Growth arrest-specific gene 2 suppresses hepatocarcinogenesis by intervention of cell cycle and p53-dependent apoptosis

por Zhu, Ran-Xu, Cheng, Alfred Sze Lok, Chan, Henry Lik Yuen, Yang, Dong-Ye, Seto, Wai-Kay
Publicado 2019

A proof-of-concept study for the pathogenetic role of enhancer hypomethylation of MYBPHL in multiple myeloma

por Wong, Kwan Yeung, Morgan, Gareth J., Boyle, Eileen M., Cheng, Alfred Sze Lok, Yip, Kevin Yuk-Lap, Chim, Chor Sang
Publicado 2021

C-terminal truncated hepatitis B virus X protein promotes hepatocellular carcinogenesis through induction of cancer and stem cell-like properties

por Ng, Kai-Yu, Chai, Stella, Tong, Man, Guan, Xin-Yuan, Lin, Chi-Ho, Ching, Yick-Pang, Xie, Dan, Cheng, Alfred Sze-Lok, Ma, Stephanie
Publicado 2016

Chemotherapy-induced recruitment of myeloid-derived suppressor cells abrogates efficacy of immune checkpoint blockade

por Kwong, Tsz Tung, Wong, Chi Hang, Zhou, Jing Ying, Cheng, Alfred Sze Lok, Sung, Joseph Jao Yiu, Chan, Anthony Wing Hung, Chan, Stephen Lam
Publicado 2020

START: a system for flexible analysis of hundreds of genomic signal tracks in few lines of SQL-like queries

por Zhu, Xinjie, Zhang, Qiang, Ho, Eric Dun, Yu, Ken Hung-On, Liu, Chris, Huang, Tim H., Cheng, Alfred Sze-Lok, Kao, Ben, Lo, Eric, Yip, Kevin Y.
Publicado 2017

Metabolic enzyme PDK3 forms a positive feedback loop with transcription factor HSF1 to drive chemoresistance

por Xu, Jinye, Shi, Qiqi, Xu, Wenxia, Zhou, Qiyin, Shi, Rongkai, Ma, Yanning, Chen, Dingwei, Zhu, Liyuan, Feng, Lifeng, Cheng, Alfred Sze-Lok, Morrison, Helen, Wang, Xian, Jin, Hongchuan
Publicado 2019

Autism‐associated PTEN missense mutation leads to enhanced nuclear localization and neurite outgrowth in an induced pluripotent stem cell line

por Wong, Chi Wai, Wang, Yubing, Liu, Tian, Li, Lisha, Cheung, Stanley Kwok Kuen, Or, Penelope Mei‐Yu, Cheng, Alfred Sze‐Lok, Choy, Kwong Wai, Burbach, Johannes Peter Henri, Feng, Bo, Chang, Raymond Chuen Chung, Chan, Andrew M.
Publicado 2020

Carboxyl-Terminal Truncated HBx Regulates a Distinct MicroRNA Transcription Program in Hepatocellular Carcinoma Development

por Yip, Wing-Kit, Cheng, Alfred Sze-Lok, Zhu, Ranxu, Lung, Raymond Wai-Ming, Tsang, Daisy Pui-Fong, Lau, Suki Shuk-Kei, Chen, Yangchao, Sung, Jonathan Gabriel, Lai, Paul Bo-San, Ng, Enders Kai-On, Yu, Jun, Wong, Nathalie, To, Ka-Fai, Wong, Vincent Wai-Sun, Sung, Joseph Jao-Yiu, Chan, Henry Lik-Yuen
Publicado 2011

Smad3 Promotes Cancer‐Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition

por Tang, Philip Chiu‐Tsun, Chung, Jeff Yat‐Fai, Xue, Vivian Wei‐wen, Xiao, Jun, Meng, Xiao‐Ming, Huang, Xiao‐Ru, Zhou, Shuang, Chan, Alex Siu‐Wing, Tsang, Anna Chi‐Man, Cheng, Alfred Sze‐Lok, Lee, Tin‐Lap, Leung, Kam‐Tong, Lam, Eric W.‐F., To, Ka‐Fai, Tang, Patrick Ming‐Kuen, Lan, Hui‐Yao
Publicado 2021

Vitamin D(3) and carbamazepine protect against Clostridioides difficile infection in mice by restoring macrophage lysosome acidification

por Chan, Hung, Li, Qing, Wang, Xiansong, Liu, Wing Yingzhi, Hu, Wei, Zeng, Judeng, Xie, Chuan, Kwong, Thomas Ngai Yeung, Ho, Idy Hiu Ting, Liu, Xiaodong, Chen, Huarong, Yu, Jun, Ko, Ho, Chan, Raphael Chiu Yeung, Ip, Margaret, Gin, Tony, Cheng, Alfred Sze Lok, Zhang, Lin, Chan, Matthew Tak Vai, Wong, Sunny Hei, Wu, William Ka Kei
Publicado 2022

Targeting PPAR-gamma counteracts tumour adaptation to immune-checkpoint blockade in hepatocellular carcinoma

por Xiong, Zhewen, Chan, Stephen Lam, Zhou, Jingying, Vong, Joaquim S.L., Kwong, Tsz Tung, Zeng, Xuezhen, Wu, Haoran, Cao, Jianquan, Tu, Yalin, Feng, Yu, Yang, Weiqin, Wong, Patrick Pak-Chun, Si-Tou, Willis Wai-Yiu, Liu, Xiaoyu, Wang, Jing, Tang, Wenshu, Liang, Zhixian, Lu, Jiahuan, Li, Ka Man, Low, Jie-Ting, Chan, Michael Wing-Yan, Leung, Howard H.W., Chan, Anthony W.H., To, Ka-Fai, Yip, Kevin Yuk-Lap, Lo, Yuk Ming Dennis, Sung, Joseph Jao-Yiu, Cheng, Alfred Sze-Lok
Publicado 2023