Epigenetic Control of a Local Chromatin Landscape

por Chiarella, Anna M., Lu, Dongbo, Hathaway, Nathaniel A.
Publicado 2020

Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery.

por Chiarella, Anna M., Butler, Kyle V., Gryder, Berkley E., Lu, Dongbo, Wang, Tiffany A., Yu, Xufen, Pomella, Silvia, Khan, Javed, Jin, Jian, Hathaway, Nathaniel A.
Publicado 2019

Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription

por Madigan, Victoria J., Yuziuk, Julianne A., Chiarella, Anna M., Tyson, Tyne O., Meganck, Rita M., Elmore, Zachary C., Tse, Longping V., Hathaway, Nathaniel A., Asokan, Aravind
Publicado 2019

Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma

por Gryder, Berkley E., Pomella, Silvia, Sayers, Carly, Wu, Xiaoli S., Song, Young, Chiarella, Anna M., Bagchi, Sukriti, Chou, Hsien-Chao, Sinniah, Ranu S., Walton, Ashley, Wen, Xinyu, Rota, Rossella, Hathaway, Nathaniel A., Zhao, Keji, Chen, Jiji, Vakoc, Christopher R., Shern, Jack F., Stanton, Benjamin Z., Khan, Javed
Publicado 2019

Mutant p53 regulates Survivin to foster lung metastasis

por Tang, Qiaosi, Efe, Gizem, Chiarella, Anna M., Leung, Jessica, Chen, Maoting, Yamazoe, Taiji, Su, Zhenyi, Pitarresi, Jason R., Li, Jinyang, Islam, Mirazul, Karakasheva, Tatiana, Klein-Szanto, Andres J., Pan, Samuel, Hu, Jianhua, Natsugoe, Shoji, Gu, Wei, Stanger, Ben Z., Wong, Kwok-K, Diehl, J. Alan, Bass, Adam J., Nakagawa, Hiroshi, Murphy, Maureen E., Rustgi, Anil K.
Publicado 2021

Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer

por Perez, Kimberly, Chiarella, Anna M, Cleary, James M, Horick, Nora, Weekes, Colin, Abrams, Thomas, Blaszkowsky, Lawrence, Enzinger, Peter, Giannakis, Marios, Goyal, Lipika, Meyerhardt, Jeffrey A, Rubinson, Douglas, Yurgelun, Matthew B, Goessling, Wolfram, Giantonio, Bruce J, Brais, Lauren, Germon, Victoria, Stonely, Danielle, Raghavan, Srivatsan, Bakir, Basil, Das, Koushik, Pitarresi, Jason R, Aguirre, Andrew J, Needle, Michael, Rustgi, Anil K, Wolpin, Brian M
Publicado 2023