ATM is activated by ATP depletion and modulates mitochondrial function through NRF1

por Chow, Hei-Man, Cheng, Aifang, Song, Xuan, Swerdel, Mavis R., Hart, Ronald P., Herrup, Karl
Publicado 2019

A peptide inhibitor that rescues polyglutamine-induced synaptic defects and cell death through suppressing RNA and protein toxicities

por Peng, Shaohong Isaac, Leong, Lok I., Sun, Jacquelyne Ka-Li, Chen, Zhefan Stephen, Chow, Hei-Man, Chan, Ho Yin Edwin
Publicado 2022

Low‐Density Lipoprotein Receptor‐Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes

por Chow, Hei‐Man, Sun, Jacquelyne Ka‐Li, Hart, Ronald P., Cheng, Kenneth King‐Yip, Hung, Clara H. L., Lau, Tsun‐Ming, Kwan, Kin‐Ming
Publicado 2021

Chronic alcohol metabolism results in DNA repair infidelity and cell cycle‐induced senescence in neurons

por Sun, Jacquelyne Ka‐Li, Wu, Deng, Wong, Genper Chi‐Ngai, Lau, Tsun‐Ming, Yang, Meigui, Hart, Ronald P., Kwan, Kin‐Ming, Chan, Ho Yin Edwin, Chow, Hei‐Man
Publicado 2023

CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration

por Peng, Shaohong, Guo, Pei, Lin, Xiao, An, Ying, Sze, Kong Hung, Lau, Matthew Ho Yan, Chen, Zhefan Stephen, Wang, Qianwen, Li, Wen, Sun, Jacquelyne Ka-Li, Ma, Sum Yi, Chan, Ting-Fung, Lau, Kwok-Fai, Ngo, Jacky Chi Ki, Kwan, Kin Ming, Wong, Chun-Ho, Lam, Sik Lok, Zimmerman, Steven C., Tuccinardi, Tiziano, Zuo, Zhong, Au-Yeung, Ho Yu, Chow, Hei-Man, Chan, Ho Yin Edwin
Publicado 2021