Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer

por Gong, Fade, Chiu, Li-Ya, Miller, Kyle M.
Publicado 2016

Selective ATM inhibition augments radiation-induced inflammatory signaling and cancer cell death

por Chiu, Li-Ya, Sun, Qing, Zenke, Frank T., Blaukat, Andree, Vassilev, Lyubomir T.
Publicado 2023

DNA-PK Inhibitor, M3814, as a New Combination Partner of Mylotarg in the Treatment of Acute Myeloid Leukemia

por Carr, Michael I., Zimmermann, Astrid, Chiu, Li-Ya, Zenke, Frank T., Blaukat, Andree, Vassilev, Lyubomir T.
Publicado 2020

Selective Inhibition of ATM-dependent Double-strand Break Repair and Checkpoint Control Synergistically Enhances the Efficacy of ATR Inhibitors

por Turchick, Audrey, Zimmermann, Astrid, Chiu, Li-Ya, Dahmen, Heike, Elenbaas, Brian, Zenke, Frank T., Blaukat, Andree, Vassilev, Lyubomir T.
Publicado 2023

A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies

por Zimmermann, Astrid, Zenke, Frank T., Chiu, Li-Ya, Dahmen, Heike, Pehl, Ulrich, Fuchss, Thomas, Grombacher, Thomas, Blume, Beatrix, Vassilev, Lyubomir T., Blaukat, Andree
Publicado 2022

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination

por Gong, Fade, Chiu, Li-Ya, Cox, Ben, Aymard, François, Clouaire, Thomas, Leung, Justin W., Cammarata, Michael, Perez, Mercedes, Agarwal, Poonam, Brodbelt, Jennifer S., Legube, Gaëlle, Miller, Kyle M.
Publicado 2015

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair

por Leung, Justin W.C., Makharashvili, Nodar, Agarwal, Poonam, Chiu, Li-Ya, Pourpre, Renaud, Cammarata, Michael B., Cannon, Joe R., Sherker, Alana, Durocher, Daniel, Brodbelt, Jennifer S., Paull, Tanya T., Miller, Kyle M.
Publicado 2017

DNA-PK Inhibitor Peposertib Amplifies Radiation-Induced Inflammatory Micronucleation and Enhances TGFβ/PD-L1 Targeted Cancer Immunotherapy

por Carr, Michael I., Chiu, Li-Ya, Guo, Yige, Xu, Chunxiao, Lazorchak, Adam S., Yu, Huakui, Qin, Guozhong, Qi, Jin, Marelli, Bo, Lan, Yan, Sun, Qing, Czauderna, Frank, Zenke, Frank T., Blaukat, Andree, Vassilev, Lyubomir T.
Publicado 2022

Engineered proteins detect spontaneous DNA breakage in human and bacterial cells

por Shee, Chandan, Cox, Ben D, Gu, Franklin, Luengas, Elizabeth M, Joshi, Mohan C, Chiu, Li-Ya, Magnan, David, Halliday, Jennifer A, Frisch, Ryan L, Gibson, Janet L, Nehring, Ralf Bernd, Do, Huong G, Hernandez, Marcos, Li, Lei, Herman, Christophe, Hastings, PJ, Bates, David, Harris, Reuben S, Miller, Kyle M, Rosenberg, Susan M
Publicado 2013

Colocalized targeting of TGF-β and PD-L1 by bintrafusp alfa elicits distinct antitumor responses

por Lan, Yan, Yeung, Tsz-Lun, Huang, Hui, Wegener, Ansgar A, Saha, Somdutta, Toister-Achituv, Mira, Jenkins, Molly H, Chiu, Li-Ya, Lazorchak, Adam, Tarcic, Ohad, Wang, Hong, Qi, Jin, Locke, George, Kalimi, Doron, Qin, Guozhong, Marelli, Bo, Yu, Huakui, Gross, Alec W, Derner, Melissa G, Soloviev, Maria, Botte, Mathieu, Sircar, Aroop, Ma, Hong, Sood, Vanita D, Zhang, Dong, Jiang, Feng, Lo, Kin-Ming
Publicado 2022