Activation of Innate Immunity by Therapeutic Nucleic Acids

por Bishani, Ali, Chernolovskaya, Elena L.
Publicado 2021

Current Development of siRNA Bioconjugates: From Research to the Clinic

por Chernikov, Ivan V., Vlassov, Valentin V., Chernolovskaya, Elena L.
Publicado 2019

Structural Modifications of siRNA Improve Its Performance In Vivo

por Chernikov, Ivan V., Ponomareva, Ulyana A., Chernolovskaya, Elena L.
Publicado 2023

A Versatile Solid-Phase Approach to the Synthesis of Oligonucleotide Conjugates with Biodegradable Hydrazone Linker

por Meschaninova, Mariya I., Entelis, Nina S., Chernolovskaya, Elena L., Venyaminova, Alya G.
Publicado 2021

Molecular Mechanism of the Antiproliferative Activity of Short Immunostimulating dsRNA

por Zharkov, Mikhail I., Zenkova, Marina A., Vlassov, Valentin V., Chernolovskaya, Elena L.
Publicado 2019

Novel PEGylated Liposomes Enhance Immunostimulating Activity of isRNA

por Kabilova, Tatyana, Shmendel, Elena, Gladkikh, Daniil, Morozova, Nina, Maslov, Mikhail, Chernolovskaya, Elena, Vlassov, Valentin, Zenkova, Marina
Publicado 2018

Carrier-free cellular uptake and the gene-silencing activity of the lipophilic siRNAs is strongly affected by the length of the linker between siRNA and lipophilic group

por Petrova, Natalya S., Chernikov, Ivan V., Meschaninova, Mariya I., Dovydenko, IIya S., Venyaminova, Aliya G., Zenkova, Marina A., Vlassov, Valentin V., Chernolovskaya, Elena L.
Publicado 2012

Antitumor and Antimetastatic Effect of Small Immunostimulatory RNA against B16 Melanoma in Mice

por Kabilova, Tatyana O., Sen’kova, Aleksandra V., Nikolin, Valeriy P., Popova, Nelly A., Zenkova, Marina A., Vlassov, Valentin V., Chernolovskaya, Elena L.
Publicado 2016

Cholesterol-Containing Nuclease-Resistant siRNA Accumulates in Tumors in a Carrier-free Mode and Silences MDR1 Gene

por Chernikov, Ivan V., Gladkikh, Daniil V., Meschaninova, Mariya I., Ven'yaminova, Alya G., Zenkova, Marina A., Vlassov, Valentin V., Chernolovskaya, Elena L.
Publicado 2017

Trimeric Small Interfering RNAs and Their Cholesterol-Containing Conjugates Exhibit Improved Accumulation in Tumors, but Dramatically Reduced Silencing Activity

por Chernikov, Ivan V., Gladkikh, Daniil V., Karelina, Ulyana A., Meschaninova, Mariya I., Ven’yaminova, Alya G., Vlassov, Valentin V., Chernolovskaya, Elena L.
Publicado 2020

Immunostimulating RNA Delivered by P1500 PEGylated Cationic Liposomes Limits Influenza Infection in C57Bl/6 Mice

por Goncharova, Elena P., Sen‘kova, Aleksandra V., Savin, Innokenty A., Kabilova, Tat‘yana O., Zenkova, Marina A., Vlassov, Valentin V., Chernolovskaya, Elena L.
Publicado 2020

Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA

por Bishani, Ali, Makarova, Darya M., Shmendel, Elena V., Maslov, Mikhail A., Sen‘kova, Aleksandra V., Savin, Innokenty A., Gladkikh, Daniil V., Zenkova, Marina A., Chernolovskaya, Elena L.
Publicado 2023

Transport Oligonucleotides—A Novel System for Intracellular Delivery of Antisense Therapeutics

por Markov, Oleg V., Filatov, Anton V., Kupryushkin, Maxim S., Chernikov, Ivan V., Patutina, Olga A., Strunov, Anton A., Chernolovskaya, Elena L., Vlassov, Valentin V., Pyshnyi, Dmitrii V., Zenkova, Marina A.
Publicado 2020

Immunotherapy of hepatocellular carcinoma with small double-stranded RNA

por Kabilova, Tatyana O, Kovtonyuk, Larisa V, Zonov, Evgeniy V, Ryabchikova, Elena I, Popova, Nelly A, Nikolin, Valeriy P, Kaledin, Vasiliy I, Zenkova, Marina A, Vlassov, Valentin V, Chernolovskaya, Elena L
Publicado 2014

siRNA-Mediated Timp1 Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury

por Chernikov, Ivan V., Staroseletz, Yaroslav Yu., Tatarnikova, Irina S., Sen’kova, Aleksandra V., Savin, Innokenty A., Markov, Andrey V., Logashenko, Evgeniya B., Chernolovskaya, Elena L., Zenkova, Marina A., Vlassov, Valentin V.
Publicado 2023

Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells

por Kupryushkin, Maxim S., Filatov, Anton V., Mironova, Nadezhda L., Patutina, Olga A., Chernikov, Ivan V., Chernolovskaya, Elena L., Zenkova, Marina A., Pyshnyi, Dmitrii V., Stetsenko, Dmitry A., Altman, Sidney, Vlassov, Valentin V.
Publicado 2021

Folate-Equipped Cationic Liposomes Deliver Anti-MDR1-siRNA to the Tumor and Increase the Efficiency of Chemotherapy

por Gladkikh, Daniil V., Sen′kova, Aleksandra V., Chernikov, Ivan V., Kabilova, Tatyana O., Popova, Nelly A., Nikolin, Valery P., Shmendel, Elena V., Maslov, Mikhail A., Vlassov, Valentin V., Zenkova, Marina A., Chernolovskaya, Elena L.
Publicado 2021

Nucleotide Modifications Decrease Innate Immune Response Induced by Synthetic Analogs of snRNAs and snoRNAs

por Stepanov, Grigory, Zhuravlev, Evgenii, Shender, Victoria, Nushtaeva, Anna, Balakhonova, Evgenia, Mozhaeva, Elena, Kasakin, Marat, Koval, Vladimir, Lomzov, Alexander, Pavlyukov, Marat, Malyants, Irina, Zhorov, Mikhail, Kabilova, Tatyana, Chernolovskaya, Elena, Govorun, Vadim, Kuligina, Elena, Semenov, Dmitry, Richter, Vladimir
Publicado 2018

Autocrine-based selection of ligands for personalized CAR-T therapy of lymphoma

por Stepanov, Alexey V., Markov, Oleg V., Chernikov, Ivan V., Gladkikh, Daniil V., Zhang, Hongkai, Jones, Teresa, Sen’kova, Alexandra V., Chernolovskaya, Elena L., Zenkova, Marina A., Kalinin, Roman S., Rubtsova, Maria P., Meleshko, Alexander N., Genkin, Dmitry D., Belogurov, Alexey A., Xie, Jia, Gabibov, Alexander G., Lerner, Richard A.
Publicado 2018