Crystal Structure of DNA-PKcs Reveals a Large Open-Ring Cradle Comprised of HEAT Repeats

por Sibanda, Bancinyane L., Chirgadze, Dimitri Y., Blundell, Tom L.
Publicado 2009

A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly

por Appleby, Robert, Bollschweiler, Daniel, Chirgadze, Dimitri Y., Joudeh, Luay, Pellegrini, Luca
Publicado 2023

Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors

por Blaszczyk, Michal, Harmer, Nicholas J., Chirgadze, Dimitri Y., Ascher, David B., Blundell, Tom L.
Publicado 2015

CryoEM structures of human CMG–ATPγS–DNA and CMG–AND-1 complexes

por Rzechorzek, Neil J, Hardwick, Steven W, Jatikusumo, Vincentius A, Chirgadze, Dimitri Y, Pellegrini, Luca
Publicado 2020

OXA-66 structure and oligomerisation of OXAAb enzymes

por Takebayashi, Yuiko, Henderson, Sara R., Chirgadze, Dimitri Y., Warburton, Philip J., Evans, Benjamin A.
Publicado 2022

5-Formylcytosine alters the structure of the DNA double helix

por Raiber, Eun-Ang, Murat, Pierre, Chirgadze, Dimitri Y., Beraldi, Dario, Luisi, Ben F., Balasubramanian, Shankar
Publicado 2014

Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining

por Ochi, Takashi, Sibanda, Bancinyane Lynn, Wu, Qian, Chirgadze, Dimitri Y., Bolanos-Garcia, Victor M., Blundell, Tom L.
Publicado 2010

Structural Insights into the Role of Domain Flexibility in Human DNA Ligase IV

por Ochi, Takashi, Wu, Qian, Chirgadze, Dimitri Y., Grossmann, J. Günter, Bolanos-Garcia, Victor M., Blundell, Tom L.
Publicado 2012

A new look at sodium channel β subunits

por Namadurai, Sivakumar, Yereddi, Nikitha R., Cusdin, Fiona S., Huang, Christopher L.-H., Chirgadze, Dimitri Y., Jackson, Antony P.
Publicado 2015

Zn(II) mediates vancomycin polymerization and potentiates its antibiotic activity against resistant bacteria

por Zarkan, Ashraf, Macklyne, Heather-Rose, Chirgadze, Dimitri Y., Bond, Andrew D., Hesketh, Andrew R., Hong, Hee-Jeon
Publicado 2017

Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs

por Liang, Shikang, Thomas, Sherine E., Chaplin, Amanda K., Hardwick, Steven W., Chirgadze, Dimitri Y., Blundell, Tom L.
Publicado 2022

Amyloid-like Fibrils from an α-Helical Transmembrane Protein

por Stroobants, Karen, Kumita, Janet R., Harris, Nicola J., Chirgadze, Dimitri Y., Dobson, Christopher M., Booth, Paula J., Vendruscolo, Michele
Publicado 2017

Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis

por Islam, Md Saiful, Hardwick, Steven W, Quell, Laura, Durica‐Mitic, Svetlana, Chirgadze, Dimitri Y, Görke, Boris, Luisi, Ben F
Publicado 2022

Using cryo-EM to understand antimycobacterial resistance in the catalase-peroxidase (KatG) from Mycobacterium tuberculosis

por Munir, Asma, Wilson, Michael T., Hardwick, Steven W., Chirgadze, Dimitri Y., Worrall, Jonathan A.R., Blundell, Tom L., Chaplin, Amanda K.
Publicado 2021

Crystal Structure and Molecular Imaging of the Na(v) Channel β3 Subunit Indicates a Trimeric Assembly

por Namadurai, Sivakumar, Balasuriya, Dilshan, Rajappa, Rajit, Wiemhöfer, Martin, Stott, Katherine, Klingauf, Jurgen, Edwardson, J. Michael, Chirgadze, Dimitri Y., Jackson, Antony P.
Publicado 2014

Mechanisms of inhibition and activation of extrasynaptic αβ GABA(A) receptors

por Kasaragod, Vikram Babu, Mortensen, Martin, Hardwick, Steven W., Wahid, Ayla A., Dorovykh, Valentina, Chirgadze, Dimitri Y., Smart, Trevor G., Miller, Paul S.
Publicado 2022

Publisher Correction: Mechanisms of inhibition and activation of extrasynaptic αβ GABA(A) receptors

por Kasaragod, Vikram Babu, Mortensen, Martin, Hardwick, Steven W., Wahid, Ayla A., Dorovykh, Valentina, Chirgadze, Dimitri Y., Smart, Trevor G., Miller, Paul S.
Publicado 2022

Structural basis for the interaction of SARS‐CoV‐2 virulence factor nsp1 with DNA polymerase α–primase

por Kilkenny, Mairi L., Veale, Charlotte E., Guppy, Amir, Hardwick, Steven W., Chirgadze, Dimitri Y., Rzechorzek, Neil J., Maman, Joseph D., Pellegrini, Luca
Publicado 2021

Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ

por Li, Yi, Chirgadze, Dimitri Y, Bolanos-Garcia, Victor M, Sibanda, Bancinyane L, Davies, Owen R, Ahnesorg, Peter, Jackson, Stephen P, Blundell, Tom L
Publicado 2008

Structure of a Single-Chain Fv Bound to the 17 N-Terminal Residues of Huntingtin Provides Insights into Pathogenic Amyloid Formation and Suppression

por De Genst, Erwin, Chirgadze, Dimitri Y., Klein, Fabrice A.C., Butler, David C., Matak-Vinković, Dijana, Trottier, Yvon, Huston, James S., Messer, Anne, Dobson, Christopher M.
Publicado 2015