TRIM16 inhibits neuroblastoma cell proliferation through cell cycle regulation and dynamic nuclear localization

por Bell, Jessica L., Malyukova, Alena, Kavallaris, Maria, Marshall, Glenn M., Cheung, Belamy B.
Publicado 2013

Synthesis, Characterization and Biological Evaluation of Novel Dihydropyranoindoles Improving the Anticancer Effects of HDAC Inhibitors

por Bingul, Murat, Arndt, Greg M., Marshall, Glenn M., Cheung, Belamy B., Kumar, Naresh, Black, David StC.
Publicado 2020

Synthesis and Characterisation of Novel Tricyclic and Tetracyclic Furoindoles: Biological Evaluation as SAHA Enhancer against Neuroblastoma and Breast Cancer Cells

por Bingul, Murat, Arndt, Greg M., Marshall, Glenn M., Black, David StC., Cheung, Belamy B., Kumar, Naresh
Publicado 2021

TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells

por Kim, Patrick Y., Rahmanto, Aldwin Suryo, Tan, Owen, Norris, Murray D., Haber, Michelle, Marshall, Glenn M., Cheung, Belamy B.
Publicado 2013

Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis

por Sutton, Selina K., Cheung, Belamy B., Massudi, Hassina, Tan, Owen, Koach, Jessica, Mayoh, Chelsea, Carter, Daniel R., Marshall, Glenn M.
Publicado 2019

TRIM16 Acts as an E3 Ubiquitin Ligase and Can Heterodimerize with Other TRIM Family Members

por Bell, Jessica L., Malyukova, Alena, Holien, Jessica K., Koach, Jessica, Parker, Michael W., Kavallaris, Maria, Marshall, Glenn M., Cheung, Belamy B.
Publicado 2012

Withaferin A activates TRIM16 for its anti-cancer activity in melanoma

por Nagy, Zsuzsanna, Cheung, Belamy B., Tsang, Wing, Tan, Owen, Herath, Mika, Ciampa, Olivia C., Shadma, Fatima, Carter, Daniel R., Marshall, Glenn M.
Publicado 2020

Increase in DNA Damage by MYCN Knockdown Through Regulating Nucleosome Organization and Chromatin State in Neuroblastoma

por Hu, Xinjie, Zheng, Weisheng, Zhu, Qianshu, Gu, Liang, Du, Yanhua, Han, Zhe, Zhang, Xiaobai, Carter, Daniel R., Cheung, Belamy B., Qiu, Andong, Jiang, Cizhong
Publicado 2019

Synthesis, Characterization and Anti-Cancer Activity of Hydrazide Derivatives Incorporating a Quinoline Moiety

por Bingul, Murat, Tan, Owen, Gardner, Christopher R., Sutton, Selina K., Arndt, Greg M., Marshall, Glenn M., Cheung, Belamy B., Kumar, Naresh, Black, David StC.
Publicado 2016

MYCN-targeting miRNAs are predominantly downregulated during MYCN-driven neuroblastoma tumor formation

por Beckers, Anneleen, Van Peer, Gert, Carter, Daniel R., Mets, Evelien, Althoff, Kristina, Cheung, Belamy B., Schulte, Johannes H., Mestdagh, Pieter, Vandesompele, Jo, Marshall, Glenn M., De Preter, Katleen, Speleman, Frank
Publicado 2014

The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression

por Tee, Andrew E., Liu, Bing, Song, Renhua, Li, Jinyan, Pasquier, Eddy, Cheung, Belamy B., Jiang, Cizhong, Marshall, Glenn M., Haber, Michelle, Norris, Murray D., Fletcher, Jamie I., Dinger, Marcel E., Liu, Tao
Publicado 2016

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner

por Sutton, Selina K., Carter, Daniel R., Kim, Patrick, Tan, Owen, Arndt, Greg M., Zhang, Xu Dong, Baell, Jonathan, Noll, Benjamin D., Wang, Shudong, Kumar, Naresh, McArthur, Grant A., Cheung, Belamy B., Marshall, Glenn M.
Publicado 2016

An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability

por Nagy, Zsuzsanna, Seneviratne, Janith A., Kanikevich, Maxwell, Chang, William, Mayoh, Chelsea, Venkat, Pooja, Du, Yanhua, Jiang, Cizhong, Salib, Alice, Koach, Jessica, Carter, Daniel R., Mittra, Rituparna, Liu, Tao, Parker, Michael W., Cheung, Belamy B., Marshall, Glenn M.
Publicado 2021

Inhibitors of the Oncogenic PA2G4-MYCN Protein-Protein Interface

por Massudi, Hassina, Luo, Jie-Si, Holien, Jessica K., Gadde, Satyanarayana, Krishan, Sukriti, Herath, Mika, Koach, Jessica, Stevenson, Brendan W., Gorman, Michael A., Venkat, Pooja, Mayoh, Chelsea, Luo, Xue-Qun, Parker, Michael W., Cheung, Belamy B., Marshall, Glenn M.
Publicado 2023

MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4

por Xue, Chengyuan, Yu, Denise M.T., Gherardi, Samuele, Koach, Jessica, Milazzo, Giorgio, Gamble, Laura, Liu, Bing, Valli, Emanuele, Russell, Amanda J., London, Wendy B., Liu, Tao, Cheung, Belamy B., Marshall, Glenn M., Perini, Giovanni, Haber, Michelle, Norris, Murray D.
Publicado 2016

Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma

por Zhai, Lei, Balachandran, Anushree, Larkin, Rebecca, Seneviratne, Janith A., Chung, Sylvia A., Lalwani, Amit, Tsubota, Shoma, Beck, Dominik, Kadomatsu, Kenji, Beckers, Anneleen, Durink, Kaat, De Preter, Katleen, Speleman, Frank, Haber, Michelle, Norris, Murray D., Swarbrick, Alexander, Cheung, Belamy B., Marshall, Glenn M., Carter, Daniel R.
Publicado 2023

TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells

por Sutton, Selina K., Koach, Jessica, Tan, Owen, Liu, Bing, Carter, Daniel R., Wilmott, James S., Yosufi, Benafsha, Haydu, Lauren E., Mann, Graham J., Thompson, John F., Long, Georgina V., Liu, Tao, McArthur, Grant, Zhang, Xu Dong, Scolyer, Richard A., Cheung, Belamy B., Marshall, Glenn M.
Publicado 2014

MEIS2 Is an Adrenergic Core Regulatory Transcription Factor Involved in Early Initiation of TH-MYCN-Driven Neuroblastoma Formation

por De Wyn, Jolien, Zimmerman, Mark W., Weichert-Leahey, Nina, Nunes, Carolina, Cheung, Belamy B., Abraham, Brian J., Beckers, Anneleen, Volders, Pieter-Jan, Decaesteker, Bieke, Carter, Daniel R., Look, Alfred Thomas, De Preter, Katleen, Van Loocke, Wouter, Marshall, Glenn M., Durbin, Adam D., Speleman, Frank, Durinck, Kaat
Publicado 2021

The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro

por Cheung, Belamy B, Koach, Jessica, Tan, Owen, Kim, Patrick, Bell, Jessica L, D'andreti, Carla, Sutton, Selina, Malyukova, Alena, Sekyere, Eric, Norris, Murray, Haber, Michelle, Kavallaris, Maria, Cunningham, Anne M, Proby, Charlotte, Leigh, Irene, Wilmott, James S, Cooper, Caroline L, Halliday, Gary M, Scolyer, Richard A, Marshall, Glenn M
Publicado 2012

The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression

por Xiao, Lin, Karsa, Mawar, Ronca, Emma, Bongers, Angelika, Kosciolek, Angelika, El-Ayoubi, Ali, Revalde, Jezrael L., Seneviratne, Janith A., Cheung, Belamy B., Cheung, Laurence C., Kotecha, Rishi S., Newbold, Andrea, Bjelosevic, Stefan, Arndt, Greg M., Lock, Richard B., Johnstone, Ricky W., Gudkov, Andrei V., Gurova, Katerina V., Haber, Michelle, Norris, Murray D., Henderson, Michelle J., Somers, Klaartje
Publicado 2022