Genetic Manipulation of NK Cells for Cancer Immunotherapy: Techniques and Clinical Implications

por Carlsten, Mattias, Childs, Richard W.
Publicado 2015

4th Edition of the International Autologous and Allogeneic Cell Therapy for Solid Tumors (ATST) Meeting

por Bregni, Marco, Childs, Richard W., Ueno, Naoto T.
Publicado 2011

Endogenous Retroviruses as Targets for Antitumor Immunity in Renal Cell Cancer and Other Tumors

por Cherkasova, Elena, Weisman, Quinn, Childs, Richard W.
Publicado 2013

Bortezomib Treatment to Potentiate the Anti-tumor Immunity of Ex-vivo Expanded Adoptively Infused Autologous Natural Killer Cells

por Lundqvist, Andreas, Berg, Maria, Smith, Aleah, Childs, Richard W.
Publicado 2011

1072. SARS-CoV-2 Antibody Levels Associate with Neutrophil Activation

por Warner, Seth, Miao, Rui, Ramos-Benitez, Marcos J, Tian, Xin, Reger, Robert, Burbelo, Peter D, Kanthi, Yogendra, Kanthi, Yogendra, Cohen, Jeffrey I, Suffredini, Anthony F, Nathan, Steven D, Childs, Richard W, Childs, Richard W, Childs, Richard W, Chertow, Daniel S, Strich, Jeffrey R
Publicado 2022

Improved Leukemia Clearance After Adoptive Transfer of NK Cells Expressing the Bone Marrow Homing Receptor CXCR4(R334X)

por Segerberg, Filip, Lambert, Mélanie, Sanz-Ortega, Laura, Andersson, Agneta, Childs, Richard W., Carlsten, Mattias
Publicado 2023

“Real-Time” High-Throughput Drug and Synergy Testing for Multidrug-Resistant Bacterial Infection: A Case Report

por Sun, Wei, Hesse, Shayla, Xu, Miao, Childs, Richard W., Zheng, Wei, Williamson, Peter R.
Publicado 2018

RNA-Seq Analysis Reveals CCR5 as a Key Target for CRISPR Gene Editing to Regulate In Vivo NK Cell Trafficking

por Levy, Emily R., Clara, Joseph A., Reger, Robert N., Allan, David S. J., Childs, Richard W.
Publicado 2021

Bortezomib sensitizes multiple myeloma to NK cells via ER-stress-induced suppression of HLA-E and upregulation of DR5

por Carlsten, Mattias, Namazi, Ali, Reger, Robert, Levy, Emily, Berg, Maria, St. Hilaire, Cynthia, Childs, Richard W.
Publicado 2018

Managing emerging transnational public health security threats: lessons learned from the 2014 West African Ebola outbreak

por Wendelboe, Aaron M., McCumber, Micah, Erb-Alvarez, Julie, Mould, Nicholas, Childs, Richard W., Regens, James L.
Publicado 2018

LIR‐1 educates expanded human NK cells and defines a unique antitumor NK cell subset with potent antibody‐dependent cellular cytotoxicity

por Leijonhufvud, Caroline, Reger, Robert, Segerberg, Filip, Theorell, Jakob, Schlums, Heinrich, Bryceson, Yenan T, Childs, Richard W, Carlsten, Mattias
Publicado 2021

Fully automated expansion and activation of clinical-grade natural killer cells for adoptive immunotherapy

por GRANZIN, MARKUS, SOLTENBORN, STEPHANIE, MÜLLER, SABINE, KOLLET, JUTTA, BERG, MARIA, CERWENKA, ADELHEID, CHILDS, RICHARD W., HUPPERT, VOLKER
Publicado 2015

Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-Induced ADCC against Lymphoma and Targets NK Cell Migration toward th...

por Carlsten, Mattias, Levy, Emily, Karambelkar, Amrita, Li, Linhong, Reger, Robert, Berg, Maria, Peshwa, Madhusudan V., Childs, Richard W.
Publicado 2016

Systematic improvements in lentiviral transduction of primary human natural killer cells undergoing ex vivo expansion

por Allan, David S.J., Chakraborty, Mala, Waller, Giacomo C., Hochman, Michael J., Poolcharoen, Akkapon, Reger, Robert N., Childs, Richard W.
Publicado 2021

Expanded NK cells used for adoptive cell therapy maintain diverse clonality and contain long-lived memory-like NK cell populations

por Allan, David S.J., Wu, Chuanfeng, Mortlock, Ryland D., Chakraborty, Mala, Rezvani, Katayoun, Davidson-Moncada, Jan K., Dunbar, Cynthia E., Childs, Richard W.
Publicado 2022

Fostamatinib Inhibits Neutrophils Extracellular Traps Induced by COVID-19 Patient Plasma: A Potential Therapeutic

por Strich, Jeffrey R, Ramos-Benitez, Marcos J, Randazzo, Davide, Stein, Sydney R, Babyak, Ashley, Davey, Richard T, Suffredini, Anthony F, Childs, Richard W, Chertow, Daniel S
Publicado 2020

Effect of high-dose plerixafor on CD34(+) cell mobilization in healthy stem cell donors: results of a randomized crossover trial

por Pantin, Jeremy, Purev, Enkhtsetseg, Tian, Xin, Cook, Lisa, Donohue-Jerussi, Theresa, Cho, Elena, Reger, Robert, Hsieh, Matthew, Khuu, Hanh, Calandra, Gary, Geller, Nancy L., Childs, Richard W.
Publicado 2017

Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones

por Smith, Richard H., Chen, Yun-Ching, Seifuddin, Fayaz, Hupalo, Daniel, Alba, Camille, Reger, Robert, Tian, Xin, Araki, Daisuke, Dalgard, Clifton L., Childs, Richard W., Pirooznia, Mehdi, Larochelle, Andre
Publicado 2020

Transcriptome analysis reveals similarities between human blood CD3(−) CD56(bright) cells and mouse CD127(+) innate lymphoid cells

por Allan, David S. J., Cerdeira, Ana Sofia, Ranjan, Anuisa, Kirkham, Christina L., Aguilar, Oscar A., Tanaka, Miho, Childs, Richard W., Dunbar, Cynthia E., Strominger, Jack L., Kopcow, Hernan D., Carlyle, James R.
Publicado 2017

Framingham Risk Score Is an Ineffective Screening Strategy for Coronary Heart Disease in Long-Term Allogeneic Hematopoietic Cell Transplant Survivors

por Jain, Natasha A., Chen, Marcus Y., Shanbhag, Sujata, Anandi, Prathima, Tian, Xin, Ito, Sawa, Pophali, Priyanka A., Doucette, Kimberly, Le, Robert Q., Chawla, Upneet, Koklanaris, Eleftheria, Childs, Richard W., Barrett, A. John, Battiwalla, Minoo
Publicado 2020