CRAFTing a New Approach to Antiepileptic Drug Discovery

por Lyman, Kyle A., Chetkovich, Dane M.
Publicado 2019

PUMILIO1 Links Epilepsy to Spinocerebellar Ataxia

por Lyman, Kyle A., Chetkovich, Dane M.
Publicado 2019

Oligodendrocyte K(ir)4.1 Channels Clear Out Congested K(+)

por Lyman, Kyle A., Chetkovich, Dane M.
Publicado 2019

Moving Metabolism to Make Inroads in a Model of Mitochondrial Epilepsy

por Lyman, Kyle A., Chetkovich, Dane M.
Publicado 2019

BACE1(-/- )mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization

por Hitt, Brian D, Jaramillo, Thomas C, Chetkovich, Dane M, Vassar, Robert
Publicado 2010

The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels

por Han, Ye, Lyman, Kyle A., Foote, Kendall M., Chetkovich, Dane M.
Publicado 2020

Loss of HCN2 leads to delayed gastrointestinal motility and reduced energy intake in mice

por Fisher, Daniel W., Luu, Phillip, Agarwal, Neha, Kurz, Jonathan E., Chetkovich, Dane M.
Publicado 2018

Entorhinal velocity signals reflect environmental geometry

por Munn, Robert G K, Mallory, Caitlin S, Hardcastle, Kiah, Chetkovich, Dane M, Giocomo, Lisa M
Publicado 2020

TRIP8b Is Required for Maximal Expression of HCN1 in the Mouse Retina

por Pan, Yuan, Bhattarai, Sajag, Modestou, Modestos, Drack, Arlene V., Chetkovich, Dane M., Baker, Sheila A.
Publicado 2014

HCN channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects

por Han, Ye, Heuermann, Robert J., Lyman, Kyle A., Fisher, Daniel, Ismail, Quratul-Ain, Chetkovich, Dane M.
Publicado 2016

Excitatory Synaptic Input to Hilar Mossy Cells under Basal and Hyperexcitable Conditions

por Hedrick, Tristan P., Nobis, William P., Foote, Kendall M., Ishii, Toshiyuki, Chetkovich, Dane M., Swanson, Geoffrey T.
Publicado 2017

Dual Palmitoylation of Psd-95 Mediates Its Vesiculotubular Sorting, Postsynaptic Targeting, and Ion Channel Clustering

por El-Husseini, Alaa E., Craven, Sarah E., Chetkovich, Dane M., Firestein, Bonnie L., Schnell, Eric, Aoki, Chiye, Bredt, David S.
Publicado 2000

Enhanced Synaptic Transmission in the Extended Amygdala and Altered Excitability in an Extended Amygdala to Brainstem Circuit in a Dravet Syndrome Mouse Model

por Yan, Wen Wei, Xia, Maya, Chiang, Jeremy, Levitt, Alyssa, Hawkins, Nicole, Kearney, Jennifer, Swanson, Geoffrey T., Chetkovich, Dane, Nobis, William P.
Publicado 2021

Regulation of Axonal HCN1 Trafficking in Perforant Path Involves Expression of Specific TRIP8b Isoforms

por Wilkars, Wiebke, Liu, Zhiqiang, Lewis, Alan S., Stoub, Travis R., Ramos, Elena M., Brandt, Nicola, Nicholson, Daniel A., Chetkovich, Dane M., Bender, Roland A.
Publicado 2012

Characterization of the HCN Interaction Partner TRIP8b/PEX5R in the Intracardiac Nervous System of TRIP8b-Deficient and Wild-Type Mice

por Scherschel, Katharina, Bräuninger, Hanna, Mölders, Andrea, Erlenhardt, Nadine, Amin, Ehsan, Jungen, Christiane, Pape, Ulrike, Lindner, Diana, Chetkovich, Dane M., Klöcker, Nikolaj, Meyer, Christian
Publicado 2021

Modulation of thalamocortical oscillations by TRIP8b, an auxiliary subunit for HCN channels

por Zobeiri, Mehrnoush, Chaudhary, Rahul, Datunashvili, Maia, Heuermann, Robert J., Lüttjohann, Annika, Narayanan, Venu, Balfanz, Sabine, Meuth, Patrick, Chetkovich, Dane M., Pape, Hans-Christian, Baumann, Arnd, van Luijtelaar, Gilles, Budde, Thomas
Publicado 2017

Modulation of pacemaker channel function in a model of thalamocortical hyperexcitability by demyelination and cytokines

por Chaudhary, Rahul, Albrecht, Stefanie, Datunashvili, Maia, Cerina, Manuela, Lüttjohann, Annika, Han, Ye, Narayanan, Venu, Chetkovich, Dane M, Ruck, Tobias, Kuhlmann, Tanja, Pape, Hans-Christian, Meuth, Sven G, Zobeiri, Mehrnoush, Budde, Thomas
Publicado 2022

Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons

por Han, Ye, Iyamu, Iredia D., Clutter, Matthew R., Mishra, Rama K., Lyman, Kyle A., Zhou, Chengwen, Michailidis, Ioannis, Xia, Maya Y., Sharma, Horrick, Luan, Chi-Hao, Schiltz, Gary E., Chetkovich, Dane M.
Publicado 2022

HCN Channelopathy in External Globus Pallidus Neurons in Models of Parkinson’s Disease

por Chan, C. Savio, Glajch, Kelly E., Gertler, Tracy S., Guzman, Jaime N., Mercer, Jeff N., Lewis, Alan S., Goldberg, Alan B., Tkatch, Tatiana, Shigemoto, Ryuichi, Fleming, Sheila M., Chetkovich, Dane M., Osten, Pavel, Kita, Hitoshi, Surmeier, D. James
Publicado 2010

Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive

por Yun, Sanghee, Reynolds, Ryan P., Petrof, Iraklis, White, Alicia, Rivera, Phillip D., Segev, Amir, Gibson, Adam D., Suarez, Maiko, Desalle, Matthew J., Ito, Naoki, Mukherjee, Shibani, Richardson, Devon R., Kang, Catherine E., Ahrens-Nicklas, Rebecca C., Soler, Ivan, Chetkovich, Dane M., Kourrich, Saïd, Coulter, Douglas A., Eisch, Amelia J.
Publicado 2018