Analyzing and Quantifying the Gain-of-Function Enhancement of IP(3) Receptor Gating by Familial Alzheimer’s Disease-Causing Mutants in Presenilins

por Mak, Don-On Daniel, Cheung, King-Ho, Toglia, Patrick, Foskett, J. Kevin, Ullah, Ghanim
Publicado 2015

InsP(3)R-SEC5 interaction on phagosomes modulates innate immunity to Candida albicans by promoting cytosolic Ca(2+) elevation and TBK1 activity

por Yang, Long, Gu, Wenwen, Cheung, King-Ho, Yan, Lan, Tong, Benjamin Chun-Kit, Jiang, Yuanying, Yang, Jun
Publicado 2018

Correction to: InsP(3)R-SEC5 interaction on phagosomes modulates innate immunity to Candida albicans by promoting cytosolic Ca (2+) elevation and TBK1 activity

por Yang, Long, Gu, Wenwen, Cheung, King-Ho, Yan, Lan, Tong, Benjamin Chun-Kit, Jiang, Yuanying, Yang, Jun
Publicado 2020

Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells

por Bozym, Rebecca A., Patel, Kunal, White, Carl, Cheung, King-Ho, Bergelson, Jeffrey M., Morosky, Stefanie A., Coyne, Carolyn B.
Publicado 2011

Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology

por Lee, Claire Shuk-Kwan, Tong, Benjamin Chun-Kit, Cheng, Cecily Wing-Hei, Hung, Harry Chun-Hin, Cheung, King-Ho
Publicado 2016

Mode Switching Is the Major Mechanism of Ligand Regulation of InsP(3) Receptor Calcium Release Channels

por Ionescu, Lucian, White, Carl, Cheung, King-Ho, Shuai, Jianwei, Parker, Ian, Pearson, John E., Foskett, J. Kevin, Mak, Don-On Daniel
Publicado 2007

Cell–cell Interaction Underlies Formation of Fluid in the Male Reproductive Tract of the Rat

por Cheung, King-ho, Leung, George P.H., Leung, Matthew C.T., Shum, Winnie W.C., Zhou, Wen-liang, Wong, Patrick Y.D.
Publicado 2005

Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer’s Disease

por Guan, Xinjie, Iyaswamy, Ashok, Sreenivasmurthy, Sravan Gopalkrishnashetty, Su, Chengfu, Zhu, Zhou, Liu, Jia, Kan, Yuxuan, Cheung, King-Ho, Lu, Jiahong, Tan, Jieqiong, Li, Min
Publicado 2022

Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A

por Lu, Yingying, Dong, Shichen, Hao, Baixia, Li, Chang, Zhu, Kaiyuan, Guo, Wenjing, Wang, Qian, Cheung, King-Ho, Wong, Connie WM, Wu, Wu-Tian, Markus, Huss, Yue, Jianbo
Publicado 2014

Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson’s Disease

por Zhu, Zhou, Yang, Chuanbin, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Liu, Jia, Wang, Ziying, Tong, Benjamin Chun-Kit, Song, Juxian, Lu, Jiahong, Cheung, King-Ho, Li, Min
Publicado 2019

Exploring the Potential of Aptamers in Targeting Neuroinflammation and Neurodegenerative Disorders: Opportunities and Challenges

por Kong, Anna Hau-Yee, Wu, Aston Jiaxi, Ho, Olivia Ka-Yi, Leung, Maggie Ming-Ki, Huang, Alexis Shiying, Yu, Yuanyuan, Zhang, Ge, Lyu, Aiping, Li, Min, Cheung, King-Ho
Publicado 2023

A Curcumin Derivative Activates TFEB and Protects Against Parkinsonian Neurotoxicity in Vitro

por Wang, Ziying, Yang, Chuanbin, Liu, Jia, Chun-Kit Tong, Benjamin, Zhu, Zhou, Malampati, Sandeep, Gopalkrishnashetty Sreenivasmurthy, Sravan, Cheung, King-Ho, Iyaswamy, Ashok, Su, Chengfu, Lu, Jiahong, Song, Juxian, Li, Min
Publicado 2020

A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38

por Yang, Chuanbin, Zhu, Zhou, Tong, Benjamin Chun-Kit, Iyaswamy, Ashok, Xie, Wen-Jian, Zhu, Yu, Sreenivasmurthy, Sravan Gopalkrishnashetty, Senthilkumar, Krishnamoorthi, Cheung, King-Ho, Song, Ju-Xian, Zhang, Hong-Jie, Li, Min
Publicado 2020

Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies

por Tong, Benjamin Chun-Kit, Huang, Alexis Shiying, Wu, Aston Jiaxi, Iyaswamy, Ashok, Ho, Olivia Ka-Yi, Kong, Anna Hau-Yee, Sreenivasmurthy, Sravan Gopalkrishnashetty, Zhu, Zhou, Su, Chengfu, Liu, Jia, Song, Juxian, Li, Min, Cheung, King-Ho
Publicado 2022

Targeting Aggrephagy for the Treatment of Alzheimer’s Disease

por Malampati, Sandeep, Song, Ju-Xian, Chun-Kit Tong, Benjamin, Nalluri, Anusha, Yang, Chuan-Bin, Wang, Ziying, Gopalkrishnashetty Sreenivasmurthy, Sravan, Zhu, Zhou, Liu, Jia, Su, Chengfu, Krishnamoorthi, Senthilkumar, Iyaswamy, Ashok, Cheung, King-Ho, Lu, Jia-Hong, Li, Min
Publicado 2020

A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models

por Song, Ju‐Xian, Malampati, Sandeep, Zeng, Yu, Durairajan, Siva Sundara Kumar, Yang, Chuan‐Bin, Tong, Benjamin Chun‐Kit, Iyaswamy, Ashok, Shang, Wen‐Bin, Sreenivasmurthy, Sravan Gopalkrishnashetty, Zhu, Zhou, Cheung, King‐Ho, Lu, Jia‐Hong, Tang, Chunzhi, Xu, Nenggui, Li, Min
Publicado 2019

Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer’s disease

por Iyaswamy, Ashok, Thakur, Abhimanyu, Guan, Xin-Jie, Krishnamoorthi, Senthilkumar, Fung, Tsz Yan, Lu, Kejia, Gaurav, Isha, Yang, Zhijun, Su, Cheng-Fu, Lau, Kwok-Fai, Zhang, Kui, Ng, Roy Chun-Laam, Lian, Qizhou, Cheung, King-Ho, Ye, Keqiang, Chen, Huanhuan Joyce, Li, Min
Publicado 2023

Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models

por Iyaswamy, Ashok, Wang, Xueli, Krishnamoorthi, Senthilkumar, Kaliamoorthy, Venkatapathy, Sreenivasmurthy, Sravan G., Kumar Durairajan, Siva Sundara, Song, Ju-Xian, Tong, Benjamin Chun-kit, Zhu, Zhou, Su, Cheng-Fu, Liu, Jia, Cheung, King-Ho, Lu, Jia-Hong, Tan, Jie-Qiong, Li, Hung Wing, Wong, Man Shing, Li, Min
Publicado 2022

Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy

por Sreenivasmurthy, Sravan Gopalkrishnashetty, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Reddi, Rambabu N., Kammala, Ananth Kumar, Vasudevan, Karthick, Senapati, Sanjib, Zhu, Zhou, Su, Cheng-Fu, Liu, Jia, Guan, Xin-Jie, Chua, Ka-Kit, Cheung, King-Ho, Chen, Hubiao, Zhang, Hong-Jie, Zhang, Yuan, Song, Ju-Xian, Kumar Durairajan, Siva Sundara, Li, Min
Publicado 2022