Current Landscape of Heart Failure Gene Therapy

por Kieserman, Jake M., Myers, Valerie D., Dubey, Praveen, Cheung, Joseph Y., Feldman, Arthur M.
Publicado 2019

Role of Bcl2-associated Athanogene 3 in Turnover of Gap Junction Protein, Connexin 43, in Neonatal Cardiomyocytes

por Ghasemi Tahrir, Farzaneh, Gupta, Manish, Myers, Valerie, Gordon, Jennifer, Cheung, Joseph Y., Feldman, Arthur M., Khalili, Kamel
Publicado 2019

The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression

por Bao, Lei, Festa, Fernanda, Hirschler-Laszkiewicz, Iwona, Keefer, Kerry, Wang, Hong-Gang, Cheung, Joseph Y., Miller, Barbara A.
Publicado 2022

Lamin B is a target for selective nuclear PQC by BAG3: implication for nuclear envelopathies

por Gupta, Manish K., Gordon, Jennifer, Glauser, Gregory M., Myers, Valerie D., Feldman, Arthur M., Cheung, Joseph Y., Khalili, Kamel
Publicado 2019

HIV-1 Nef-induced cardiotoxicity through dysregulation of autophagy

por Gupta, Manish K., Kaminski, Rafal, Mullen, Brian, Gordon, Jennifer, Burdo, Tricia H., Cheung, Joseph Y., Feldman, Arthur M., Madesh, Muniswamy, Khalili, Kamel
Publicado 2017

BAG3: a new player in the heart failure paradigm

por Knezevic, Tijana, Myers, Valerie D., Gordon, Jennifer, Tilley, Douglas G., Sharp, Thomas E., Wang, JuFang, Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.
Publicado 2015

The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation

por Hirschler-Laszkiewicz, Iwona, Chen, Shu-jen, Bao, Lei, Wang, JuFang, Zhang, Xue-Qian, Shanmughapriya, Santhanam, Keefer, Kerry, Madesh, Muniswamy, Cheung, Joseph Y., Miller, Barbara A.
Publicado 2018

Mitochondrial Magnesium is the cationic rheostat for MCU-mediated mitochondrial Ca(2+) uptake

por Ponnusamy, Thiruvelselvan, Velusamy, Prema, Kumar, Amrendra, Morris, Daniel, Zhang, Xueqian, Ning, Gang, Klinger, Marianne, Copper, Jean E., Rajan, Sudarsan, Cheung, Joseph Y, Natarajaseenivasan, Kalimuthusamy, Mnatsakanyan, Nelli, Shanmughapriya, Santhanam
Publicado 2023

Cardioprotection of Controlled and Cardiac-Specific Over-Expression of A(2A)-Adenosine Receptor in the Pressure Overload

por Hamad, Eman A., Zhu, Weizhong, Chan, Tung O., Myers, Valerie, Gao, Erhe, Li, Xue, Zhang, Jin, Song, Jianliang, Zhang, Xue-Qian, Cheung, Joseph Y., Koch, Walter, Feldman, Arthur M.
Publicado 2012

The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease

por Myers, Valerie D., McClung, Joseph M., Wang, JuFang, Tahrir, Farzaneh G., Gupta, Manish K., Gordon, Jennifer, Kontos, Christopher H., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.
Publicado 2018

The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1

por Hirschler-Laszkiewicz, Iwona, Festa, Fernanda, Huang, Suming, Moldovan, George-Lucian, Nicolae, Claudia, Dhoonmoon, Ashna, Bao, Lei, Keefer, Kerry, Chen, Shu-jen, Wang, Hong-Gang, Cheung, Joseph Y., Miller, Barbara A.
Publicado 2022

The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2

por Bao, Lei, Festa, Fernanda, Freet, Christopher S., Lee, John P., Hirschler-Laszkiewicz, Iwona M., Chen, Shu-jen, Keefer, Kerry A., Wang, Hong-Gang, Patterson, Andrew D., Cheung, Joseph Y., Miller, Barbara A.
Publicado 2019

BAG3: Nature’s Quintessential Multi-Functional Protein Functions as a Ubiquitous Intra-Cellular Glue

por Brenner, Caitlyn M., Choudhary, Muaaz, McCormick, Michael G., Cheung, David, Landesberg, Gavin P., Wang, Ju-Fang, Song, Jianliang, Martin, Thomas G., Cheung, Joseph Y., Qu, Hui-Qi, Hakonarson, Hakon, Feldman, Arthur M.
Publicado 2023

SLC25A23 augments mitochondrial Ca(2+) uptake, interacts with MCU, and induces oxidative stress–mediated cell death

por Hoffman, Nicholas E., Chandramoorthy, Harish C., Shanmughapriya, Santhanam, Zhang, Xueqian Q., Vallem, Sandhya, Doonan, Patrick J., Malliankaraman, Karthik, Guo, Shuchi, Rajan, Sudarsan, Elrod, John W., Koch, Walter J., Cheung, Joseph Y., Madesh, Muniswamy
Publicado 2014

Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy

por Chen, Shu-jen, Bao, Lei, Keefer, Kerry, Shanmughapriya, Santhanam, Chen, Longgui, Lee, John, Wang, JuFang, Zhang, Xue-Qian, Hirschler-Laszkiewicz, Iwona, Merali, Salim, Merali, Carmen, Imamura, Yuka, Dovat, Sinisa, Madesh, Muniswamy, Cheung, Joseph Y., Wang, Hong-Gang, Miller, Barbara A.
Publicado 2020

Adeno-Associated Virus Serotype 9–Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts With Left Ventricular Dysfunction Secondary to a Myocardial Infarcti...

por Knezevic, Tijana, Myers, Valerie D., Su, Feifei, Wang, JuFang, Song, Jianliang, Zhang, Xue-Qian, Gao, Erhe, Gao, Guofeng, Madesh, Muniswamy, Gupta, Manish K., Gordon, Jennifer, Weiner, Kristen N., Rabinowitz, Joseph, Ramsey, Frederick V., Tilley, Douglas G., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.
Publicado 2016

Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart

por Wang, JuFang, Tomar, Dhadendra, Martin, Thomas G., Dubey, Shubham, Dubey, Praveen K., Song, Jianliang, Landesberg, Gavin, McCormick, Michael G., Myers, Valerie D., Merali, Salim, Merali, Carmen, Lemster, Bonnie, McTiernan, Charles F., Khalili, Kamel, Madesh, Muniswamy, Cheung, Joseph Y., Kirk, Jonathan A., Feldman, Arthur M.
Publicado 2023