P546: MACHINE LEARNING AND RESPONSE TO INDUCTION CHEMOTHERAPY IN PATIENTS WITH ACUTE MYELOID LEUKEMIA

por Elhaddad, Heba, Chiriches, Claudia, Watts, Katie, Giles, Peter, Gilkes, Amanda, Ruthardt, Martin
Publicado 2023

P456: LEUKEMOGENESIS BY AML-SPECIFIC DRIVER MUTATIONS WITHIN DNMT3A, IDH2 AND NPM1

por Mehmetbeyoglu, Ecmel, Chiriches, Claudia, Shair Mohammed, Imran, Nur Onat, Beyza, Yaray, Kadir, Galip Yildiz, Oguz, Taheri, Serpil, Ruthardt, Martin
Publicado 2023

Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation

por Chiriches, Claudia, Nicolaisen, Nathalie, Wieske, Maria, Elhaddad, Heba, Mehmetbeyoglu, Ecmel, Alvares, Caroline, Becher, Dörte, Hole, Paul, Ottmann, Oliver Gerhard, Ruthardt, Martin
Publicado 2022

Activation of signaling pathways in models of t(6;9)-acute myeloid leukemia

por Chiriches, Claudia, Khan, Dilawar, Wieske, Maria, Guillen, Nathalie, Rokicki, Michal, Guy, Carol, Wilson, Marieangela, Heesom, Kate J., Ottmann, Oliver Gerhard, Ruthardt, Martin
Publicado 2022

Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1(T315I) and...

por Mian, Afsar Ali, Haberbosch, Isabella, Khamaisie, Hazem, Agbarya, Abed, Pietsch, Larissa, Eshel, Elizabeh, Najib, Dally, Chiriches, Claudia, Ottmann, Oliver Gerhard, Hantschel, Oliver, Biondi, Ricardo M., Ruthardt, Martin, Mahajna, Jamal
Publicado 2021