Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

por Luo, Wenjie, Rodina, Anna, Chiosis, Gabriela
Publicado 2008

The epichaperome: the power of many as the power of one

por Tai, Wang, Guzman, Monica L., Chiosis, Gabriela
Publicado 2016

Heat shock protein 90 in neurodegenerative diseases

por Luo, Wenjie, Sun, Weilin, Taldone, Tony, Rodina, Anna, Chiosis, Gabriela
Publicado 2010

The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1

por Usmani, Saad Z, Bona, Robert D, Chiosis, Gabriela, Li, Zihai
Publicado 2010

Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention

por Carman, Aaron, Kishinevsky, Sarah, Koren, John, Lou, Wenjie, Chiosis, Gabriela
Publicado 2013

Physical plasma-triggered ROS induces tumor cell death upon cleavage of HSP90 chaperone

por Bekeschus, Sander, Lippert, Maxi, Diepold, Kristina, Chiosis, Gabriela, Seufferlein, Thomas, Azoitei, Ninel
Publicado 2019

Selective inhibition of hsp90 paralogs: Structure and binding studies uncover the role of helix 1 in Grp94-selective ligand binding

por Que, Nanette L. S., Seidler, Paul M., Aw, Wen J., Chiosis, Gabriela, Gewirth, Daniel T.
Publicado 2023

A Purine Analog Synergizes with Chloroquine (CQ) by Targeting Plasmodium falciparum Hsp90 (PfHsp90)

por Shahinas, Dea, Folefoc, Asongna, Taldone, Tony, Chiosis, Gabriela, Crandall, Ian, Pillai, Dylan R.
Publicado 2013

Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol‐Associated Liver Disease

por Ratna, Anuradha, Lim, Arlene, Li, Zihai, Argemi, Josepmaria, Bataller, Ramon, Chiosis, Gabriela, Mandrekar, Pranoti
Publicado 2021

Hsp90 is a viable therapeutic target in the treatment of KSHV-associated primary effusion lymphoma

por Nayar, Utthara, Lu, Pin, Vider, Jelena, Cerchietti, Leandro, Chiosis, Gabriela, Wang, Lynn, Blasberg, Ronald, Cesarman, Ethel
Publicado 2010

Radioiodinated PARP1 tracers for glioblastoma imaging

por Salinas, Beatriz, Irwin, Christopher P., Kossatz, Susanne, Bolaender, Alexander, Chiosis, Gabriela, Pillarsetty, Nagavarakishore, Weber, Wolfgang A., Reiner, Thomas
Publicado 2015

STK33 participates to HSP90-supported angiogenic program in hypoxic tumors by regulating HIF-1α/VEGF signaling pathway

por Liu, Yang, Steinestel, Konrad, Rouhi, Arefeh, Armacki, Milena, Diepold, Kristina, Chiosis, Gabriela, Simmet, Thomas, Seufferlein, Thomas, Azoitei, Ninel
Publicado 2017

Unraveling the Mechanism of Epichaperome Modulation by Zelavespib: Biochemical Insights on Target Occupancy and Extended Residence Time at the Site of Action

por Sharma, Sahil, Joshi, Suhasini, Kalidindi, Teja, Digwal, Chander S., Panchal, Palak, Lee, Sang-Gyu, Zanzonico, Pat, Pillarsetty, Nagavarakishore, Chiosis, Gabriela
Publicado 2023

Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using (89)Zr-DFO-Trastuzumab

por Holland, Jason P., Caldas-Lopes, Eloisi, Divilov, Vadim, Longo, Valerie A., Taldone, Tony, Zatorska, Danuta, Chiosis, Gabriela, Lewis, Jason S.
Publicado 2010

Assay Strategies for the Discovery and Validation of Therapeutics Targeting Brugia pahangi Hsp90

por Taldone, Tony, Gillan, Victoria, Sun, Weilin, Rodina, Anna, Patel, Pallav, Maitland, Kirsty, O'Neill, Kerry, Chiosis, Gabriela, Devaney, Eileen
Publicado 2010

Synthesis of (124)I-labeled epichaperome probes and assessment in visualizing pathologic protein-protein interaction networks in tumor bearing mice

por Sharma, Sahil, Kalidindi, Teja, Joshi, Suhasini, Digwal, Chander S., Panchal, Palak, Burnazi, Eva, Lee, Sang Gyu, Pillarsetty, Nagavarakishore, Chiosis, Gabriela
Publicado 2022

Environment-responsive Nanophores for Therapy and Treatment Monitoring via Molecular MRI Quenching

por Kaittanis, Charalambos, Shaffer, Travis M., Ogirala, Anuja, Santra, Santimukul, Perez, J. Manuel, Chiosis, Gabriela, Li, Yueming, Josephson, Lee, Grimm, Jan
Publicado 2014

Author Correction: Environment-responsive nanophores for therapy and treatment monitoring via molecular MRI quenching

por Kaittanis, Charalambos, Shaffer, Travis M., Ogirala, Anuja, Santra, Santimukul, Perez, J. Manuel, Chiosis, Gabriela, Li, Yueming, Josephson, Lee, Grimm, Jan
Publicado 2019

Synthesis and evaluation of cell-permeable biotinylated PU-H71 derivatives as tumor Hsp90 probes

por Taldone, Tony, Rodina, Anna, DaGama Gomes, Erica M, Riolo, Matthew, Patel, Hardik J, Alonso-Sabadell, Raul, Zatorska, Danuta, Patel, Maulik R, Kishinevsky, Sarah, Chiosis, Gabriela
Publicado 2013

Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

por Kang, Yanlong, Taldone, Tony, Patel, Hardik J., Patel, Pallav D., Rodina, Anna, Gozman, Alexander, Maharaj, Ronnie, Clement, Cristina C., Patel, Maulik R., Brodsky, Jeffrey L., Young, Jason C., Chiosis, Gabriela
Publicado 2014