Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-derived β-Lactone: Selective Crystallization and Formation of a Functional Catalytic Triad in the Active Sit...

por Yin, Jiang, Bergmann, Ernst M., Cherney, Maia M., Lall, Manjinder S., Jain, Rajendra P., Vederas, John C., James, Michael N.G.
Publicado 2005

Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase

por Lee, Ting-Wai, Cherney, Maia M., Liu, Jie, James, Karen Ellis, Powers, James C., Eltis, Lindsay D., James, Michael N.G.
Publicado 2007

A Mechanistic View of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-like Peptidase

por Yin, Jiang, Niu, Chunying, Cherney, Maia M., Zhang, Jianmin, Huitema, Carly, Eltis, Lindsay D., Vederas, John C., James, Michael N.G.
Publicado 2007

Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide

por Lee, Ting-Wai, Cherney, Maia M., Huitema, Carly, Liu, Jie, James, Karen Ellis, Powers, James C., Eltis, Lindsay D., James, Michael N.G.
Publicado 2005

An Episulfide Cation (Thiiranium Ring) Trapped in the Active Site of HAV 3C Proteinase Inactivated by Peptide-based Ketone Inhibitors

por Yin, Jiang, Cherney, Maia M., Bergmann, Ernst M., Zhang, Jianmin, Huitema, Carly, Pettersson, Hanna, Eltis, Lindsay D., Vederas, John C., James, Michael N.G.
Publicado 2006