Towards a Functional Cure of HIV-1: Insight Into the Chromatin Landscape of the Provirus

por Janssens, Julie, Bruggemans, Anne, Christ, Frauke, Debyser, Zeger
Publicado 2021

Determinants of Retroviral Integration and Implications for Gene Therapeutic MLV—Based Vectors and for a Cure for HIV-1 Infection

por Pellaers, Eline, Bhat, Anayat, Christ, Frauke, Debyser, Zeger
Publicado 2022

Insight into HIV-2 latency may disclose strategies for a cure for HIV-1 infection

por Saleh, Suha, Vranckx, Lenard, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger
Publicado 2017

Insight in HIV Integration Site Selection Provides a Block-and-Lock Strategy for a Functional Cure of HIV Infection

por Debyser, Zeger, Vansant, Gerlinde, Bruggemans, Anne, Janssens, Julie, Christ, Frauke
Publicado 2018

Synthesis and Anti-HIV Profile of a Novel Tetrahydroindazolylbenzamide Derivative Obtained by Oxazolone Chemistry

por Scala, Angela, Piperno, Anna, Micale, Nicola, Christ, Frauke, Debyser, Zeger
Publicado 2018

PB1704: LEDGF/P75 ASSOCIATED WITH CHEMORESISTANCE IN MIXED-LINEAGE LEUKEMIA

por Akele, Muluembet, Belle, Siska Van, Canella, Alessandro, Christ, Frauke, Debyser, Zeger
Publicado 2023

Cellular Cofactors of Lentiviral Integrase: From Target Validation to Drug Discovery

por Taltynov, Oliver, Desimmie, Belete A., Demeulemeester, Jonas, Christ, Frauke, Debyser, Zeger
Publicado 2012

Role of Transportin-SR2 in HIV-1 Nuclear Import

por Tabasi, Maryam, Nombela, Ivan, Janssens, Julie, Lahousse, Adrien P., Christ, Frauke, Debyser, Zeger
Publicado 2021

A Symmetric Region of the HIV-1 Integrase Dimerization Interface Is Essential for Viral Replication

por Serrao, Erik, Thys, Wannes, Demeulemeester, Jonas, Al-Mawsawi, Laith Q., Christ, Frauke, Debyser, Zeger, Neamati, Nouri
Publicado 2012

Inhibitors of the integrase–transportin-SR2 interaction block HIV nuclear import

por Demeulemeester, Jonas, Blokken, Jolien, De Houwer, Stéphanie, Dirix, Lieve, Klaassen, Hugo, Marchand, Arnaud, Chaltin, Patrick, Christ, Frauke, Debyser, Zeger
Publicado 2018

2-Hydroxyisoquinoline-1,3(2H, 4H)diones (HQDs), novel inhibitors of the HIV integrase catalytic activity with a high barrier to resistance

por Christ, Frauke, Demeulemeester, Jonas, Desimmie, Belete, Suchaud, Virginie, Taltynov, Oliver, Lion, Cedric, Bailly, Fabrice, Strelkov, Sergei, Cotelle, Philipe, Debyser, Zeger
Publicado 2013

Impact of LEDGIN treatment during virus production on residual HIV-1 transcription

por Vansant, Gerlinde, Vranckx, Lenard S., Zurnic, Irena, Van Looveren, Dominique, Van de Velde, Paulien, Nobles, Christopher, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger
Publicado 2019

Interplay between HIV Entry and Transportin-SR2 Dependency

por Thys, Wannes, De Houwer, Stéphanie, Demeulemeester, Jonas, Taltynov, Oliver, Vancraenenbroeck, Renée, Gérard, Melanie, De Rijck, Jan, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger
Publicado 2011

LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs

por Schrijvers, Rik, De Rijck, Jan, Demeulemeester, Jonas, Adachi, Noritaka, Vets, Sofie, Ronen, Keshet, Christ, Frauke, Bushman, Frederic D., Debyser, Zeger, Gijsbers, Rik
Publicado 2012

Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach

por Sirous, Hajar, Chemi, Giulia, Gemma, Sandra, Butini, Stefania, Debyser, Zeger, Christ, Frauke, Saghaie, Lotfollah, Brogi, Simone, Fassihi, Afshin, Campiani, Giuseppe, Brindisi, Margherita
Publicado 2019

Phenotyping of Rare CFTR Mutations Reveals Distinct Trafficking and Functional Defects

por Ensinck, Marjolein, De Keersmaecker, Liesbeth, Heylen, Lise, Ramalho, Anabela S., Gijsbers, Rik, Farré, Ricard, De Boeck, Kris, Christ, Frauke, Debyser, Zeger, Carlon, Marianne S.
Publicado 2020

Correction: LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs

por Schrijvers, Rik, Rijck, Jan De, Demeulemeester, Jonas, Adachi, Noritaka, Vets, Sofie, Ronen, Keshet, Christ, Frauke, Bushman, Frederic D., Debyser, Zeger, Gijsbers, Rik
Publicado 2020

Novel CFTR modulator combinations maximise rescue of G85E and N1303K in rectal organoids

por Ensinck, Marjolein M., De Keersmaecker, Liesbeth, Ramalho, Anabela S., Cuyx, Senne, Van Biervliet, Stephanie, Dupont, Lieven, Christ, Frauke, Debyser, Zeger, Vermeulen, François, Carlon, Marianne S.
Publicado 2022

Virus Evolution Reveals an Exclusive Role for LEDGF/p75 in Chromosomal Tethering of HIV

por Hombrouck, Anneleen, De Rijck, Jan, Hendrix, Jelle, Vandekerckhove, Linos, Voet, Arnout, Maeyer, Marc De, Witvrouw, Myriam, Engelborghs, Yves, Christ, Frauke, Gijsbers, Rik, Debyser, Zeger
Publicado 2007

Dynamic Oligomerization of Integrase Orchestrates HIV Nuclear Entry

por Borrenberghs, Doortje, Dirix, Lieve, De Wit, Flore, Rocha, Susana, Blokken, Jolien, De Houwer, Stéphanie, Gijsbers, Rik, Christ, Frauke, Hofkens, Johan, Hendrix, Jelle, Debyser, Zeger
Publicado 2016