Curcumin ameliorates H(2)O(2)-induced inflammatory response in chondrocytes by inducing autophagy activation

por Qi, Hai-Liang, Chen, Zheng-Yi, Qin, Yu-Huan, Li, Ya-Zhai
Publicado 2022

Disrupting the Interaction between Retinoblastoma Protein and Raf-1 Leads to Defects in Progenitor Cell Proliferation and Survival during Early Inner Ear Development

por Li, Wenyan, Sun, Shan, Chen, Yan, Yu, Huiqian, Chen, Zheng-Yi, Li, Huawei
Publicado 2013

Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo

por Shu, Yilai, Tao, Yong, Li, Wenyan, Shen, Jun, Wang, Zhengmin, Chen, Zheng-Yi
Publicado 2016

A Novel in vitro Model Delineating Hair Cell Regeneration and Neural Reinnervation in Adult Mouse Cochlea

por Li, Wenyan, Quan, Yizhou, Huang, Mingqian, Wei, Wei, Shu, Yilai, Li, Huawei, Chen, Zheng-Yi
Publicado 2022

Stem Cells and Gene Therapy in Progressive Hearing Loss: the State of the Art

por Nourbakhsh, Aida, Colbert, Brett M., Nisenbaum, Eric, El-Amraoui, Aziz, Dykxhoorn, Derek M., Koehler, Karl Russell, Chen, Zheng-yi, Liu, Xue Z.
Publicado 2021

Generation and Genetic Correction of USH2A c.2299delG Mutation in Patient-Derived Induced Pluripotent Stem Cells

por Liu, Xuezhong, Lillywhite, Justin, Zhu, Wenliang, Huang, Zaohua, Clark, Anna M, Gosstola, Nicholas, Maguire, Colin T., Dykxhoorn, Derek, Chen, Zheng-Yi, Yang, Jun
Publicado 2021

Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice

por Quan, Yi-Zhou, Wei, Wei, Ergin, Volkan, Rameshbabu, Arun Prabhu, Huang, Mingqian, Tian, Chunjie, Saladi, Srinivas Vinod, Indzhykulian, Artur A., Chen, Zheng-Yi
Publicado 2023

The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns

por Liu, Shaofeng, Wang, Yunfeng, Lu, Yongtian, Li, Wen, Liu, Wenjing, Ma, Jun, Sun, Fuqin, Li, Mao, Chen, Zheng-Yi, Su, Kaiming, Li, Wenyan
Publicado 2018

Direct Functional Protein Delivery with a Peptide into Neonatal and Adult Mammalian Inner Ear In Vivo

por Zhang, Kun, Cheng, Xiaoting, Zhao, Liping, Huang, Mingqian, Tao, Yong, Zhang, Hongbo, Rosenholm, Jessica M., Zhuang, Min, Chen, Zheng-Yi, Chen, Bing, Shu, Yilai
Publicado 2020

Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss

por Cui, Chong, Wang, Daqi, Huang, Bowei, Wang, Fang, Chen, Yuxin, Lv, Jun, Zhang, Luping, Han, Lei, Liu, Dong, Chen, Zheng-Yi, Li, Geng-Lin, Li, Huawei, Shu, Yilai
Publicado 2022

Efficient Delivery of Genome-Editing Proteins In Vitro and In Vivo

por Zuris, John A., Thompson, David B., Shu, Yilai, Guilinger, John P., Bessen, Jeffrey L., Hu, Johnny H., Maeder, Morgan L., Joung, J. Keith, Chen, Zheng-Yi, Liu, David R.
Publicado 2014

Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration

por Lee, Sang Goo, Huang, Mingqian, Obholzer, Nikolaus D., Sun, Shan, Li, Wenyan, Petrillo, Marco, Dai, Pu, Zhou, Yi, Cotanche, Douglas A., Megason, Sean G., Li, Huawei, Chen, Zheng-Yi
Publicado 2016

Renewed proliferation in adult mouse cochlea and regeneration of hair cells

por Shu, Yilai, Li, Wenyan, Huang, Mingqian, Quan, Yi-Zhou, Scheffer, Deborah, Tian, Chunjie, Tao, Yong, Liu, Xuezhong, Hochedlinger, Konrad, Indzhykulian, Artur A., Wang, Zhengmin, Li, Huawei, Chen, Zheng-Yi
Publicado 2019

Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates

por Zhang, Longlong, Wang, Hui, Xun, Mengzhao, Tang, Honghai, Wang, Jinghan, Lv, Jun, Zhu, Biyun, Chen, Yuxin, Wang, Daqi, Hu, Shaowei, Gao, Ziwen, Liu, Jianping, Chen, Zheng-Yi, Chen, Bing, Li, Huawei, Shu, Yilai
Publicado 2023

Prevalence of metabolic syndrome among urban community residents in China

por Wang, Guang-Rong, Li, Li, Pan, Yi-Hui, Tian, Guo-Dong, Lin, Wan-Long, Li, Zhe, Chen, Zheng-Yi, Gong, You-Long, Kikano, George E, Stange, Kurt C, Ni, Ke-Liang, Berger, Nathan A
Publicado 2013

Preventing autosomal-dominant hearing loss in Bth mice with CRISPR/CasRx-based RNA editing

por Zheng, Ziwen, Li, Guo, Cui, Chong, Wang, Fang, Wang, Xiaohan, Xu, Zhijiao, Guo, Huiping, Chen, Yuxin, Tang, Honghai, Wang, Daqi, Huang, Mingqian, Chen, Zheng-Yi, Huang, Xingxu, Li, Huawei, Li, Geng-Lin, Hu, Xiaoxiang, Shu, Yilai
Publicado 2022

Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo

por Tao, Yong, Lamas, Veronica, Du, Wan, Zhu, Wenliang, Li, Yiran, Whittaker, Madelynn N., Zuris, John A., Thompson, David B., Rameshbabu, Arun Prabhu, Shu, Yilai, Gao, Xue, Hu, Johnny H., Pei, Charles, Kong, Wei-Jia, Liu, Xuezhong, Wu, Hao, Kleinstiver, Benjamin P., Liu, David R., Chen, Zheng-Yi
Publicado 2023

Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents

por Gao, Xue, Tao, Yong, Lamas, Veronica, Huang, Mingqian, Yeh, Wei-Hsi, Pan, Bifeng, Hu, Yu-Juan, Hu, Johnny H., Thompson, David B., Shu, Yilai, Li, Yamin, Wang, Hongyang, Yang, Shiming, Xu, Qiaobing, Polley, Daniel B., Liberman, M. Charles, Kong, Wei-Jia, Holt, Jeffrey R., Chen, Zheng-Yi, Liu, David R.
Publicado 2017

A nonsense TMEM43 variant leads to disruption of connexin-linked function and autosomal dominant auditory neuropathy spectrum disorder

por Jang, Minwoo Wendy, Oh, Doo-Yi, Yi, Eunyoung, Liu, Xuezhong, Ling, Jie, Kim, Nayoung, Sharma, Kushal, Kim, Tai Young, Lee, Seungmin, Kim, Ah-Reum, Kim, Min Young, Kim, Min-A, Lee, Mingyu, Han, Jin-Hee, Han, Jae Joon, Park, Hye-Rim, Kim, Bong Jik, Lee, Sang-Yeon, Woo, Dong Ho, Oh, Jayoung, Oh, Soo-Jin, Du, Tingting, Koo, Ja-Won, Oh, Seung-Ha, Shin, Hyun-Woo, Seong, Moon-Woo, Lee, Kyu-Yup, Kim, Un-Kyung, Shin, Jung Bum, Sang, Shushan, Cai, Xinzhang, Mei, Lingyun, He, Chufeng, Blanton, Susan H., Chen, Zheng-Yi, Chen, Hongsheng, Liu, Xianlin, Nourbakhsh, Aida, Huang, Zaohua, Kang, Kwon-Woo, Park, Woong-Yang, Feng, Yong, Lee, C. Justin, Choi, Byung Yoon
Publicado 2021

The NIH Somatic Cell Genome Editing program

por Saha, Krishanu, Sontheimer, Erik J., Brooks, P. J., Dwinell, Melinda R., Gersbach, Charles A., Liu, David R., Murray, Stephen A., Tsai, Shengdar Q., Wilson, Ross C., Anderson, Daniel G., Asokan, Aravind, Banfield, Jillian F., Bankiewicz, Krystof S., Bao, Gang, Bulte, Jeff W. M., Bursac, Nenad, Campbell, Jarryd M., Carlson, Daniel F., Chaikof, Elliot L., Chen, Zheng-Yi, Cheng, R. Holland, Clark, Karl J., Curiel, David T., Dahlman, James E., Deverman, Benjamin E., Dickinson, Mary E., Doudna, Jennifer A., Ekker, Stephen C., Emborg, Marina E., Feng, Guoping, Freedman, Benjamin S., Gamm, David M., Gao, Guangping, Ghiran, Ionita C., Glazer, Peter M., Gong, Shaoqin, Heaney, Jason D., Hennebold, Jon D., Hinson, John T., Khvorova, Anastasia, Kiani, Samira, Lagor, William R., Lam, Kit S., Leong, Kam W., Levine, Jon E., Lewis, Jennifer A., Lutz, Cathleen M., Ly, Danith H., Maragh, Samantha, McCray, Paul B., McDevitt, Todd C., Mirochnitchenko, Oleg, Morizane, Ryuji, Murthy, Niren, Prather, Randall S., Ronald, John A., Roy, Subhojit, Roy, Sushmita, Sabbisetti, Venkata, Saltzman, W. Mark, Santangelo, Philip J., Segal, David J., Shimoyama, Mary, Skala, Melissa C., Tarantal, Alice F., Tilton, John C., Truskey, George A., Vandsburger, Moriel, Watts, Jonathan K., Wells, Kevin D., Wolfe, Scot A., Xu, Qiaobing, Xue, Wen, Yi, Guohua, Zhou, Jiangbing
Publicado 2021