CRISPR–Cas9-mediated genome editing and guide RNA design

por Wiles, Michael V., Qin, Wenning, Cheng, Albert W., Wang, Haoyi
Publicado 2015

CRISPR-mediated multiplexed live cell imaging of nonrepetitive genomic loci with one guide RNA per locus

por Clow, Patricia A., Du, Menghan, Jillette, Nathaniel, Taghbalout, Aziz, Zhu, Jacqueline J., Cheng, Albert W.
Publicado 2022

Casilio: a versatile CRISPR-Cas9-Pumilio hybrid for gene regulation and genomic labeling

por Cheng, Albert W, Jillette, Nathaniel, Lee, Phoebe, Plaskon, Dylan, Fujiwara, Yasuhiro, Wang, Wenbo, Taghbalout, Aziz, Wang, Haoyi
Publicado 2016

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways

por Taghbalout, Aziz, Du, Menghan, Jillette, Nathaniel, Rosikiewicz, Wojciech, Rath, Abhijit, Heinen, Christopher D., Li, Sheng, Cheng, Albert W.
Publicado 2019

Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells

por Maetzel, Dorothea, Sarkar, Sovan, Wang, Haoyi, Abi-Mosleh, Lina, Xu, Ping, Cheng, Albert W., Gao, Qing, Mitalipova, Maisam, Jaenisch, Rudolf
Publicado 2014

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

por Shapiro, Irina M., Cheng, Albert W., Flytzanis, Nicholas C., Balsamo, Michele, Condeelis, John S., Oktay, Maja H., Burge, Christopher B., Gertler, Frank B.
Publicado 2011

SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

por Lodato, Michael A., Ng, Christopher W., Wamstad, Joseph A., Cheng, Albert W., Thai, Kevin K., Fraenkel, Ernest, Jaenisch, Rudolf, Boyer, Laurie A.
Publicado 2013

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

por Cheng, Albert W, Wang, Haoyi, Yang, Hui, Shi, Linyu, Katz, Yarden, Theunissen, Thorold W, Rangarajan, Sudharshan, Shivalila, Chikdu S, Dadon, Daniel B, Jaenisch, Rudolf
Publicado 2013

Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease

por Qin, Wenning, Dion, Stephanie L., Kutny, Peter M., Zhang, Yingfan, Cheng, Albert W., Jillette, Nathaniel L., Malhotra, Ankit, Geurts, Aron M., Chen, Yi-Guang, Wang, Haoyi
Publicado 2015

Transgenic Mice with Defined Combinations of Drug Inducible Reprogramming Factors

por Markoulaki, Styliani, Hanna, Jacob, Beard, Caroline, Carey, Bryce W., Cheng, Albert W., Lengner, Christopher J., Dausman, Jessica A., Fu, Dongdong, Gao, Qing, Wu, Su, Cassady, John P., Jaenisch, Rudolf
Publicado 2009

TALEN-mediated editing of the Mouse Y Chromosome

por Wang, Haoyi, Hu, Yueh-Chiang, Markoulaki, Styliani, Welstead, G. Grant, Cheng, Albert W., Shivalila, Chikdu S., Pyntikova, Tatyana, Dadon, Daniel B., Voytas, Daniel F., Bogdanove, Adam J., Page, David C., Jaenisch, Rudolf
Publicado 2013

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

por Katz, Yarden, Li, Feifei, Lambert, Nicole J, Sokol, Ethan S, Tam, Wai-Leong, Cheng, Albert W, Airoldi, Edoardo M, Lengner, Christopher J, Gupta, Piyush B, Yu, Zhengquan, Jaenisch, Rudolf, Burge, Christopher B
Publicado 2014

Complex haploinsufficiency in pluripotent cells yields somatic cells with DNA methylation abnormalities and pluripotency induction defects

por Lasry, Rachel, Maoz, Noam, Cheng, Albert W., Yom Tov, Nataly, Kulenkampff, Elisabeth, Azagury, Meir, Yang, Hui, Ople, Cora, Markoulaki, Styliani, Faddah, Dina A., Makedonski, Kirill, Orzech, Dana, Sabag, Ofra, Jaenisch, Rudolf, Buganim, Yosef
Publicado 2023