PRIMA-1(met) (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms

por Li, Xiao-Lan, Zhou, Jianbiao, Chan, Zit-Liang, Chooi, Jing-Yuan, Chen, Zhi-Rong, Chng, Wee-Joo
Publicado 2015

NF-κB promotes the stem-like properties of leukemia cells by activation of LIN28B

por Zhou, Jianbiao, Chooi, Jing-Yuan, Ching, Ying Qing, Quah, Jessie Yiying, Toh, Sabrina Hui-Min, Ng, Yvonne, Tan, Tuan Zea, Chng, Wee-Joo
Publicado 2018

A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase

por Zhou, Jianbiao, Toh, Sabrina Hui-Min, Chan, Zit-Liang, Quah, Jessie Yiying, Chooi, Jing-Yuan, Tan, Tuan Zea, Chong, Phyllis S. Y., Zeng, Qi, Chng, Wee-Joo
Publicado 2018

Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia

por Zhou, Jianbiao, Bi, Chonglei, Ching, Ying Qing, Chooi, Jing-Yuan, Lu, Xiao, Quah, Jessie Yiying, Toh, Sabrina Hui-Min, Chan, Zit-Liang, Tan, Tuan Zea, Chong, Phyllis SY, Chng, Wee-Joo
Publicado 2017

ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia

por Zhou, Jianbiao, Quah, Jessie Yiying, Ng, Yvonne, Chooi, Jing-Yuan, Toh, Sabrina Hui-Min, Lin, Baohong, Tan, Tuan Zea, Hosoi, Hiroki, Osato, Motomi, Seet, Qihui, Ooi, A.G. Lisa, Lindmark, Bertil, McHale, Mark, Chng, Wee-Joo
Publicado 2019

Myeloma-specific superenhancers affect genes of biological and clinical relevance in myeloma

por Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Wong, Regina Wan Ju, Chooi, Jing-Yuan, Lim, Julia Sze Lynn, Sanda, Takaomi, Ooi, Melissa, De Mel, Sanjay, Soekojo, Cinnie, Chen, Yongxia, Zhang, Enfan, Cai, Zhen, Shen, Peng, Ruan, Jian, Chng, Wee-Joo
Publicado 2021

Determinants of response to daratumumab in Epstein-Barr virus-positive natural killer and T-cell lymphoma

por Mustafa, Nurulhuda, Nee, Adina Huey Fang, Chooi, Jing Yuan, Toh, Sabrina Hui Min, Chung, Tae-Hoon, Selvarajan, Viknesvaran, Fan, Shuangyi, Ng, Siok Bian, Poon, Michelle, Chan, Esther, Lee, Joanne, Chee, Yen Lin, Jeyasekharan, Anand D, Zhou, Longen, Yang, Jennifer, Chng, Wee Joo
Publicado 2021

Super Enhancer-Mediated Upregulation of HJURP Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

por Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Chen, Yongxia, Chooi, Jing-Yuan, Sanda, Takaomi, Fullwood, Melissa J., Xiong, Sinan, Toh, Sabrina H.M., Balan, Kalpnaa, Wong, Regina W.J., Lim, Julia S.L., Zhang, Enfan, Cai, Zhen, Shen, Peng, Chng, Wee Joo
Publicado 2022