Editorial: Beta-Cell Fate: From Gene Circuits to Disease Mechanisms

por Ghila, Luiza, Furuyama, Kenichiro, Grey, Shane T., Scholz, Hanne, Chera, Simona
Publicado 2022

Conversion of Adult Pancreatic α-cells to β-cells After Extreme β-cell Loss

por Thorel, Fabrizio, Népote, Virginie, Avril, Isabelle, Kohno, Kenji, Desgraz, Renaud, Chera, Simona, Herrera, Pedro L.
Publicado 2010

Bioinformatic Analyses of miRNA–mRNA Signature during hiPSC Differentiation towards Insulin-Producing Cells upon HNF4α Mutation

por Ghila, Luiza, Bjørlykke, Yngvild, Legøy, Thomas Aga, Vethe, Heidrun, Furuyama, Kenichiro, Chera, Simona, Ræder, Helge
Publicado 2020

Stage-specific transcriptomic changes in pancreatic α-cells after massive β-cell loss

por Oropeza, Daniel, Cigliola, Valentina, Romero, Agustín, Chera, Simona, Rodríguez-Seguí, Santiago A., Herrera, Pedro L.
Publicado 2021

Modulation of Unfolded Protein Response Restores Survival and Function of β-Cells Exposed to the Endocrine Disruptor Bisphenol A

por Daian, Laura Maria, Tanko, Gabriela, Vacaru, Andrei Mircea, Ghila, Luiza, Chera, Simona, Vacaru, Ana-Maria
Publicado 2023

Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets

por Petrenko, Volodymyr, Sinturel, Flore, Loizides-Mangold, Ursula, Montoya, Jonathan Paz, Chera, Simona, Riezman, Howard, Dibner, Charna
Publicado 2022

Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes

por Bhagchandani, Preksha, Chang, Charles A., Zhao, Weichen, Ghila, Luiza, Herrera, Pedro L., Chera, Simona, Kim, Seung K.
Publicado 2022

Normal Glucagon Signaling and β-Cell Function After Near-Total α-Cell Ablation in Adult Mice

por Thorel, Fabrizio, Damond, Nicolas, Chera, Simona, Wiederkehr, Andreas, Thorens, Bernard, Meda, Paolo, Wollheim, Claes B., Herrera, Pedro L.
Publicado 2011

The core clock transcription factor BMAL1 drives circadian β-cell proliferation during compensatory regeneration of the endocrine pancreas

por Petrenko, Volodymyr, Stolovich-Rain, Miri, Vandereycken, Bart, Giovannoni, Laurianne, Storch, Kai-Florian, Dor, Yuval, Chera, Simona, Dibner, Charna
Publicado 2020

Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells

por Vethe, Heidrun, Bjørlykke, Yngvild, Ghila, Luiza M., Paulo, Joao A., Scholz, Hanne, Gygi, Steven P., Chera, Simona, Ræder, Helge
Publicado 2017

Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors

por Ghila, Luiza, Legøy, Thomas Aga, Mathisen, Andreas Frøslev, Abadpour, Shadab, Paulo, Joao A., Scholz, Hanne, Ræder, Helge, Chera, Simona
Publicado 2021

The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation

por Vethe, Heidrun, Ghila, Luiza, Berle, Magnus, Hoareau, Laurence, Haaland, Øystein A., Scholz, Hanne, Paulo, Joao A., Chera, Simona, Ræder, Helge
Publicado 2019

Reprogrammed Cells Display Distinct Proteomic Signatures Associated with Colony Morphology Variability

por Bjørlykke, Yngvild, Søviknes, Anne M., Hoareau, Laurence, Vethe, Heidrun, Mathisen, Andreas F., Chera, Simona, Vaudel, Marc, Ghila, Luiza M., Ræder, Helge
Publicado 2019

Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling

por Legøy, Thomas Aga, Vethe, Heidrun, Abadpour, Shadab, Strand, Berit L., Scholz, Hanne, Paulo, Joao A., Ræder, Helge, Ghila, Luiza, Chera, Simona
Publicado 2020

Novel protein signatures suggest progression to muscular invasiveness in bladder cancer

por Berle, Magnus, Ghila, Luiza, Vethe, Heidrun, Chaudhry, Adeel, Garberg, Hilde, Beisland, Christian, Haaland, Øystein Ariansen, Oveland, Eystein, Halvorsen, Ole Johan, Davidsson, Thomas, Chera, Simona
Publicado 2018

Diabetes Recovery By Age-Dependent Conversion of Pancreatic δ-Cells Into Insulin Producers

por Chera, Simona, Baronnier, Delphine, Ghila, Luiza, Cigliola, Valentina, Jensen, Jan N., Gu, Guoqiang, Furuyama, Kenichiro, Thorel, Fabrizio, Gribble, Fiona M., Reimann, Frank, Herrera, Pedro L.
Publicado 2014

In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism

por Legøy, Thomas Aga, Mathisen, Andreas F., Salim, Zaidon, Vethe, Heidrun, Bjørlykke, Yngvild, Abadpour, Shadab, Paulo, Joao A., Scholz, Hanne, Ræder, Helge, Ghila, Luiza, Chera, Simona
Publicado 2020

Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells

por Carrasco, Manuel, Wang, Chencheng, Søviknes, Anne M., Bjørlykke, Yngvild, Abadpour, Shadab, Paulo, Joao A., Tjora, Erling, Njølstad, Pål, Ghabayen, Jonas, Nermoen, Ingrid, Lyssenko, Valeriya, Chera, Simona, Ghila, Luiza M., Vaudel, Marc, Scholz, Hanne, Ræder, Helge
Publicado 2022

Diabetes Relief in Mice by Glucose-Sensing Insulin-Secreting Human α-Cells

por Furuyama, Kenichiro, Chera, Simona, van Gurp, Léon, Oropeza, Daniel, Ghila, Luiza, Damond, Nicolas, Vethe, Heidrun, Paulo, Joao A., Joosten, Antoinette M., Berney, Thierry, Bosco, Domenico, Dorrell, Craig, Grompe, Markus, Ræder, Helge, Roep, Bart O., Thorel, Fabrizio, Herrera, Pedro L.
Publicado 2019

Pancreatic Islet-Autonomous Insulin and Smoothened-Mediated Signaling Modulate Identity Changes of Glucagon(+) α-Cells

por Cigliola, Valentina, Ghila, Luiza, Thorel, Fabrizio, van Gurp, Léon, Baronnier, Delphine, Oropeza, Daniel, Gupta, Simone, Miyatsuka, Takeshi, Kaneto, Hideaki, Magnuson, Mark A., Osipovich, Anna B., Sander, Maike, Wright, Christopher V. E., Thomas, Melissa K., Furuyama, Kenichiro, Chera, Simona, Herrera, Pedro L.
Publicado 2018