Using Macrocyclic G‐Quadruplex Ligands to Decipher the Interactions Between Small Molecules and G‐Quadruplex DNA

por Andréasson, Måns, Bhuma, Naresh, Pemberton, Nils, Chorell, Erik
Publicado 2022

Parallel G-Quadruplex DNA Structures from Nuclear and Mitochondrial Genomes Trigger Emission Enhancement in a Nonfluorescent Nano-aggregated Fluorine–Boron-Based Dye

por Deiana, Marco, Chand, Karam, Chorell, Erik, Sabouri, Nasim
Publicado 2023

Macrocyclization of bis-indole quinolines for selective stabilization of G-quadruplex DNA structures

por Das, Rabindra Nath, Andréasson, Måns, Kumar, Rajendra, Chorell, Erik
Publicado 2020

A complementary chemical probe approach towards customized studies of G-quadruplex DNA structures in live cells

por Prasad, Bagineni, Doimo, Mara, Andréasson, Måns, L’Hôte, Valentin, Chorell, Erik, Wanrooij, Sjoerd
Publicado 2022

A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures

por Deiana, Marco, Obi, Ikenna, Andreasson, Måns, Tamilselvi, Shanmugam, Chand, Karam, Chorell, Erik, Sabouri, Nasim
Publicado 2021

Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner

por Sharma, Sandeep K., Chorell, Erik, Steneberg, Pär, Vernersson-Lindahl, Emma, Edlund, Helena, Wittung-Stafshede, Pernilla
Publicado 2015

Single injection of small-molecule amyloid accelerator results in cell death of nigral dopamine neurons in mice

por Chermenina, Maria, Chorell, Erik, Pokrzywa, Małgorzata, Antti, Henrik, Almqvist, Fredrik, Strömberg, Ingrid, Wittung-Stafshede, Pernilla
Publicado 2015

Subtle structural alterations in G-quadruplex DNA regulate site specificity of fluorescence light-up probes

por Kumar, Rajendra, Chand, Karam, Bhowmik, Sudipta, Das, Rabindra Nath, Bhattacharjee, Snehasish, Hedenström, Mattias, Chorell, Erik
Publicado 2020

The Relation Between Position and Chemical Composition of Bis‐Indole Substituents Determines Their Interactions with G‐Quadruplex DNA

por Prasad, Bagineni, Das, Rabindra Nath, Jamroskovic, Jan, Kumar, Rajendra, Hedenström, Mattias, Sabouri, Nasim, Chorell, Erik
Publicado 2020

Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson’s disease

por Pokrzywa, Małgorzata, Pawełek, Katarzyna, Kucia, Weronika Elżbieta, Sarbak, Szymon, Chorell, Erik, Almqvist, Fredrik, Wittung-Stafshede, Pernilla
Publicado 2017

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication

por Obi, Ikenna, Rentoft, Matilda, Singh, Vandana, Jamroskovic, Jan, Chand, Karam, Chorell, Erik, Westerlund, Fredrik, Sabouri, Nasim
Publicado 2020

Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts

por Chorell, Erik, Andersson, Emma, Evans, Margery L., Jain, Neha, Götheson, Anna, Åden, Jörgen, Chapman, Matthew R., Almqvist, Fredrik, Wittung-Stafshede, Pernilla
Publicado 2015

Design and Synthesis of Fluorescent Pilicides and Curlicides: Bioactive Tools to Study Bacterial Virulence Mechanisms

por Chorell–, Erik, Pinkner, Jerome S, Bengtsson, Christoffer, Edvinsson, Sofie, Cusumano, Corinne K, Rosenbaum, Erik, Johansson, Lennart B Å, Hultgren, Scott J, Almqvist, Fredrik
Publicado 2012

Pilicide ec240 Disrupts Virulence Circuits in Uropathogenic Escherichia coli

por Greene, Sarah E., Pinkner, Jerome S., Chorell, Erik, Dodson, Karen W., Shaffer, Carrie L., Conover, Matt S., Livny, Jonathan, Hadjifrangiskou, Maria, Almqvist, Fredrik, Hultgren, Scott J.
Publicado 2014

Mechanisms of Protein Oligomerization: Inhibitor of Functional Amyloids Templates α-Synuclein Fibrillation

por Horvath, Istvan, Weise, Christoph F., Andersson, Emma K., Chorell, Erik, Sellstedt, Magnus, Bengtsson, Christoffer, Olofsson, Anders, Hultgren, Scott J., Chapman, Matthew, Wolf-Watz, Magnus, Almqvist, Fredrik, Wittung-Stafshede, Pernilla
Publicado 2012

A 2-Pyridone-Amide Inhibitor Targets the Glucose Metabolism Pathway of Chlamydia trachomatis

por Engström, Patrik, Krishnan, K. Syam, Ngyuen, Bidong D., Chorell, Erik, Normark, Johan, Silver, Jim, Bastidas, Robert J., Welch, Matthew D., Hultgren, Scott J., Wolf-Watz, Hans, Valdivia, Raphael H., Almqvist, Fredrik, Bergström, Sven
Publicado 2014

Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells

por Doimo, Mara, Chaudhari, Namrata, Abrahamsson, Sanna, L’Hôte, Valentin, Nguyen, Tran V H, Berner, Andreas, Ndi, Mama, Abrahamsson, Alva, Das, Rabindra Nath, Aasumets, Koit, Goffart, Steffi, Pohjoismäki, Jaakko L O, López, Marcela Dávila, Chorell, Erik, Wanrooij, Sjoerd
Publicado 2023

Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA

por Good, James A.D., Andersson, Christopher, Hansen, Sabine, Wall, Jessica, Krishnan, K. Syam, Begum, Afshan, Grundström, Christin, Niemiec, Moritz S., Vaitkevicius, Karolis, Chorell, Erik, Wittung-Stafshede, Pernilla, Sauer, Uwe H., Sauer-Eriksson, A. Elisabeth, Almqvist, Fredrik, Johansson, Jörgen
Publicado 2016

Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization

por Jamroskovic, Jan, Doimo, Mara, Chand, Karam, Obi, Ikenna, Kumar, Rajendra, Brännström, Kristoffer, Hedenström, Mattias, Nath Das, Rabindra, Akhunzianov, Almaz, Deiana, Marco, Kasho, Kazutoshi, Sulis Sato, Sebastian, Pourbozorgi, Parham L., Mason, James E., Medini, Paolo, Öhlund, Daniel, Wanrooij, Sjoerd, Chorell, Erik, Sabouri, Nasim
Publicado 2020