Genome-wide transcriptomics identifies an early preclinical signature of prion infection

por Sorce, Silvia, Nuvolone, Mario, Russo, Giancarlo, Chincisan, Andra, Heinzer, Daniel, Avar, Merve, Pfammatter, Manuela, Schwarz, Petra, Delic, Mirzet, Müller, Micha, Hornemann, Simone, Sanoudou, Despina, Scheckel, Claudia, Aguzzi, Adriano
Publicado 2020

Prion pathogenesis is unaltered in a mouse strain with a permeable blood-brain barrier

por Keller, Annika, Nuvolone, Mario, Abakumova, Irina, Chincisan, Andra, Reimann, Regina, Avar, Merve, Heinzer, Daniel, Hornemann, Simone, Wagner, Josephin, Kirschenbaum, Daniel, Voigt, Fabian F., Zhu, Caihong, Regli, Luca, Helmchen, Fritjof, Aguzzi, Adriano
Publicado 2018

Novel regulators of PrP(C) biosynthesis revealed by genome-wide RNA interference

por Heinzer, Daniel, Avar, Merve, Pease, Daniel Patrick, Dhingra, Ashutosh, Yin, Jiang-An, Schaper, Elke, Doğançay, Berre, Emmenegger, Marc, Spinelli, Anna, Maggi, Kevin, Chincisan, Andra, Mead, Simon, Hornemann, Simone, Heutink, Peter, Aguzzi, Adriano
Publicado 2021

Protective anti‐prion antibodies in human immunoglobulin repertoires

por Senatore, Assunta, Frontzek, Karl, Emmenegger, Marc, Chincisan, Andra, Losa, Marco, Reimann, Regina, Horny, Geraldine, Guo, Jingjing, Fels, Sylvie, Sorce, Silvia, Zhu, Caihong, George, Nathalie, Ewert, Stefan, Pietzonka, Thomas, Hornemann, Simone, Aguzzi, Adriano
Publicado 2020

An arrayed genome‐wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate‐limiting for prion propagation

por Avar, Merve, Heinzer, Daniel, Thackray, Alana M, Liu, Yingjun, Hruska‐Plochan, Marian, Sellitto, Stefano, Schaper, Elke, Pease, Daniel P, Yin, Jiang‐An, Lakkaraju, Asvin KK, Emmenegger, Marc, Losa, Marco, Chincisan, Andra, Hornemann, Simone, Polymenidou, Magdalini, Bujdoso, Raymond, Aguzzi, Adriano
Publicado 2022

An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein

por Kara, Eleanna, Crimi, Alessandro, Wiedmer, Anne, Emmenegger, Marc, Manzoni, Claudia, Bandres-Ciga, Sara, D’Sa, Karishma, Reynolds, Regina H., Botía, Juan A., Losa, Marco, Lysenko, Veronika, Carta, Manfredi, Heinzer, Daniel, Avar, Merve, Chincisan, Andra, Blauwendraat, Cornelis, García-Ruiz, Sonia, Pease, Daniel, Mottier, Lorene, Carrella, Alessandra, Beck-Schneider, Dezirae, Magalhães, Andreia D., Aemisegger, Caroline, Theocharides, Alexandre P.A., Fan, Zhanyun, Marks, Jordan D., Hopp, Sarah C., Abramov, Andrey Y., Lewis, Patrick A., Ryten, Mina, Hardy, John, Hyman, Bradley T., Aguzzi, Adriano
Publicado 2021