Thailandepsin A

por Wang, Cheng, Cheng, Yi-Qiang
Publicado 2011

Thailandepsins are new small molecule class I HDAC inhibitors with potent cytotoxic activity in ovarian cancer cells: a preclinical study of epigenetic ovarian cancer therapy

por Wilson, Andrew J, Cheng, Yi-Qiang, Khabele, Dineo
Publicado 2012

FK228 from Burkholderia thailandensis MSMB43

por Liu, Xiang-Yang, Wang, Cheng, Cheng, Yi-Qiang
Publicado 2012

Cyclo­(-l-prolyl-l-valinyl-) from Burkholderia thailandensis MSMB43

por Liu, Xiang-Yang, Wang, Cheng, Cheng, Yi-Qiang
Publicado 2012

Improved production of cytotoxic thailanstatins A and D through metabolic engineering of Burkholderia thailandensis MSMB43 and pilot scale fermentation

por Liu, Xiangyang, Zhu, Hui, Biswas, Sreya, Cheng, Yi-Qiang
Publicado 2016

The structural basis of an NADP(+)-independent dithiol oxidase in FK228 biosynthesis

por Li, Jie, Wang, Cheng, Zhang, Zhi-Min, Cheng, Yi-Qiang, Zhou, Jiahai
Publicado 2014

Valinomycin Biosynthetic Gene Cluster in Streptomyces: Conservation, Ecology and Evolution

por Matter, Andrea M., Hoot, Sara B., Anderson, Patrick D., Neves, Susana S., Cheng, Yi-Qiang
Publicado 2009

Mechanistic studies of DepR in regulating FK228 biosynthesis in Chromobacterium violaceum no. 968

por Qiao, Yongjian, Tong, Tiantian, Xue, Jiao, Lin, Wenjing, Deng, Zixin, Cheng, Yi-Qiang, Zhu, Dongqing
Publicado 2018

Genomics-guided discovery of a new and significantly better source of anticancer natural drug FK228

por Liu, Xiangyang, Xie, Feng, Doughty, Leah B., Wang, Qi, Zhang, Lixin, Liu, Xueting, Cheng, Yi-Qiang
Publicado 2018

HDAC Inhibitor-Mediated Epigenetic Regulation of Glaucoma-Associated TGFβ2 in the Trabecular Meshwork

por Bermudez, Jaclyn Y., Webber, Hannah C., Patel, Gaurang C., Liu, Xiangyang, Cheng, Yi-Qiang, Clark, Abbot F., Mao, Weiming
Publicado 2016

Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin

por Saraiva, Raúl G., Huitt-Roehl, Callie R., Tripathi, Abhai, Cheng, Yi-Qiang, Bosch, Jürgen, Townsend, Craig A., Dimopoulos, George
Publicado 2018

Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo

por Jang, Samuel, Janssen, Andrew, Aburjania, Zviadi, Robers, Matthew B., Harrison, April, Dammalapati, Ajitha, Cheng, Yi-Qiang, Chen, Herbert, Jaskula-Sztul, Renata
Publicado 2017

Target engagement and drug residence time can be observed in living cells with BRET

por Robers, Matthew B., Dart, Melanie L., Woodroofe, Carolyn C., Zimprich, Chad A., Kirkland, Thomas A., Machleidt, Thomas, Kupcho, Kevin R., Levin, Sergiy, Hartnett, James R., Zimmerman, Kristopher, Niles, Andrew L., Ohana, Rachel Friedman, Daniels, Danette L., Slater, Michael, Wood, Monika G., Cong, Mei, Cheng, Yi-Qiang, Wood, Keith V.
Publicado 2015