Modulation of intracellular ROS levels by TIGAR controls autophagy

por Bensaad, Karim, Cheung, Eric C, Vousden, Karen H
Publicado 2009

TIGAR, TIGAR, burning bright

por Lee, Pearl, Vousden, Karen H, Cheung, Eric C
Publicado 2014

The Regulation of TIGAR

por Lee, Pearl, Cheung, Eric C, Vousden, Karen H
Publicado 2014

iRFP Is a Real Time Marker for Transformation Based Assays in High Content Screening

por Paulus-Hock, Viola, Cheung, Eric C., Roxburgh, Patricia, Vousden, Karen H., Hock, Andreas K.
Publicado 2014

Cell Clustering Promotes a Metabolic Switch that Supports Metastatic Colonization

por Labuschagne, Christiaan F., Cheung, Eric C., Blagih, Julianna, Domart, Marie-Charlotte, Vousden, Karen H.
Publicado 2019

Metabolic Regulation by p53 Family Members

por Berkers, Celia R., Maddocks, Oliver D.K., Cheung, Eric C., Mor, Inbal, Vousden, Karen H.
Publicado 2013

The in vivo function of the p53 target gene TIGAR

por Cheung, Eric C, Athineos, Dimitris, Ridgway, Rachel, Blyth, Karen, Strathdee, Douglas, Sansom, Owen, Vousden, Karen H
Publicado 2012

Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine

por Cheung, Eric C., Lee, Pearl, Ceteci, Fatih, Nixon, Colin, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
Publicado 2016

Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer

por Cheung, Eric C., DeNicola, Gina M., Nixon, Colin, Blyth, Karen, Labuschagne, Christiaan F., Tuveson, David A., Vousden, Karen H.
Publicado 2020

The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells

por Hennequart, Marc, Labuschagne, Christiaan F., Tajan, Mylène, Pilley, Steven E., Cheung, Eric C., Legrave, Nathalie M., Driscoll, Paul C., Vousden, Karen H.
Publicado 2021

TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis

por Cheung, Eric C., Athineos, Dimitris, Lee, Pearl, Ridgway, Rachel A., Lambie, Wendy, Nixon, Colin, Strathdee, Douglas, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
Publicado 2013

Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo

por Hock, Andreas K., Cheung, Eric C., Humpton, Timothy J., Monteverde, Tiziana, Paulus-Hock, Viola, Lee, Pearl, McGhee, Ewan, Scopelliti, Alessandro, Murphy, Daniel J., Strathdee, Douglas, Blyth, Karen, Vousden, Karen H.
Publicado 2017

β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle

por Parker, Brian A., Walton, Chase M., Carr, Sheryl T., Andrus, Jacob L., Cheung, Eric C. K., Duplisea, Michael J., Wilson, Esther K., Draney, Carrie, Lathen, Daniel R., Kenner, Kyle B., Thomson, David M., Tessem, Jeffery S., Bikman, Benjamin T.
Publicado 2018

The dietary sweetener sucralose is a negative modulator of T cell-mediated responses

por Zani, Fabio, Blagih, Julianna, Gruber, Tim, Buck, Michael D., Jones, Nicholas, Hennequart, Marc, Newell, Clare L., Pilley, Steven E., Soro-Barrio, Pablo, Kelly, Gavin, Legrave, Nathalie M., Cheung, Eric C., Gilmore, Ian S., Gould, Alex P., Garcia-Caceres, Cristina, Vousden, Karen H.
Publicado 2023

PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma

por D’Avola, Annalisa, Legrave, Nathalie, Tajan, Mylène, Chakravarty, Probir, Shearer, Ryan L., King, Hamish W., Kluckova, Katarina, Cheung, Eric C., Clear, Andrew J., Gunawan, Arief S., Zhang, Lingling, James, Louisa K., MacRae, James I., Gribben, John G., Calado, Dinis P., Vousden, Karen H., Riches, John C.
Publicado 2022

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

por Tajan, Mylène, Hennequart, Marc, Cheung, Eric C., Zani, Fabio, Hock, Andreas K., Legrave, Nathalie, Maddocks, Oliver D. K., Ridgway, Rachel A., Athineos, Dimitris, Suárez-Bonnet, Alejandro, Ludwig, Robert L., Novellasdemunt, Laura, Angelis, Nikolaos, Li, Vivian S. W., Vlachogiannis, Georgios, Valeri, Nicola, Mainolfi, Nello, Suri, Vipin, Friedman, Adam, Manfredi, Mark, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
Publicado 2021