A genetic researcher’s devil’s dilemma: Warn relatives about their genetic risk or respect confidentiality agreements with research participants?

por van den Heuvel, Lieke M., Maeckelberghe, Els L. M., Ploem, M. Corrette, Christiaans, Imke
Publicado 2021

How to inform at‐risk relatives? Attitudes of 1379 Dutch patients, relatives, and members of the general population

por Marleen van den Heuvel, Lieke, Stemkens, Daphne, van Zelst‐Stams, Wendy A. G., Willeboordse, Floor, Christiaans, Imke
Publicado 2019

Feasibility of an Assessment Tool for Children’s Competence to Consent to Predictive Genetic Testing: a Pilot Study

por Hein, Irma M., Troost, Pieter W., Lindeboom, Robert, Christiaans, Imke, Grisso, Thomas, van Goudoever, Johannes B., Lindauer, Ramón J. L.
Publicado 2015

A tailored approach towards informing relatives at risk of inherited cardiac conditions: study protocol for a randomised controlled trial

por van den Heuvel, Lieke M, Hoedemaekers, Yvonne M, Baas, Annette F, van Tintelen, J Peter, Smets, Ellen M A, Christiaans, Imke
Publicado 2019

Long-Term Follow-Up Study on the Uptake of Genetic Counseling and Predictive DNA Testing in Inherited Cardiac Conditions

por van den Heuvel, Lieke M., van Teijlingen, Maxiem O., van der Roest, Wilma, van Langen, Irene M., Smets, Ellen M.A., van Tintelen, J. Peter, Christiaans, Imke
Publicado 2020

Targeted sequence capture and GS-FLX Titanium sequencing of 23 hypertrophic and dilated cardiomyopathy genes: implementation into diagnostics

por Mook, Olaf R F, Haagmans, Martin A, Soucy, Jean-François, van de Meerakker, Judith B A, Baas, Frank, Jakobs, Marja E, Hofman, Nynke, Christiaans, Imke, Lekanne Deprez, Ronald H, Mannens, Marcel M A M
Publicado 2013

Genetic Evaluation in a Cohort of 126 Dutch Pulmonary Arterial Hypertension Patients

por van den Heuvel, Lieke M., Jansen, Samara M. A., Alsters, Suzanne I. M., Post, Marco C., van der Smagt, Jasper J., Handoko-De Man, Frances S., van Tintelen, J. Peter, Gille, Hans, Christiaans, Imke, Vonk Noordegraaf, Anton, Bogaard, HarmJan, Houweling, Arjan C.
Publicado 2020

Reclassification of a likely pathogenic Dutch founder variant in KCNH2; implications of reduced penetrance

por Copier, Jaël S, Bootsma, Marianne, Ng, Chai A, Wilde, Arthur A M, Bertels, Robin A, Bikker, Hennie, Christiaans, Imke, van der Crabben, Saskia N, Hol, Janna A, Koopmann, Tamara T, Knijnenburg, Jeroen, Lommerse, Aafke A J, van der Smagt, Jasper J, Bezzina, Connie R, Vandenberg, Jamie I, Verkerk, Arie O, Barge-Schaapveld, Daniela Q C M, Lodder, Elisabeth M
Publicado 2022

Heritability in genetic heart disease: the role of genetic background

por Jansweijer, Joeri A, van Spaendonck-Zwarts, Karin Y, Tanck, Michael W T, van Tintelen, J Peter, Christiaans, Imke, van der Smagt, Jasper J, Vermeer, Alexa M C, Bos, J Martijn, Moss, Arthur J, Swan, Heikki, Priori, Sylvia G, Rydberg, Annika, Tfelt-Hansen, Jacob, Ackerman, Michael J, Olivotto, Iacopo, Charron, Philippe, Gimeno, Juan R, van den Berg, Maarten P, Wilde, Arthur AM, Pinto, Yigal M
Publicado 2019

Untargeted Metabolomics Identifies Potential Hypertrophic Cardiomyopathy Biomarkers in Carriers of MYBPC3 Founder Variants

por Jansen, Mark, Schuldt, Maike, van Driel, Beau O., Schmidt, Amand F., Christiaans, Imke, van der Crabben, Saskia N., Hoedemaekers, Yvonne M., Dooijes, Dennis, Jongbloed, Jan D. H., Boven, Ludolf G., Deprez, Ronald H. Lekanne, Wilde, Arthur A. M., Jans, Judith J. M., van der Velden, Jolanda, de Boer, Rudolf A., van Tintelen, J. Peter, Asselbergs, Folkert W., Baas, Annette F.
Publicado 2023

Genetic Burden of TNNI3K in Diagnostic Testing of Patients With Dilated Cardiomyopathy and Supraventricular Arrhythmias

por Pham, Caroline, Andrzejczyk, Karolina, Jurgens, Sean J., Lekanne Deprez, Ronald, Palm, Kaylin C.A., Vermeer, Alexa M.C., Nijman, Janneke, Christiaans, Imke, Barge-Schaapveld, Daniela Q.C.M., van Dessel, Pascal F.H.M., Beekman, Leander, Choi, Seung Hoan, Lubitz, Steven A., Skoric-Milosavljevic, Doris, van den Bersselaar, Lisa, Jansen, Philip R., Copier, Jaël S., Ellinor, Patrick T., Wilde, Arthur A.M., Bezzina, Connie R., Lodder, Elisabeth M.
Publicado 2023

The genetic basis of apparently idiopathic ventricular fibrillation: a retrospective overview

por Verheul, Lisa M, van der Ree, Martijn H, Groeneveld, Sanne A, Mulder, Bart A, Christiaans, Imke, Kapel, Gijs F L, Alings, Marco, Bootsma, Marianne, Barge-Schaapveld, Daniela Q C M, Balt, Jippe C, Yap, Sing-Chien, Krapels, Ingrid P C, Ter Bekke, Rachel M A, Volders, Paul G A, van der Crabben, Saskia N, Postema, Pieter G, Wilde, Arthur A M, Dooijes, Dennis, Baas, Annette F, Hassink, Rutger J
Publicado 2023

Lack of evidence for a causal role of CALR3 in monogenic cardiomyopathy

por Verhagen, Judith M. A., Veldman, Job H., van der Zwaag, Paul A., von der Thüsen, Jan H., Brosens, Erwin, Christiaans, Imke, Dooijes, Dennis, Helderman-van den Enden, Apollonia T. J. M., Lekanne Deprez, Ronald H., Michels, Michelle, van Mil, Anneke M., Oldenburg, Rogier A., van der Smagt, Jasper J., van den Wijngaard, Arthur, Wessels, Marja W., Hofstra, Robert M. W., van Slegtenhorst, Marjon A., Jongbloed, Jan D. H., van de Laar, Ingrid M. B. H.
Publicado 2018

Genetic Evaluation of A Nation-Wide Dutch Pediatric DCM Cohort: The Use of Genetic Testing in Risk Stratification

por van der Meulen, Marijke H., Herkert, Johanna C., den Boer, Susanna L., du Marchie Sarvaas, Gideon J., Blom, Nico A., ten Harkel, Arend D.J., Breur, Hans M.P.J., Rammeloo, Lukas A.J., Tanke, Ronald B., Marcelis, Carlo, van de Laar, Ingrid M.B.H., Verhagen, Judith M.A., Lekanne dit Deprez, Ronald H., Barge-Schaapveld, Daniela Q.C.M., Baas, Annette F., Sammani, Arjan, Christiaans, Imke, van Tintelen, J. Peter, Dalinghaus, Michiel
Publicado 2022

A mutation update for the FLNC gene in myopathies and cardiomyopathies

por Verdonschot, Job A. J., Vanhoutte, Els K., Claes, Godelieve R. F., Helderman‐van den Enden, Apollonia T. J. M., Hoeijmakers, Janneke G. J., Hellebrekers, Debby M. E. I., de Haan, Amber, Christiaans, Imke, Lekanne Deprez, Ronald H., Boen, Hanne M., van Craenenbroeck, Emeline M., Loeys, Bart L., Hoedemaekers, Yvonne M., Marcelis, Carlo, Kempers, Marlies, Brusse, Esther, van Waning, Jaap I., Baas, Annette F., Dooijes, Dennis, Asselbergs, Folkert W., Barge‐Schaapveld, Daniela Q. C. M., Koopman, Pieter, van den Wijngaard, Arthur, Heymans, Stephane R. B., Krapels, Ingrid P. C., Brunner, Han G.
Publicado 2020

Large scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy

por Tadros, Rafik, Zheng, Sean L, Grace, Christopher, Jordà, Paloma, Francis, Catherine, Jurgens, Sean J, Thomson, Kate L, Harper, Andrew R, Ormondroyd, Elizabeth, West, Dominique M, Xu, Xiao, Theotokis, Pantazis I, Buchan, Rachel J, McGurk, Kathryn A, Mazzarotto, Francesco, Boschi, Beatrice, Pelo, Elisabetta, Lee, Michael, Noseda, Michela, Varnava, Amanda, Vermeer, Alexa MC, Walsh, Roddy, Amin, Ahmad S, van Slegtenhorst, Marjon A, Roslin, Nicole, Strug, Lisa J, Salvi, Erika, Lanzani, Chiara, de Marvao, Antonio, Roberts, Jason D, Tremblay-Gravel, Maxime, Giraldeau, Genevieve, Cadrin-Tourigny, Julia, L'Allier, Philippe L, Garceau, Patrick, Talajic, Mario, Pinto, Yigal M, Rakowski, Harry, Pantazis, Antonis, Baksi, John, Halliday, Brian P, Prasad, Sanjay K, Barton, Paul JR, O'Regan, Declan P, Cook, Stuart A, de Boer, Rudolf A, Christiaans, Imke, Michels, Michelle, Kramer, Christopher M, Ho, Carolyn Y, Neubauer, Stefan, Matthews, Paul M, Wilde, Arthur A, Tardif, Jean-Claude, Olivotto, Iacopo, Adler, Arnon, Goel, Anuj, Ware, James S, Bezzina, Connie R, Watkins, Hugh
Publicado 2023

Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect

por Tadros, Rafik, Francis, Catherine, Xu, Xiao, Vermeer, Alexa M. C., Harper, Andrew R., Huurman, Roy, Bisabu, Ken Kelu, Walsh, Roddy, Hoorntje, Edgar T., te Rijdt, Wouter P., Buchan, Rachel J., van Velzen, Hannah G., van Slegtenhorst, Marjon A., Vermeulen, Jentien M., Offerhaus, Joost Allard, Bai, Wenjia, de Marvao, Antonio, Lahrouchi, Najim, Beekman, Leander, Karper, Jacco C., Veldink, Jan H., Kayvanpour, Elham, Pantazis, Antonis, Baksi, A. John, Whiffin, Nicola, Mazzarotto, Francesco, Sloane, Geraldine, Suzuki, Hideaki, Schneider-Luftman, Deborah, Elliott, Paul, Richard, Pascale, Ader, Flavie, Villard, Eric, Lichtner, Peter, Meitinger, Thomas, Tanck, Michael W. T., van Tintelen, J. Peter, Thain, Andrew, McCarty, David, Hegele, Robert A., Roberts, Jason D., Amyot, Julie, Dubé, Marie-Pierre, Cadrin-Tourigny, Julia, Giraldeau, Geneviève, L’Allier, Philippe L., Garceau, Patrick, Tardif, Jean-Claude, Boekholdt, S. Matthijs, Lumbers, R. Thomas, Asselbergs, Folkert W., Barton, Paul J. R., Cook, Stuart A., Prasad, Sanjay K., O’Regan, Declan P., van der Velden, Jolanda, Verweij, Karin J. H., Talajic, Mario, Lettre, Guillaume, Pinto, Yigal M., Meder, Benjamin, Charron, Philippe, de Boer, Rudolf A., Christiaans, Imke, Michels, Michelle, Wilde, Arthur A. M., Watkins, Hugh, Matthews, Paul M., Ware, James S., Bezzina, Connie R.
Publicado 2021