Optimized Replacement T4 and T4+T3 Dosing in Male and Female Hypothyroid Patients With Different BMIs Using a Personalized Mechanistic Model of Thyroid Hormone Regulation Dynamics

por Cruz-Loya, Mauricio, Chu, Benjamin B., Jonklaas, Jacqueline, Schneider, David F., DiStefano, Joseph
Publicado 2022

Multivariate genome-wide association analysis by iterative hard thresholding

por Chu, Benjamin B, Ko, Seyoon, Zhou, Jin J, Jensen, Aubrey, Zhou, Hua, Sinsheimer, Janet S, Lange, Kenneth
Publicado 2023

Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity

por Chu, Benjamin B, Keys, Kevin L, German, Christopher A, Zhou, Hua, Zhou, Jin J, Sobel, Eric M, Sinsheimer, Janet S, Lange, Kenneth
Publicado 2020

Unsupervised discovery of ancestry-informative markers and genetic admixture proportions in biobank-scale datasets

por Ko, Seyoon, Chu, Benjamin B., Peterson, Daniel, Okenwa, Chidera, Papp, Jeanette C., Alexander, David H., Sobel, Eric M., Zhou, Hua, Lange, Kenneth L.
Publicado 2023