Protein chainmail variants in dsDNA viruses

por Zhou, Z. Hong, Chiou, Joshua
Publicado 2015

Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes

por Aylward, Anthony, Okino, Mei-Lin, Benaglio, Paola, Chiou, Joshua, Beebe, Elisha, Padilla, Jose Andres, Diep, Sharlene, Gaulton, Kyle J.
Publicado 2021

Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral blood

por Benaglio, Paola, Newsome, Jacklyn, Han, Jee Yun, Chiou, Joshua, Aylward, Anthony, Corban, Sierra, Miller, Michael, Okino, Mei-Lin, Kaur, Jaspreet, Preissl, Sebastian, Gorkin, David U., Gaulton, Kyle J.
Publicado 2023

Common DNA sequence variation influences 3-dimensional conformation of the human genome

por Gorkin, David U., Qiu, Yunjiang, Hu, Ming, Fletez-Brant, Kipper, Liu, Tristin, Schmitt, Anthony D., Noor, Amina, Chiou, Joshua, Gaulton, Kyle J., Sebat, Jonathan, Li, Yun, Hansen, Kasper D., Ren, Bing
Publicado 2019

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development

por Geusz, Ryan J, Wang, Allen, Chiou, Joshua, Lancman, Joseph J, Wetton, Nichole, Kefalopoulou, Samy, Wang, Jinzhao, Qiu, Yunjiang, Yan, Jian, Aylward, Anthony, Ren, Bing, Dong, P Duc Si, Gaulton, Kyle J, Sander, Maike
Publicado 2021

Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis

por Udler, Miriam S., Kim, Jaegil, von Grotthuss, Marcin, Bonàs-Guarch, Sílvia, Cole, Joanne B., Chiou, Joshua, Boehnke, Michael, Laakso, Markku, Atzmon, Gil, Glaser, Benjamin, Mercader, Josep M., Gaulton, Kyle, Flannick, Jason, Getz, Gad, Florez, Jose C.
Publicado 2018

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors

por Geusz, Ryan J., Wang, Allen, Lam, Dieter K., Vinckier, Nicholas K., Alysandratos, Konstantinos-Dionysios, Roberts, David A., Wang, Jinzhao, Kefalopoulou, Samy, Ramirez, Araceli, Qiu, Yunjiang, Chiou, Joshua, Gaulton, Kyle J., Ren, Bing, Kotton, Darrell N., Sander, Maike
Publicado 2021

The long noncoding RNA ROCKI regulates inflammatory gene expression

por Zhang, Qiong, Chao, Ti‐Chun, Patil, Veena S, Qin, Yue, Tiwari, Shashi Kant, Chiou, Joshua, Dobin, Alexander, Tsai, Chih‐Ming, Li, Zhonghan, Dang, Jason, Gupta, Shagun, Urdahl, Kevin, Nizet, Victor, Gingeras, Thomas R, Gaulton, Kyle J, Rana, Tariq M
Publicado 2019

A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells

por Jin, Wen, Mulas, Francesca, Gaertner, Bjoern, Sui, Yinghui, Wang, Jinzhao, Matta, Ileana, Zeng, Chun, Vinckier, Nicholas, Wang, Allen, Nguyen-Ngoc, Kim-Vy, Chiou, Joshua, Kaestner, Klaus H., Frazer, Kelly A., Carrano, Andrea C., Shih, Hung-Ping, Sander, Maike
Publicado 2019

Cardiac cell type–specific gene regulatory programs and disease risk association

por Hocker, James D., Poirion, Olivier B., Zhu, Fugui, Buchanan, Justin, Zhang, Kai, Chiou, Joshua, Wang, Tsui-Min, Zhang, Qingquan, Hou, Xiaomeng, Li, Yang E., Zhang, Yanxiao, Farah, Elie N., Wang, Allen, McCulloch, Andrew D., Gaulton, Kyle J., Ren, Bing, Chi, Neil C., Preissl, Sebastian
Publicado 2021

Single cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk

por Chiou, Joshua, Zeng, Chun, Cheng, Zhang, Han, Jee Yun, Schlichting, Michael, Miller, Michael, Mendez, Robert, Huang, Serina, Wang, Jinzhao, Sui, Yinghui, Deogaygay, Allison, Okino, Mei-Lin, Qiu, Yunjiang, Sun, Ying, Kudtarkar, Parul, Fang, Rongxin, Preissl, Sebastian, Sander, Maike, Gorkin, David U, Gaulton, Kyle J
Publicado 2021

Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk

por Greenwald, William W., Chiou, Joshua, Yan, Jian, Qiu, Yunjiang, Dai, Ning, Wang, Allen, Nariai, Naoki, Aylward, Anthony, Han, Jee Yun, Kadakia, Nikita, Regue, Laura, Okino, Mei-Lin, Drees, Frauke, Kramer, Dana, Vinckier, Nicholas, Minichiello, Liliana, Gorkin, David, Avruch, Joseph, Frazer, Kelly A., Sander, Maike, Ren, Bing, Gaulton, Kyle J.
Publicado 2019

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines

por Benaglio, Paola, Zhu, Han, Okino, Mei-Lin, Yan, Jian, Elgamal, Ruth, Nariai, Naoki, Beebe, Elisha, Korgaonkar, Katha, Qiu, Yunjiang, Donovan, Margaret K.R., Chiou, Joshua, Wang, Gaowei, Newsome, Jacklyn, Kaur, Jaspreet, Miller, Michael, Preissl, Sebastian, Corban, Sierra, Aylward, Anthony, Taipale, Jussi, Ren, Bing, Frazer, Kelly A., Sander, Maike, Gaulton, Kyle J.
Publicado 2022

Nutrient regulation of the islet epigenome controls adaptive insulin secretion

por Wortham, Matthew, Liu, Fenfen, Harrington, Austin R., Fleischman, Johanna Y., Wallace, Martina, Mulas, Francesca, Mallick, Medhavi, Vinckier, Nicholas K., Cross, Benjamin R., Chiou, Joshua, Patel, Nisha A., Sui, Yinghui, McGrail, Carolyn, Jun, Yesl, Wang, Gaowei, Jhala, Ulupi S., Schüle, Roland, Shirihai, Orian S., Huising, Mark O., Gaulton, Kyle J., Metallo, Christian M., Sander, Maike
Publicado 2023

Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes

por Wang, Gaowei, Chiou, Joshua, Zeng, Chun, Miller, Michael, Matta, Ileana, Han, Jee Yun, Kadakia, Nikita, Okino, Mei-Lin, Beebe, Elisha, Mallick, Medhavi, Camunas-Soler, Joan, dos Santos, Theodore, Dai, Xiao-Qing, Ellis, Cara, Hang, Yan, Kim, Seung K., MacDonald, Patrick E., Kandeel, Fouad R., Preissl, Sebastian, Gaulton, Kyle J, Sander, Maike
Publicado 2023

Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes

por Wang, Allen, Chiou, Joshua, Poirion, Olivier B, Buchanan, Justin, Valdez, Michael J, Verheyden, Jamie M, Hou, Xiaomeng, Kudtarkar, Parul, Narendra, Sharvari, Newsome, Jacklyn M, Guo, Minzhe, Faddah, Dina A, Zhang, Kai, Young, Randee E, Barr, Justinn, Sajti, Eniko, Misra, Ravi, Huyck, Heidie, Rogers, Lisa, Poole, Cory, Whitsett, Jeffery A, Pryhuber, Gloria, Xu, Yan, Gaulton, Kyle J, Preissl, Sebastian, Sun, Xin
Publicado 2020

An atlas of gene regulatory elements in adult mouse cerebrum

por Li, Yang Eric, Preissl, Sebastian, Hou, Xiaomeng, Zhang, Ziyang, Zhang, Kai, Qiu, Yunjiang, Poirion, Olivier B., Li, Bin, Chiou, Joshua, Liu, Hanqing, Pinto-Duarte, Antonio, Kubo, Naoki, Yang, Xiaoyu, Fang, Rongxin, Wang, Xinxin, Han, Jee Yun, Lucero, Jacinta, Yan, Yiming, Miller, Michael, Kuan, Samantha, Gorkin, David, Gaulton, Kyle J., Shen, Yin, Nunn, Michael, Mukamel, Eran A., Behrens, M. Margarita, Ecker, Joseph R., Ren, Bing
Publicado 2021

An atlas of dynamic chromatin landscapes in mouse fetal development

por Gorkin, David U., Barozzi, Iros, Zhao, Yuan, Zhang, Yanxiao, Huang, Hui, Lee, Ah Young, Li, Bin, Chiou, Joshua, Wildberg, Andre, Ding, Bo, Zhang, Bo, Wang, Mengchi, Strattan, J. Seth, Davidson, Jean M., Qiu, Yunjiang, Afzal, Veena, Akiyama, Jennifer A., Plajzer-Frick, Ingrid, Novak, Catherine S., Kato, Momoe, Garvin, Tyler H., Pham, Quan T., Harrington, Anne N., Mannion, Brandon J., Lee, Elizabeth A., Fukuda-Yuzawa, Yoko, He, Yupeng, Preissl, Sebastian, Chee, Sora, Han, Jee Yun, Williams, Brian A., Trout, Diane, Amrhein, Henry, Yang, Hongbo, Cherry, J. Michael, Wang, Wei, Gaulton, Kyle, Ecker, Joseph R., Shen, Yin, Dickel, Diane E., Visel, Axel, Pennacchio, Len A., Ren, Bing
Publicado 2020

Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development

por Gorkin, David U., Barozzi, Iros, Zhao, Yuan, Zhang, Yanxiao, Huang, Hui, Lee, Ah Young, Li, Bin, Chiou, Joshua, Wildberg, Andre, Ding, Bo, Zhang, Bo, Wang, Mengchi, Strattan, J. Seth, Davidson, Jean M., Qiu, Yunjiang, Afzal, Veena, Akiyama, Jennifer A., Plajzer-Frick, Ingrid, Novak, Catherine S., Kato, Momoe, Garvin, Tyler H., Pham, Quan T., Harrington, Anne N., Mannion, Brandon J., Lee, Elizabeth A., Fukuda-Yuzawa, Yoko, He, Yupeng, Preissl, Sebastian, Chee, Sora, Han, Jee Yun, Williams, Brian A., Trout, Diane, Amrhein, Henry, Yang, Hongbo, Cherry, J. Michael, Wang, Wei, Gaulton, Kyle, Ecker, Joseph R., Shen, Yin, Dickel, Diane E., Visel, Axel, Pennacchio, Len A., Ren, Bing
Publicado 2020

Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development

por Gorkin, David U., Barozzi, Iros, Zhao, Yuan, Zhang, Yanxiao, Huang, Hui, Lee, Ah Young, Li, Bin, Chiou, Joshua, Wildberg, Andre, Ding, Bo, Zhang, Bo, Wang, Mengchi, Strattan, J. Seth, Davidson, Jean M., Qiu, Yunjiang, Afzal, Veena, Akiyama, Jennifer A., Plajzer-Frick, Ingrid, Novak, Catherine S., Kato, Momoe, Garvin, Tyler H., Pham, Quan T., Harrington, Anne N., Mannion, Brandon J., Lee, Elizabeth A., Fukuda-Yuzawa, Yoko, He, Yupeng, Preissl, Sebastian, Chee, Sora, Han, Jee Yun, Williams, Brian A., Trout, Diane, Amrhein, Henry, Yang, Hongbo, Cherry, J. Michael, Wang, Wei, Gaulton, Kyle, Ecker, Joseph R., Shen, Yin, Dickel, Diane E., Visel, Axel, Pennacchio, Len A., Ren, Bing
Publicado 2021