CpG methylation potentiates pixantrone and doxorubicin-induced DNA damage and is a marker of drug sensitivity

por Evison, Benny J., Bilardi, Rebecca A., Chiu, Francis C. K., Pezzoni, Gabriella, Phillips, Don R., Cutts, Suzanne M.
Publicado 2009

Using Human Plasma as an Assay Medium in Caco-2 Studies Improves Mass Balance for Lipophilic Compounds

por Katneni, Kasiram, Pham, Thao, Saunders, Jessica, Chen, Gong, Patil, Rahul, White, Karen L., Abla, Nada, Chiu, Francis C. K., Shackleford, David M., Charman, Susan A.
Publicado 2018

Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins

por Xie, Stanley C., Dogovski, Con, Hanssen, Eric, Chiu, Francis, Yang, Tuo, Crespo, Maria P., Stafford, Che, Batinovic, Steven, Teguh, Silvia, Charman, Susan, Klonis, Nectarios, Tilley, Leann
Publicado 2016

Revisiting the SAR of the Antischistosomal Aryl Hydantoin (Ro 13-3978)

por Wang, Chunkai, Zhao, Qingjie, Vargas, Mireille, Jones, Jeremy O., White, Karen L., Shackleford, David M., Chen, Gong, Saunders, Jessica, Ng, Alice C. F., Chiu, Francis C. K., Dong, Yuxiang, Charman, Susan A., Keiser, Jennifer, Vennerstrom, Jonathan L.
Publicado 2016

Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12)

por Dong, Yuxiang, Sonawane, Yogesh, Maher, Steven P., Zeeman, Anne-Marie, Chaumeau, Victor, Vantaux, Amélie, Cooper, Caitlin A., Chiu, Francis C. K., Ryan, Eileen, McLaren, Jenna, Chen, Gong, Wittlin, Sergio, Witkowski, Benoît, Nosten, François, Sriraghavan, Kamaraj, Kyle, Dennis E., Kocken, Clemens H. M., Charman, Susan A., Vennerstrom, Jonathan L.
Publicado 2022

Two Analogues of Fenarimol Show Curative Activity in an Experimental Model of Chagas Disease

por Keenan, Martine, Chaplin, Jason H., Alexander, Paul W., Abbott, Michael J., Best, Wayne M., Khong, Andrea, Botero, Adriana, Perez, Catherine, Cornwall, Scott, Thompson, R. Andrew, White, Karen L., Shackleford, David M., Koltun, Maria, Chiu, Francis C. K., Morizzi, Julia, Ryan, Eileen, Campbell, Michael, von Geldern, Thomas W., Scandale, Ivan, Chatelain, Eric, Charman, Susan A.
Publicado 2013

An in vitro toolbox to accelerate anti-malarial drug discovery and development

por Charman, Susan A., Andreu, Alice, Barker, Helena, Blundell, Scott, Campbell, Anna, Campbell, Michael, Chen, Gong, Chiu, Francis C. K., Crighton, Elly, Katneni, Kasiram, Morizzi, Julia, Patil, Rahul, Pham, Thao, Ryan, Eileen, Saunders, Jessica, Shackleford, David M., White, Karen L., Almond, Lisa, Dickins, Maurice, Smith, Dennis A., Moehrle, Joerg J., Burrows, Jeremy N., Abla, Nada
Publicado 2020

The hypoxia imaging agent Cu(II)(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson’s disease

por Hung, Lin W., Villemagne, Victor L., Cheng, Lesley, Sherratt, Nicki A., Ayton, Scott, White, Anthony R., Crouch, Peter J., Lim, SinChun, Leong, Su Ling, Wilkins, Simon, George, Jessica, Roberts, Blaine R., Pham, Chi L.L., Liu, Xiang, Chiu, Francis C.K., Shackleford, David M., Powell, Andrew K., Masters, Colin L., Bush, Ashley I., O’Keefe, Graeme, Culvenor, Janetta G., Cappai, Roberto, Cherny, Robert A., Donnelly, Paul S., Hill, Andrew F., Finkelstein, David I., Barnham, Kevin J.
Publicado 2012