A Novel Mouse Model Reveals that Polycystin-1 Deficiency in Ependyma and Choroid Plexus Results in Dysfunctional Cilia and Hydrocephalus

por Wodarczyk, Claas, Rowe, Isaline, Chiaravalli, Marco, Pema, Monika, Qian, Feng, Boletta, Alessandra
Publicado 2009

Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures

por Rowe, Isaline, Chiaravalli, Marco, Piontek, Klaus B., Germino, Gregory G., Boletta, Alessandra
Publicado 2014

Polycystin-1 Binds Par3/aPKC and Controls Convergent Extension During Renal Tubular Morphogenesis

por Castelli, Maddalena, Boca, Manila, Chiaravalli, Marco, Ramalingam, Harini, Rowe, Isaline, Distefano, Gianfranco, Carroll, Thomas, Boletta, Alessandra
Publicado 2013

Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness

por Nigro, Elisa Agnese, Distefano, Gianfranco, Chiaravalli, Marco, Matafora, Vittoria, Castelli, Maddalena, Pesenti Gritti, Angela, Bachi, Angela, Boletta, Alessandra
Publicado 2019

mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex

por Pema, Monika, Drusian, Luca, Chiaravalli, Marco, Castelli, Maddalena, Yao, Qin, Ricciardi, Sara, Somlo, Stefan, Qian, Feng, Biffo, Stefano, Boletta, Alessandra
Publicado 2016

Defective Glucose Metabolism in Polycystic Kidney Disease Identifies A Novel Therapeutic Paradigm

por Rowe, Isaline, Chiaravalli, Marco, Mannella, Valeria, Ulisse, Valeria, Quilici, Giacomo, Pema, Monika, Song, Xuewen W., Xu, Hangxue, Mari, Silvia, Qian, Feng, Pei, York, Musco, Giovanna, Boletta, Alessandra
Publicado 2013

Dissection of metabolic reprogramming in polycystic kidney disease reveals coordinated rewiring of bioenergetic pathways

por Podrini, Christine, Rowe, Isaline, Pagliarini, Roberto, Costa, Ana S. H., Chiaravalli, Marco, Di Meo, Ivano, Kim, Hyunho, Distefano, Gianfranco, Tiranti, Valeria, Qian, Feng, di Bernardo, Diego, Frezza, Christian, Boletta, Alessandra
Publicado 2018

Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism

por Kim, Hyunho, Xu, Hangxue, Yao, Qin, Li, Weizhe, Huang, Qiong, Outeda, Patricia, Cebotaru, Valeriu, Chiaravalli, Marco, Boletta, Alessandra, Piontek, Klaus, Germino, Gregory G., Weinman, Edward J., Watnick, Terry, Qian, Feng
Publicado 2014

Primary cilia sense glutamine availability and respond via asparagine synthetase

por Steidl, Maria Elena, Nigro, Elisa A., Nielsen, Anne Kallehauge, Pagliarini, Roberto, Cassina, Laura, Lampis, Matteo, Podrini, Christine, Chiaravalli, Marco, Mannella, Valeria, Distefano, Gianfranco, Yang, Ming, Aslanyan, Mariam, Musco, Giovanna, Roepman, Ronald, Frezza, Christian, Boletta, Alessandra
Publicado 2023

The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets

por Iaconis, Daniela, Monti, Maria, Renda, Mario, van Koppen, Arianne, Tammaro, Roberta, Chiaravalli, Marco, Cozzolino, Flora, Pignata, Paola, Crina, Claudia, Pucci, Piero, Boletta, Alessandra, Belcastro, Vincenzo, Giles, Rachel H., Surace, Enrico Maria, Gallo, Simone, Pende, Mario, Franco, Brunella
Publicado 2017