Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2

por Liu, Qian, Osterlund, Elizabeth J, Chi, Xiaoke, Pogmore, Justin, Leber, Brian, Andrews, David William
Publicado 2019

The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

por Chi, Xiaoke, Nguyen, Dang, Pemberton, James M, Osterlund, Elizabeth J, Liu, Qian, Brahmbhatt, Hetal, Zhang, Zhi, Lin, Jialing, Leber, Brian, Andrews, David W
Publicado 2020

TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL

por Thébault, Stéphanie, Agez, Morgane, Chi, Xiaoke, Stojko, Johann, Cura, Vincent, Telerman, Stéphanie B., Maillet, Laurent, Gautier, Fabien, Billas-Massobrio, Isabelle, Birck, Catherine, Troffer-Charlier, Nathalie, Karafin, Teele, Honoré, Joane, Senff-Ribeiro, Andrea, Montessuit, Sylvie, Johnson, Christopher M., Juin, Philippe, Cianférani, Sarah, Martinou, Jean-Claude, Andrews, David W., Amson, Robert, Telerman, Adam, Cavarelli, Jean
Publicado 2016