsky, Andrew G, Gao, Dexiang, Chen, Zhangguo, Jimeno, Antonio, Wang, Xiao-Jing, Wang, Jing Hong
Publicado 2021

Differential responses to immune checkpoint inhibitor dictated by pre-existing differential immune profiles in squamous cell carcinomas caused by same initial oncogenic drivers

por Chen, Samantha M. Y., Popolizio, Vince, Woolaver, Rachel A., Ge, Huaibin, Krinsky, Alexandra L., John, Jessy, Danis, Etienne, Ke, Yao, Kramer, Yonatan, Bian, Li, Nicklawsky, Andrew G., Gao, Dexiang, Liu, Silvia, Chen, Zhangguo, Wang, Xiao-jing, Wang, Jing H.
Publicado 2022