Genetic risk score and risk of stage 3 chronic kidney disease

por Ma, Jiantao, Yang, Qiong, Hwang, Shih-Jen, Fox, Caroline S., Chu, Audrey Y.
Publicado 2017

Association of APOE polymorphism with chronic kidney disease in a nationally representative sample: a Third National Health and Nutrition Examination Survey (NHANES III) Genetic St...

por Chu, Audrey Y, Parekh, Rulan S, Astor, Brad C, Coresh, Josef, Berthier-Schaad, Yvette, Smith, Michael W, Shuldiner, Alan R, Kao, Wen Hong L
Publicado 2009

Integrating Genetic, Transcriptional and Biological Information Provides Insights into Obesity

por Wang, Lan, Perez, Jeremiah, Heard-Costa, Nancy, Chu, Audrey Y., Joehanes, Roby, Munson, Peter J., Levy, Daniel, Fox, Caroline S., Cupples, L. Adrienne, Liu, Ching-Ti
Publicado 2018

Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk

por Harlow, Charli E, Patel, Vickas V, Waterworth, Dawn M, Wood, Andrew R, Beaumont, Robin N, Ruth, Katherine S, Tyrrell, Jessica, Oguro-Ando, Asami, Chu, Audrey Y, Frayling, Timothy M
Publicado 2022

Atherogenic Lipoprotein Determinants of Cardiovascular Disease and Residual Risk Among Individuals With Low Low‐Density Lipoprotein Cholesterol

por Lawler, Patrick R., Akinkuolie, Akintunde O., Chu, Audrey Y., Shah, Svati H., Kraus, William E., Craig, Damian, Padmanabhan, Latha, Glynn, Robert J., Ridker, Paul M, Chasman, Daniel I., Mora, Samia
Publicado 2017

Lactate and Risk of Incident Diabetes in a Case-Cohort of the Atherosclerosis Risk in Communities (ARIC) Study

por Juraschek, Stephen P., Shantha, Ghanshyam Palamaner Subash, Chu, Audrey Y., Miller, Edgar R., Guallar, Eliseo, Hoogeveen, Ron C., Ballantyne, Christie M., Brancati, Frederick L., Schmidt, Maria Inês, Pankow, James S., Young, J. Hunter
Publicado 2013

A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans

por Clapham, Katharine R., Chu, Audrey Y., Wessel, Jennifer, Natarajan, Pradeep, Flannick, Jason, Rivas, Manuel A., Sartori, Samantha, Mehran, Roxana, Baber, Usman, Fuster, Valentin, Scott, Robert A., Rader, Daniel J., Boehnke, Michael, McCarthy, Mark I., Altshuler, David M., Kathiresan, Sekar, Peloso, Gina M.
Publicado 2016

Epigenome-wide association studies identify DNA methylation associated with kidney function

por Chu, Audrey Y., Tin, Adrienne, Schlosser, Pascal, Ko, Yi-An, Qiu, Chengxiang, Yao, Chen, Joehanes, Roby, Grams, Morgan E., Liang, Liming, Gluck, Caroline A., Liu, Chunyu, Coresh, Josef, Hwang, Shih-Jen, Levy, Daniel, Boerwinkle, Eric, Pankow, James S., Yang, Qiong, Fornage, Myriam, Fox, Caroline S., Susztak, Katalin, Köttgen, Anna
Publicado 2017

Fried food consumption, genetic risk, and body mass index: gene-diet interaction analysis in three US cohort studies

por Qi, Qibin, Chu, Audrey Y, Kang, Jae H, Huang, Jinyan, Rose, Lynda M, Jensen, Majken K, Liang, Liming, Curhan, Gary C, Pasquale, Louis R, Wiggs, Janey L, De Vivo, Immaculata, Chan, Andrew T, Choi, Hyon K, Tamimi, Rulla M, Ridker, Paul M, Hunter, David J, Willett, Walter C, Rimm, Eric B, Chasman, Daniel I, Hu, Frank B, Qi, Lu
Publicado 2014

Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study

por Cardona, Alexia, Day, Felix R., Perry, John R.B., Loh, Marie, Chu, Audrey Y., Lehne, Benjamin, Paul, Dirk S., Lotta, Luca A., Stewart, Isobel D., Kerrison, Nicola D., Scott, Robert A., Khaw, Kay-Tee, Forouhi, Nita G., Langenberg, Claudia, Liu, Chunyu, Mendelson, Michael M., Levy, Daniel, Beck, Stephan, Leslie, R. David, Dupuis, Josée, Meigs, James B., Kooner, Jaspal S., Pihlajamäki, Jussi, Vaag, Allan, Perfilyev, Alexander, Ling, Charlotte, Hivert, Marie-France, Chambers, John C., Wareham, Nicholas J., Ong, Ken K.
Publicado 2019

Genetic loci associated with circulating levels of very long-chain saturated fatty acids

por Lemaitre, Rozenn N., King, Irena B., Kabagambe, Edmond K., Wu, Jason H. Y., McKnight, Barbara, Manichaikul, Ani, Guan, Weihua, Sun, Qi, Chasman, Daniel I., Foy, Millennia, Wang, Lu, Zhu, Jingwen, Siscovick, David S., Tsai, Michael Y., Arnett, Donna K., Psaty, Bruce M., Djousse, Luc, Chen, Yii-Der I., Tang, Weihong, Weng, Lu-Chen, Wu, Hongyu, Jensen, Majken K., Chu, Audrey Y., Jacobs, David R., Rich, Stephen S., Mozaffarian, Dariush, Steffen, Lyn, Rimm, Eric B., Hu, Frank B., Ridker, Paul M., Fornage, Myriam, Friedlander, Yechiel
Publicado 2015

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions

por Shungin, Dmitry, Deng, Wei Q., Varga, Tibor V., Luan, Jian'an, Mihailov, Evelin, Metspalu, Andres, Morris, Andrew P., Forouhi, Nita G., Lindgren, Cecilia, Magnusson, Patrik K. E., Pedersen, Nancy L., Hallmans, Göran, Chu, Audrey Y., Justice, Anne E., Graff, Mariaelisa, Winkler, Thomas W., Rose, Lynda M., Langenberg, Claudia, Cupples, L. Adrienne, Ridker, Paul M., Wareham, Nicholas J., Ong, Ken K., Loos, Ruth J. F., Chasman, Daniel I., Ingelsson, Erik, Kilpeläinen, Tuomas O., Scott, Robert A., Mägi, Reedik, Paré, Guillaume, Franks, Paul W.
Publicado 2017

Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels

por Tin, Adrienne, Li, Yong, Brody, Jennifer A., Nutile, Teresa, Chu, Audrey Y., Huffman, Jennifer E., Yang, Qiong, Chen, Ming-Huei, Robinson-Cohen, Cassianne, Macé, Aurélien, Liu, Jun, Demirkan, Ayşe, Sorice, Rossella, Sedaghat, Sanaz, Swen, Melody, Yu, Bing, Ghasemi, Sahar, Teumer, Alexanda, Vollenweider, Peter, Ciullo, Marina, Li, Meng, Uitterlinden, André G., Kraaij, Robert, Amin, Najaf, van Rooij, Jeroen, Kutalik, Zoltán, Dehghan, Abbas, McKnight, Barbara, van Duijn, Cornelia M., Morrison, Alanna, Psaty, Bruce M., Boerwinkle, Eric, Fox, Caroline S., Woodward, Owen M., Köttgen, Anna
Publicado 2018

Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies

por Harlow, Charli E., Gandawijaya, Josan, Bamford, Rosemary A., Martin, Emily-Rose, Wood, Andrew R., van der Most, Peter J., Tanaka, Toshiko, Leonard, Hampton L., Etheridge, Amy S., Innocenti, Federico, Beaumont, Robin N., Tyrrell, Jessica, Nalls, Mike A., Simonsick, Eleanor M., Garimella, Pranav S., Shiroma, Eric J., Verweij, Niek, van der Meer, Peter, Gansevoort, Ron T., Snieder, Harold, Gallins, Paul J., Jima, Dereje D., Wright, Fred, Zhou, Yi-hui, Ferrucci, Luigi, Bandinelli, Stefania, Hernandez, Dena G., van der Harst, Pim, Patel, Vickas V., Waterworth, Dawn M., Chu, Audrey Y., Oguro-Ando, Asami, Frayling, Timothy M.
Publicado 2022

Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry

por Ahmad, Shafqat, Rukh, Gull, Varga, Tibor V., Ali, Ashfaq, Kurbasic, Azra, Shungin, Dmitry, Ericson, Ulrika, Koivula, Robert W., Chu, Audrey Y., Rose, Lynda M., Ganna, Andrea, Qi, Qibin, Stančáková, Alena, Sandholt, Camilla H., Elks, Cathy E., Curhan, Gary, Jensen, Majken K., Tamimi, Rulla M., Allin, Kristine H., Jørgensen, Torben, Brage, Soren, Langenberg, Claudia, Aadahl, Mette, Grarup, Niels, Linneberg, Allan, Paré, Guillaume, Magnusson, Patrik K. E., Pedersen, Nancy L., Boehnke, Michael, Hamsten, Anders, Mohlke, Karen L., Pasquale, Louis T., Pedersen, Oluf, Scott, Robert A., Ridker, Paul M., Ingelsson, Erik, Laakso, Markku, Hansen, Torben, Qi, Lu, Wareham, Nicholas J., Chasman, Daniel I., Hallmans, Göran, Hu, Frank B., Renström, Frida, Orho-Melander, Marju, Franks, Paul W.
Publicado 2013

Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts

por Mozaffarian, Dariush, Dashti, Hassan S, Wojczynski, Mary K, Chu, Audrey Y, Nettleton, Jennifer A, Männistö, Satu, Kristiansson, Kati, Reedik, Mägi, Lahti, Jari, Houston, Denise K, Cornelis, Marilyn C, van Rooij, Frank J. A, Dimitriou, Maria, Kanoni, Stavroula, Mikkilä, Vera, Steffen, Lyn M, de Oliveira Otto, Marcia C, Qi, Lu, Psaty, Bruce, Djousse, Luc, Rotter, Jerome I, Harald, Kennet, Perola, Markus, Rissanen, Harri, Jula, Antti, Krista, Fischer, Mihailov, Evelin, Feitosa, Mary F, Ngwa, Julius S, Xue, Luting, Jacques, Paul F, Perälä, Mia-Maria, Palotie, Aarno, Liu, Yongmei, Nalls, Nike A, Ferrucci, Luigi, Hernandez, Dena, Manichaikul, Ani, Tsai, Michael Y, Kiefte-de Jong, Jessica C, Hofman, Albert, Uitterlinden, André G, Rallidis, Loukianos, Ridker, Paul M, Rose, Lynda M, Buring, Julie E, Lehtimäki, Terho, Kähönen, Mika, Viikari, Jorma, Lemaitre, Rozenn, Salomaa, Veikko, Knekt, Paul, Metspalu, Andres, Borecki, Ingrid B, Cupples, L. Adrienne, Eriksson, Johan G, Kritchevsky, Stephen B, Bandinelli, Stefania, Siscovick, David, Franco, Oscar H, Deloukas, Panos, Dedoussis, George, Chasman, Daniel I, Raitakari, Olli, Tanaka, Toshiko
Publicado 2017

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

por Liu, Jun, Carnero-Montoro, Elena, van Dongen, Jenny, Lent, Samantha, Nedeljkovic, Ivana, Ligthart, Symen, Tsai, Pei-Chien, Martin, Tiphaine C., Mandaviya, Pooja R., Jansen, Rick, Peters, Marjolein J., Duijts, Liesbeth, Jaddoe, Vincent W. V., Tiemeier, Henning, Felix, Janine F., Willemsen, Gonneke, de Geus, Eco J. C., Chu, Audrey Y., Levy, Daniel, Hwang, Shih-Jen, Bressler, Jan, Gondalia, Rahul, Salfati, Elias L., Herder, Christian, Hidalgo, Bertha A., Tanaka, Toshiko, Moore, Ann Zenobia, Lemaitre, Rozenn N., Jhun, Min A, Smith, Jennifer A., Sotoodehnia, Nona, Bandinelli, Stefania, Ferrucci, Luigi, Arnett, Donna K., Grallert, Harald, Assimes, Themistocles L., Hou, Lifang, Baccarelli, Andrea, Whitsel, Eric A., van Dijk, Ko Willems, Amin, Najaf, Uitterlinden, André G., Sijbrands, Eric J. G., Franco, Oscar H., Dehghan, Abbas, Spector, Tim D., Dupuis, Josée, Hivert, Marie-France, Rotter, Jerome I., Meigs, James B., Pankow, James S., van Meurs, Joyce B. J., Isaacs, Aaron, Boomsma, Dorret I., Bell, Jordana T., Demirkan, Ayşe, van Duijn, Cornelia M.
Publicado 2019

Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake(1)(2)(3)(4)

por Tanaka, Toshiko, Ngwa, Julius S, van Rooij, Frank JA, Zillikens, M Carola, Wojczynski, Mary K, Frazier-Wood, Alexis C, Houston, Denise K, Kanoni, Stavroula, Lemaitre, Rozenn N, Luan, Jian'an, Mikkilä, Vera, Renstrom, Frida, Sonestedt, Emily, Zhao, Jing Hua, Chu, Audrey Y, Qi, Lu, Chasman, Daniel I, de Oliveira Otto, Marcia C, Dhurandhar, Emily J, Feitosa, Mary F, Johansson, Ingegerd, Khaw, Kay-Tee, Lohman, Kurt K, Manichaikul, Ani, McKeown, Nicola M, Mozaffarian, Dariush, Singleton, Andrew, Stirrups, Kathleen, Viikari, Jorma, Ye, Zheng, Bandinelli, Stefania, Barroso, Inês, Deloukas, Panos, Forouhi, Nita G, Hofman, Albert, Liu, Yongmei, Lyytikäinen, Leo-Pekka, North, Kari E, Dimitriou, Maria, Hallmans, Goran, Kähönen, Mika, Langenberg, Claudia, Ordovas, Jose M, Uitterlinden, André G, Hu, Frank B, Kalafati, Ioanna-Panagiota, Raitakari, Olli, Franco, Oscar H, Johnson, Andrew, Emilsson, Valur, Schrack, Jennifer A, Semba, Richard D, Siscovick, David S, Arnett, Donna K, Borecki, Ingrid B, Franks, Paul W, Kritchevsky, Stephen B, Lehtimäki, Terho, Loos, Ruth JF, Orho-Melander, Marju, Rotter, Jerome I, Wareham, Nicholas J, Witteman, Jacqueline CM, Ferrucci, Luigi, Dedoussis, George, Cupples, L Adrienne, Nettleton, Jennifer A
Publicado 2013

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

por Merino, Jordi, Guasch-Ferré, Marta, Ellervik, Christina, Dashti, Hassan S, Sharp, Stephen J, Wu, Peitao, Overvad, Kim, Sarnowski, Chloé, Kuokkanen, Mikko, Lemaitre, Rozenn N, Justice, Anne E, Ericson, Ulrika, Braun, Kim V E, Mahendran, Yuvaraj, Frazier-Wood, Alexis C, Sun, Dianjianyi, Chu, Audrey Y, Tanaka, Toshiko, Luan, Jian’an, Hong, Jaeyoung, Tjønneland, Anne, Ding, Ming, Lundqvist, Annamari, Mukamal, Kenneth, Rohde, Rebecca, Schulz, Christina-Alexandra, Franco, Oscar H, Grarup, Niels, Chen, Yii-Der Ida, Bazzano, Lydia, Franks, Paul W, Buring, Julie E, Langenberg, Claudia, Liu, Ching-Ti, Hansen, Torben, Jensen, Majken K, Sääksjärvi, Katri, Psaty, Bruce M, Young, Kristin L, Hindy, George, Sandholt, Camilla Helene, Ridker, Paul M, Ordovas, Jose M, Meigs, James B, Pedersen, Oluf, Kraft, Peter, Perola, Markus, North, Kari E, Orho-Melander, Marju, Voortman, Trudy, Toft, Ulla, Rotter, Jerome I, Qi, Lu, Forouhi, Nita G, Mozaffarian, Dariush, Sørensen, Thorkild I A, Stampfer, Meir J, Männistö, Satu, Selvin, Elizabeth, Imamura, Fumiaki, Salomaa, Veikko, Hu, Frank B, Wareham, Nick J, Dupuis, Josée, Smith, Caren E, Kilpeläinen, Tuomas O, Chasman, Daniel I, Florez, Jose C
Publicado 2019

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

por Ligthart, Symen, Marzi, Carola, Aslibekyan, Stella, Mendelson, Michael M., Conneely, Karen N., Tanaka, Toshiko, Colicino, Elena, Waite, Lindsay L., Joehanes, Roby, Guan, Weihua, Brody, Jennifer A., Elks, Cathy, Marioni, Riccardo, Jhun, Min A., Agha, Golareh, Bressler, Jan, Ward-Caviness, Cavin K., Chen, Brian H., Huan, Tianxiao, Bakulski, Kelly, Salfati, Elias L., Fiorito, Giovanni, Wahl, Simone, Schramm, Katharina, Sha, Jin, Hernandez, Dena G., Just, Allan C., Smith, Jennifer A., Sotoodehnia, Nona, Pilling, Luke C., Pankow, James S., Tsao, Phil S., Liu, Chunyu, Zhao, Wei, Guarrera, Simonetta, Michopoulos, Vasiliki J., Smith, Alicia K., Peters, Marjolein J., Melzer, David, Vokonas, Pantel, Fornage, Myriam, Prokisch, Holger, Bis, Joshua C., Chu, Audrey Y., Herder, Christian, Grallert, Harald, Yao, Chen, Shah, Sonia, McRae, Allan F., Lin, Honghuang, Horvath, Steve, Fallin, Daniele, Hofman, Albert, Wareham, Nicholas J., Wiggins, Kerri L., Feinberg, Andrew P., Starr, John M., Visscher, Peter M., Murabito, Joanne M., Kardia, Sharon L. R., Absher, Devin M., Binder, Elisabeth B., Singleton, Andrew B., Bandinelli, Stefania, Peters, Annette, Waldenberger, Melanie, Matullo, Giuseppe, Schwartz, Joel D., Demerath, Ellen W., Uitterlinden, André G., van Meurs, Joyce B. J., Franco, Oscar H., Chen, Yii-Der Ida, Levy, Daniel, Turner, Stephen T., Deary, Ian J., Ressler, Kerry J., Dupuis, Josée, Ferrucci, Luigi, Ong, Ken K., Assimes, Themistocles L., Boerwinkle, Eric, Koenig, Wolfgang, Arnett, Donna K., Baccarelli, Andrea A., Benjamin, Emelia J., Dehghan, Abbas
Publicado 2016