Mitochondrial Lon-induced mitophagy benefits hypoxic resistance via Ca(2+)-dependent FUNDC1 phosphorylation at the ER-mitochondria interface

por Ponneri Babuharisankar, Ananth, Kuo, Cheng-Liang, Chou, Han-Yu, Tangeda, Vidhya, Fan, Chi-Chen, Chen, Chung-Hsing, Kao, Yung-Hsi, Lee, Alan Yueh-Luen
Publicado 2023

Lon upregulation contributes to cisplatin resistance by triggering NCLX-mediated mitochondrial Ca(2+) release in cancer cells

por Tangeda, Vidhya, Lo, Yu Kang, Babuharisankar, Ananth Ponneri, Chou, Han-Yu, Kuo, Cheng-Liang, Kao, Yung-Hsi, Lee, Alan Yueh-Luen, Chang, Jang-Yang
Publicado 2022

Bufalin induced apoptosis in SCC-4 human tongue cancer cells by decreasing Bcl-2 and increasing Bax expression via the mitochondria-dependent pathway

por Chou, Han-Yu, Chueh, Fu-Shin, Ma, Yi-Shih, Wu, Rick Sai-Chuen, Liao, Ching-Lung, Chu, Yung-Lin, Fan, Ming-Jen, Huang, Wen-Wen, Chung, Jing-Gung
Publicado 2017

Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?

por Kuo, Cheng-Liang, Ponneri Babuharisankar, Ananth, Lin, Ying-Chen, Lien, Hui-Wen, Lo, Yu Kang, Chou, Han-Yu, Tangeda, Vidhya, Cheng, Li-Chun, Cheng, An Ning, Lee, Alan Yueh-Luen
Publicado 2022

Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1–mediated immunoescape via STING-IFN signaling and extracellular vesicles

por Cheng, An Ning, Cheng, Li-Chun, Kuo, Cheng-Liang, Lo, Yu Kang, Chou, Han-Yu, Chen, Chung-Hsing, Wang, Yi-Hao, Chuang, Tsung-Hsien, Cheng, Shih-Jung, Lee, Alan Yueh-Luen
Publicado 2020

A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment

por Kuo, Cheng-Liang, Chou, Han-Yu, Lien, Hui-Wen, Yeh, Chia-An, Wang, Jing-Rong, Chen, Chung-Hsing, Fan, Chi-Chen, Hsu, Chih-Ping, Kao, Ting-Yu, Ko, Tai-Ming, Lee, Alan Yueh-Luen
Publicado 2022

Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity

por Sung, Ya-Ju, Kao, Ting-Yu, Kuo, Cheng-Liang, Fan, Chi-Chen, Cheng, An Ning, Fang, Wei-Cheng, Chou, Han-Yu, Lo, Yu-Kang, Chen, Chung-Hsing, Jiang, Shih Sheng, Chang, I-Shou, Hsu, Chun-Hua, Lee, Jin-Ching, Lee, Alan Yueh-Luen
Publicado 2018