Neurodegenerative changes initiated by presynaptic dysfunction

por Yasuda, Toru, Nakata, Yasuto, Choong, Chi-Jing, Mochizuki, Hideki
Publicado 2013

Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein

por Araki, Katsuya, Yagi, Naoto, Aoyama, Koki, Choong, Chi-Jing, Hayakawa, Hideki, Fujimura, Harutoshi, Nagai, Yoshitaka, Goto, Yuji, Mochizuki, Hideki
Publicado 2019

New 5-Aryl-Substituted 2-Aminobenzamide-Type HDAC Inhibitors with a Diketopiperazine Group and Their Ameliorating Effects on Ischemia-Induced Neuronal Cell Death

por Hirata, Yoshiyuki, Sasaki, Tsutomu, Kanki, Hideaki, Choong, Chi-Jing, Nishiyama, Kumiko, Kubo, Genki, Hotei, Ayana, Taniguchi, Masahiko, Mochizuki, Hideki, Uesato, Shinichi
Publicado 2018

Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson’s disease

por Uehara, Takuya, Choong, Chi-Jing, Nakamori, Masayuki, Hayakawa, Hideki, Nishiyama, Kumiko, Kasahara, Yuuya, Baba, Kousuke, Nagata, Tetsuya, Yokota, Takanori, Tsuda, Hiroshi, Obika, Satoshi, Mochizuki, Hideki
Publicado 2019

Synchrotron FTIR micro-spectroscopy for structural analysis of Lewy bodies in the brain of Parkinson’s disease patients

por Araki, Katsuya, Yagi, Naoto, Ikemoto, Yuka, Yagi, Hisashi, Choong, Chi-Jing, Hayakawa, Hideki, Beck, Goichi, Sumi, Hisae, Fujimura, Harutoshi, Moriwaki, Taro, Nagai, Yoshitaka, Goto, Yuji, Mochizuki, Hideki
Publicado 2015

Alternative mitochondrial quality control mediated by extracellular release

por Choong, Chi-Jing, Okuno, Tatsusada, Ikenaka, Kensuke, Baba, Kousuke, Hayakawa, Hideki, Koike, Masato, Yokota, Mutsumi, Doi, Junko, Kakuda, Keita, Takeuchi, Toshihide, Kuma, Akiko, Nakamura, Shuhei, Nagai, Yoshitaka, Nagano, Seiichi, Yoshimori, Tamotsu, Mochizuki, Hideki
Publicado 2020

Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson’s disease

por Hideshima, Makoto, Kimura, Yasuyoshi, Aguirre, César, Kakuda, Keita, Takeuchi, Toshihide, Choong, Chi-Jing, Doi, Junko, Nabekura, Kei, Yamaguchi, Keiichi, Nakajima, Kichitaro, Baba, Kousuke, Nagano, Seiichi, Goto, Yuji, Nagai, Yoshitaka, Mochizuki, Hideki, Ikenaka, Kensuke
Publicado 2022

Single injection of sustained-release prostacyclin analog ONO-1301-MS ameliorates hypoxic toxicity in the murine model of amyotrophic lateral sclerosis

por Tada, Satoru, Okuno, Tatsusada, Shimizu, Mikito, Sakai, Yoshiki, Sumi-Akamaru, Hisae, Kinoshita, Makoto, Yamashita, Kazuya, Sanda, Eri, Choong, Chi-Jing, Namba, Akiko, Sasaki, Tsutomu, Koda, Toru, Takata, Kazushiro, Miyagawa, Shigeru, Sawa, Yoshiki, Nakatsuji, Yuji, Mochizuki, Hideki
Publicado 2019

Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson’s disease-related fibril polymorphism

por Choong, Chi-Jing, Aguirre, César, Kakuda, Keita, Beck, Goichi, Nakanishi, Hiroki, Kimura, Yasuyoshi, Shimma, Shuichi, Nabekura, Kei, Hideshima, Makoto, Doi, Junko, Yamaguchi, Keiichi, Nakajima, Kichitaro, Wadayama, Tomoya, Hayakawa, Hideki, Baba, Kousuke, Ogawa, Kotaro, Takeuchi, Toshihide, Badawy, Shaymaa Mohamed Mohamed, Murayama, Shigeo, Nagano, Seiichi, Goto, Yuji, Miyanoiri, Yohei, Nagai, Yoshitaka, Mochizuki, Hideki, Ikenaka, Kensuke
Publicado 2023