The Opportunities and Challenges of Integrating Population Histories Into Genetic Studies for Diverse Populations: A Motivating Example From Native Hawaiians

por Chiang, Charleston W. K.
Publicado 2021

Conflation of Short Identity-by-Descent Segments Bias Their Inferred Length Distribution

por Chiang, Charleston W. K., Ralph, Peter, Novembre, John
Publicado 2016

KLFDAPC: a supervised machine learning approach for spatial genetic structure analysis

por Qin, Xinghu, Chiang, Charleston W K, Gaggiotti, Oscar E
Publicado 2022

Deciphering signatures of natural selection via deep learning

por Qin, Xinghu, Chiang, Charleston W K, Gaggiotti, Oscar E
Publicado 2022

Recombination map tailored to Native Hawaiians improves robustness of genomic scans for positive selection

por Dinh, Bryan L., Tang, Echo, Taparra, Kekoa, Nakatsuka, Nathan, Chen, Fei, Chiang, Charleston W. K.
Publicado 2023

Evidence of widespread selection on standing variation in Europe at height-associated SNPs

por Turchin, Michael C., Chiang, Charleston W. K., Palmer, Cameron D., Sankararaman, Sriram, Reich, David, Hirschhorn, Joel N.
Publicado 2012

Tree-based QTL mapping with expected local genetic relatedness matrices

por Link, Vivian, Schraiber, Joshua G., Fan, Caoqi, Dinh, Bryan, Mancuso, Nicholas, Chiang, Charleston W.K., Edge, Michael D.
Publicado 2023

Inverted genomic regions between reference genome builds in humans impact imputation accuracy and decrease the power of association testing

por Sheng, Xin, Xia, Lucy, Cahoon, Jordan L., Conti, David V., Haiman, Christopher A., Kachuri, Linda, Chiang, Charleston W.K.
Publicado 2022

Imputation Accuracy Across Global Human Populations

por Cahoon, Jordan L., Rui, Xinyue, Tang, Echo, Simons, Christopher, Langie, Jalen, Chen, Minhui, Lo, Ying-Chu, Chiang, Charleston W. K.
Publicado 2023

Shared genetic basis informs the roles of polyunsaturated fatty acids in brain disorders

por Xu, Huifang, Sun, Yitang, Francis, Michael, Cheng, Claire F., Modulla, Nitya T.R., Brenna, J. Thomas, Chiang, Charleston W. K., Ye, Kaixiong
Publicado 2023

Evaluating Genomic Polygenic Risk Scores for Childhood Acute Lymphoblastic Leukemia in Latinos

por Jeon, Soyoung, Lo, Ying Chu, Morimoto, Libby M., Metayer, Catherine, Ma, Xiaomei, Wiemels, Joseph L., de Smith, Adam J., Chiang, Charleston W.K.
Publicado 2023

Evaluating genomic polygenic risk scores for childhood acute lymphoblastic leukemia in Latinos

por Jeon, Soyoung, Lo, Ying Chu, Morimoto, Libby M., Metayer, Catherine, Ma, Xiaomei, Wiemels, Joseph L., de Smith, Adam J., Chiang, Charleston W.K.
Publicado 2023

A likelihood-based framework for demographic inference from genealogical trees

por Fan, Caoqi, Cahoon, Jordan L., Dinh, Bryan L., Ortega-Del Vecchyo, Diego, Huber, Christian, Edge, Michael D., Mancuso, Nicholas, Chiang, Charleston W.K.
Publicado 2023

Localized variation in ancestral admixture identifies pilocytic astrocytoma risk loci among Latino children

por Li, Shaobo, Chiang, Charleston W. K., Myint, Swe Swe, Arroyo, Katti, Chan, Tsz Fung, Morimoto, Libby, Metayer, Catherine, de Smith, Adam J., Walsh, Kyle M., Wiemels, Joseph L.
Publicado 2022

Variant to function mapping at single-cell resolution through network propagation

por Yu, Fulong, Cato, Liam D., Weng, Chen, Liggett, L. Alexander, Jeon, Soyoung, Xu, Keren, Chiang, Charleston W.K., Wiemels, Joseph L., Weissman, Jonathan S., de Smith, Adam J., Sankaran, Vijay G.
Publicado 2022

Variant to function mapping at single-cell resolution through network propagation

por Yu, Fulong, Cato, Liam D., Weng, Chen, Liggett, L. Alexander, Jeon, Soyoung, Xu, Keren, Chiang, Charleston W. K., Wiemels, Joseph L., Weissman, Jonathan S., de Smith, Adam J., Sankaran, Vijay G.
Publicado 2022

Genomic history of the Sardinian population

por Chiang, Charleston W K, Marcus, Joseph H, Sidore, Carlo, Biddanda, Arjun, Al-Asadi, Hussein, Zoledziewska, Magdalena, Pitzalis, Maristella, Busonero, Fabio, Maschio, Andrea, Pistis, Giorgio, Steri, Maristella, Angius, Andrea, Lohmueller, Kirk E, Abecasis, Goncalo R, Schlessinger, David, Cucca, Francesco, Novembre, John
Publicado 2018

The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians

por Sun, Hanxiao, Lin, Meng, Russell, Emily M., Minster, Ryan L., Chan, Tsz Fung, Dinh, Bryan L., Naseri, Take, Reupena, Muagututi‘a Sefuiva, Lum-Jones, Annette, Cheng, Iona, Wilkens, Lynne R., Le Marchand, Loïc, Haiman, Christopher A., Chiang, Charleston W. K.
Publicado 2021

Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics

por Chan, Tsz Fung, Rui, Xinyue, Conti, David V., Fornage, Myriam, Graff, Mariaelisa, Haessler, Jeffrey, Haiman, Christopher, Highland, Heather M., Jung, Su Yon, Kenny, Eimear, Kooperberg, Charles, Marchland, Loic Le, North, Kari E., Tao, Ran, Wojcik, Genevieve, Gignoux, Christopher R., Chiang, Charleston W. K., Mancuso, Nicholas
Publicado 2023

Genomic analysis of the blood attributed to Louis XVI (1754–1793), king of France

por Olalde, Iñigo, Sánchez-Quinto, Federico, Datta, Debayan, Marigorta, Urko M., Chiang, Charleston W. K., Rodríguez, Juan Antonio, Fernández-Callejo, Marcos, González, Irene, Montfort, Magda, Matas-Lalueza, Laura, Civit, Sergi, Luiselli, Donata, Charlier, Philippe, Pettener, Davide, Ramírez, Oscar, Navarro, Arcadi, Himmelbauer, Heinz, Marquès-Bonet, Tomàs, Lalueza-Fox, Carles
Publicado 2014