Development of a Novel Vaccine Containing Binary Toxin for the Prevention of Clostridium difficile Disease with Enhanced Efficacy against NAP1 Strains

por Secore, Susan, Wang, Su, Doughtry, Julie, Xie, Jinfu, Miezeiewski, Matt, Rustandi, Richard R., Horton, Melanie, Xoconostle, Rachel, Wang, Bei, Lancaster, Catherine, Kristopeit, Adam, Wang, Sheng-Ching, Christanti, Sianny, Vitelli, Salvatore, Gentile, Marie-Pierre, Goerke, Aaron, Skinner, Julie, Strable, Erica, Thiriot, David S., Bodmer, Jean-Luc, Heinrichs, Jon H.
Publicado 2017

Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly

por Xu, Xingjian, Godoy-Ruiz, Raquel, Adipietro, Kaylin A., Peralta, Christopher, Ben-Hail, Danya, Varney, Kristen M., Cook, Mary E., Roth, Braden M., Wilder, Paul T., Cleveland, Thomas, Grishaev, Alexander, Neu, Heather M., Michel, Sarah L. J., Yu, Wenbo, Beckett, Dorothy, Rustandi, Richard R., Lancaster, Catherine, Loughney, John W., Kristopeit, Adam, Christanti, Sianny, Olson, Jessica W., MacKerell, Alexander D., des Georges, Amedee, Pozharski, Edwin, Weber, David J.
Publicado 2020