Synthetic DNA delivery by electroporation promotes robust in vivo sulfation of broadly neutralizing anti-HIV immunoadhesin eCD4-Ig

por Xu, Ziyang, Wise, Megan C., Choi, Hyeree, Perales-Puchalt, Alfredo, Patel, Ami, Tello-Ruiz, Edgar, Chu, Jacqueline D., Muthumani, Kar, Weiner, David B.
Publicado 2018

Synthetic DNA Delivery of an Optimized and Engineered Monoclonal Antibody Provides Rapid and Prolonged Protection against Experimental Gonococcal Infection

por Parzych, Elizabeth M., Gulati, Sunita, Zheng, Bo, Bah, Mamadou A., Elliott, Sarah T. C., Chu, Jacqueline D., Nowak, Nancy, Reed, George W., Beurskens, Frank J., Schuurman, Janine, Rice, Peter A., Weiner, David B., Ram, Sanjay
Publicado 2021

Engineered DNA-encoded monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein confer single dose protection in a murine malaria challenge model

por Tursi, Nicholas J., Reeder, Sophia M., Flores-Garcia, Yevel, Bah, Mamadou A., Mathis-Torres, Shamika, Salgado-Jimenez, Berenice, Esquivel, Rianne, Xu, Ziyang, Chu, Jacqueline D., Humeau, Laurent, Patel, Ami, Zavala, Fidel, Weiner, David B.
Publicado 2022

DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2

por Parzych, Elizabeth M., Du, Jianqiu, Ali, Ali R., Schultheis, Katherine, Frase, Drew, Smith, Trevor R. F., Cui, Jiayan, Chokkalingam, Neethu, Tursi, Nicholas J., Andrade, Viviane M., Warner, Bryce M., Gary, Ebony N., Li, Yue, Choi, Jihae, Eisenhauer, Jillian, Maricic, Igor, Kulkarni, Abhijeet, Chu, Jacqueline D., Villafana, Gabrielle, Rosenthal, Kim, Ren, Kuishu, Francica, Joseph R., Wootton, Sarah K., Tebas, Pablo, Kobasa, Darwyn, Broderick, Kate E., Boyer, Jean D., Esser, Mark T., Pallesen, Jesper, Kulp, Dan W., Patel, Ami, Weiner, David B.
Publicado 2022