TGFβ-Stimulated MicroRNA-21 Utilizes PTEN to Orchestrate AKT/mTORC1 Signaling for Mesangial Cell Hypertrophy and Matrix Expansion

por Dey, Nirmalya, Ghosh-Choudhury, Nandini, Kasinath, Balakuntalam S., Choudhury, Goutam Ghosh
Publicado 2012

Oncoprotein DJ-1 interacts with mTOR complexes to effect transcription factor Hif1α-dependent expression of collagen I (α2) during renal fibrosis

por Das, Falguni, Ghosh-Choudhury, Nandini, Maity, Soumya, Kasinath, Balakuntalam S., Choudhury, Goutam Ghosh
Publicado 2022

TGFβ-Induced Deptor Suppression Recruits mTORC1 and Not mTORC2 to Enhance Collagen I (α2) Gene Expression

por Das, Falguni, Bera, Amit, Ghosh-Choudhury, Nandini, Abboud, Hanna E., Kasinath, Balakuntalam S., Choudhury, Goutam Ghosh
Publicado 2014

Akt2 causes TGFβ-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression

por Das, Falguni, Ghosh-Choudhury, Nandini, Lee, Doug Yoon, Gorin, Yves, Kasinath, Balakuntalam S., Choudhury, Goutam Ghosh
Publicado 2018

Rapamycin selectively alters serum chemistry in diabetic mice

por Tabatabai-Mir, Hooman, Sataranatarajan, Kavithalakshmi, Lee, Hak Joo, Bokov, Alex F., Fernandez, Elizabeth, Diaz, Vivian, Choudhury, Goutam Ghosh, Richardson, Arlan, Kasinath, Balakuntalam S.
Publicado 2012

Nox4 is a Target for Tuberin Deficiency Syndrome

por Shi, Qian, Viswanadhapalli, Suryavathi, Friedrichs, William E., Velagapudi, Chakradhar, Szyndralewiez, Cédric, Bansal, Shweta, Bhat, Manzoor A., Choudhury, Goutam Ghosh, Abboud, Hanna E.
Publicado 2018

microRNA-21 Governs TORC1 Activation in Renal Cancer Cell Proliferation and Invasion

por Dey, Nirmalya, Das, Falguni, Ghosh-Choudhury, Nandini, Mandal, Chandi Charan, Parekh, Dipen J., Block, Karen, Kasinath, Balakuntalam S., Abboud, Hanna E., Choudhury, Goutam Ghosh
Publicado 2012

Mammalian Target of Rapamycin Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury

por Eid, Assaad A., Ford, Bridget M., Bhandary, Basant, de Cassia Cavaglieri, Rita, Block, Karen, Barnes, Jeffrey L., Gorin, Yves, Choudhury, Goutam Ghosh, Abboud, Hanna E.
Publicado 2013

Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging‐related kidney injury

por Lee, Hak Joo, Donati, Andrew, Feliers, Denis, Sun, Yuyang, Ding, Yanli, Madesh, Muniswamy, Salmon, Adam B., Ikeno, Yuji, Ross, Corinna, O'Connor, Christopher L., Ju, Wenjun, Bitzer, Markus, Chen, Yidong, Choudhury, Goutam Ghosh, Singh, Brij B., Sharma, Kumar, Kasinath, Balakuntalam S.
Publicado 2021