Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity

por Zhao, Xinbin, Sun, Kun, Lan, Zhou, Song, Wenxin, Cheng, Lili, Chi, Wenna, Chen, Jing, Huo, Yi, Xu, Lina, Liu, Xiaohui, Deng, Haiteng, Siegenthaler, Julie A., Chen, Ligong
Publicado 2017

Hepatic mitochondrial NAD(+) transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis

por Cheng, Lili, Deepak, R.N.V. Krishna, Wang, Guoqiang, Meng, Ziyi, Tao, Lei, Xie, Mengqing, Chi, Wenna, Zhang, Yuming, Yang, Mingming, Liao, Yilie, Chen, Ruiqun, Liang, Yu, Zhang, Junyu, Huang, Yuedong, Wang, Weihua, Guo, Zhiying, Wang, Yunfang, Lin, Jiandie D., Fan, Hao, Chen, Ligong
Publicado 2023

Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity

por Cheng, Lili, Ge, Mengmeng, Lan, Zhou, Ma, Zhilong, Chi, Wenna, Kuang, Wenhua, Sun, Kun, Zhao, Xinbin, Liu, Ye, Feng, Yaqian, Huang, Yuedong, Luo, Maoguo, Li, Liping, Zhang, Bin, Hu, Xiaoyu, Xu, Lina, Liu, Xiaohui, Huo, Yi, Deng, Haiteng, Yang, Jinliang, Xi, Qiaoran, Zhang, Yonghui, Siegenthaler, Julie A., Chen, Ligong
Publicado 2017

Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans

por Che, Li, Chi, Wenna, Qiao, Yu, Zhang, Jie, Song, Xinhua, Liu, Ye, Li, Lei, Jia, Jiaoyuan, Pilo, Maria G, Wang, Jingxiao, Cigliano, Antonio, Ma, Zhilong, Kuang, Wenhua, Tang, Zefang, Zhang, Zemin, Shui, Guanghou, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Pascale, Rosa Maria, Cossu, Carla, Pes, Giovanni Mario, Osborne, Timothy F, Calvisi, Diego F, Chen, Xin, Chen, Ligong
Publicado 2020