APOBEC3 degradation is the primary function of HIV-1 Vif for virus replication in the myeloid cell line THP-1

por Ikeda, Terumasa, Shimizu, Ryo, Nasser, Hesham, Carpenter, Michael A., Cheng, Adam Z., Brown, William L., Sauter, Daniel, Harris, Reuben S.
Publicado 2023

APOBEC3 degradation is the primary function of HIV-1 Vif determining virion infectivity in the myeloid cell line THP-1

por Ikeda, Terumasa, Shimizu, Ryo, Nasser, Hesham, Carpenter, Michael A., Cheng, Adam Z., Brown, William L., Sauter, Daniel, Harris, Reuben S.
Publicado 2023

Evidence linking APOBEC3B genesis and evolution of innate immune antagonism by gamma-herpesvirus ribonucleotide reductases

por Moraes, Sofia N, Becker, Jordan T, Moghadasi, Seyed Arad, Shaban, Nadine M, Auerbach, Ashley A, Cheng, Adam Z, Harris, Reuben S
Publicado 2022

Differential Evolution of Antiretroviral Restriction Factors in Pteropid Bats as Revealed by APOBEC3 Gene Complexity

por Hayward, Joshua A, Tachedjian, Mary, Cui, Jie, Cheng, Adam Z, Johnson, Adam, Baker, Michelle L, Harris, Reuben S, Wang, Lin-Fa, Tachedjian, Gilda
Publicado 2018

Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition

por Shaban, Nadine M., Yan, Rui, Shi, Ke, Moraes, Sofia N., Cheng, Adam Z., Carpenter, Michael A., McLellan, Jason S., Yu, Zhiheng, Harris, Reuben S.
Publicado 2022

APOBECs and Herpesviruses

por Cheng, Adam Z., Moraes, Sofia N., Shaban, Nadine M., Fanunza, Elisa, Bierle, Craig J., Southern, Peter J., Bresnahan, Wade A., Rice, Stephen A., Harris, Reuben S.
Publicado 2021

Human cytomegalovirus mediates APOBEC3B relocalization early during infection through a ribonucleotide reductase-independent mechanism

por Fanunza, Elisa, Cheng, Adam Z., Auerbach, Ashley A., Stefanovska, Bojana, Moraes, Sofia N., Lokensgard, James R., Biolatti, Matteo, Dell'Oste, Valentina, Bierle, Craig J., Bresnahan, Wade A., Harris, Reuben S.
Publicado 2023

Human cytomegalovirus mediates APOBEC3B relocalization early during infection through a ribonucleotide reductase-independent mechanism

por Fanunza, Elisa, Cheng, Adam Z., Auerbach, Ashley A., Stefanovska, Bojana, Moraes, Sofia N., Lokensgard, James R., Biolatti, Matteo, Dell’Oste, Valentina, Bierle, Craig J., Bresnahan, Wade A., Harris, Reuben S.
Publicado 2023

Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity

por Cheng, Adam Z., Yockteng-Melgar, Jaime, Jarvis, Matthew C., Malik-Soni, Natasha, Borozan, Ivan, Carpenter, Michael A., McCann, Jennifer L., Ebrahimi, Diako, Shaban, Nadine M., Marcon, Edyta, Greenblatt, Jack, Brown, William L., Frappier, Lori, Harris, Reuben S.
Publicado 2018

Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease

por Ebrahimi, Diako, Richards, Christopher M., Carpenter, Michael A., Wang, Jiayi, Ikeda, Terumasa, Becker, Jordan T., Cheng, Adam Z., McCann, Jennifer L., Shaban, Nadine M., Salamango, Daniel J., Starrett, Gabriel J., Lingappa, Jairam R., Yong, Jeongsik, Brown, William L., Harris, Reuben S.
Publicado 2018