dCas9-based gene editing for cleavage-free genomic knock-in of long sequences

por Wang, Chengkun, Qu, Yuanhao, Cheng, Jason K. W., Hughes, Nicholas W., Zhang, Qianhe, Wang, Mengdi, Cong, Le
Publicado 2022

Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects

por Wang, Chengkun, Cheng, Jason K W, Zhang, Qianhe, Hughes, Nicholas W, Xia, Qiong, Winslow, Monte M, Cong, Le
Publicado 2021

CRISPR-Cas12a System With Synergistic Phage Recombination Proteins for Multiplex Precision Editing in Human Cells

por Wang, Chengkun, Xia, Qiong, Zhang, Qianhe, Qu, Yuanhao, Su, Stephen, Cheng, Jason K. W., Hughes, Nicholas W., Cong, Le
Publicado 2022

In Situ Modification of Tissue Stem and Progenitor Cell Genomes

por Goldstein, Jill M., Tabebordbar, Mohammadsharif, Zhu, Kexian, Wang, Leo D., Messemer, Kathleen A., Peacker, Bryan, Kakhki, Sara Ashrafi, Gonzalez-Celeiro, Meryem, Shwartz, Yulia, Cheng, Jason K.W., Xiao, Ru, Barungi, Trisha, Albright, Charles, Hsu, Ya-Chieh, Vandenberghe, Luk H., Wagers, Amy J.
Publicado 2019