The potential for microRNA-based therapeutics in retinal disorders

por Chu-Tan, Joshua A., Natoli, Riccardo
Publicado 2020

Short exposure to photo-oxidative damage triggers molecular signals indicative of early retinal degeneration

por Wooff, Yvette, Cioanca, Adrian V., Wills, Elly, Chu-Tan, Joshua A., Sekar, Rakshanya, Natoli, Riccardo
Publicado 2023

Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration

por Natoli, Riccardo, Fernando, Nilisha, Madigan, Michele, Chu-Tan, Joshua A., Valter, Krisztina, Provis, Jan, Rutar, Matt
Publicado 2017

Small-Medium Extracellular Vesicles and Their miRNA Cargo in Retinal Health and Degeneration: Mediators of Homeostasis, and Vehicles for Targeted Gene Therapy

por Wooff, Yvette, Cioanca, Adrian V., Chu-Tan, Joshua A., Aggio-Bruce, Riemke, Schumann, Ulrike, Natoli, Riccardo
Publicado 2020

Inhibition of microRNA-155 Protects Retinal Function Through Attenuation of Inflammation in Retinal Degeneration

por Aggio-Bruce, Riemke, Chu-Tan, Joshua A., Wooff, Yvette, Cioanca, Adrian V., Schumann, Ulrike, Natoli, Riccardo
Publicado 2020

Voluntary exercise modulates pathways associated with amelioration of retinal degenerative diseases

por Chu-Tan, Joshua A., Cioanca, Adrian V., Wooff, Yvette, Kirkby, Max, Ellis, Marissa, Gulati, Pranay, Karl, Tim, Boatright, Jeffrey H., Bales, Katie, Nickerson, John, Natoli, Riccardo
Publicado 2023

A method for gene knockdown in the retina using a lipid-based carrier

por Chu-Tan, Joshua A., Fernando, Nilisha, Aggio-Bruce, Riemke, Cioanca, Adrian V., Valter, Krisztina, Andronikou, Nektaria, deMollerat du Jeu, Xavier, Rutar, Matt, Provis, Jan, Natoli, Riccardo
Publicado 2020

Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration

por Wooff, Yvette, Fernando, Nilisha, Wong, Josephine H. C., Dietrich, Catherine, Aggio-Bruce, Riemke, Chu-Tan, Joshua A., Robertson, Avril A. B., Doyle, Sarah L., Man, Si Ming, Natoli, Riccardo
Publicado 2020

Functional microRNA targetome undergoes degeneration-induced shift in the retina

por Chu-Tan, Joshua A., Cioanca, Adrian V., Feng, Zhi-Ping, Wooff, Yvette, Schumann, Ulrike, Aggio-Bruce, Riemke, Patel, Hardip, Rutar, Matt, Hannan, Katherine, Panov, Konstantin, Provis, Jan, Natoli, Riccardo
Publicado 2021

Obesity-induced metabolic disturbance drives oxidative stress and complement activation in the retinal environment

por Natoli, Riccardo, Fernando, Nilisha, Dahlenburg, Tess, Jiao, Haihan, Aggio-Bruce, Riemke, Barnett, Nigel L., Chao de la Barca, Juan Manuel, Tcherkez, Guillaume, Reynier, Pascal, Fang, Johnny, Chu-Tan, Joshua A., Valter, Krisztina, Provis, Jan, Rutar, Matt
Publicado 2018

Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration

por Zeng, Shaoxue, Zhang, Ting, Chen, Yingying, Chu-Tan, Joshua, Jin, Kaiyu, Lee, So-Ra, Yam, Michelle X, Madigan, Michele C, Fernando, Nilisha, Cioanca, Adrian, Zhou, Fanfan, Zhu, Meidong, Zhang, Junjun, Natoli, Riccardo, Fan, Xiaohui, Zhu, Ling, Gillies, Mark C
Publicado 2022

MicroRNA-223 Regulates Retinal Function and Inflammation in the Healthy and Degenerating Retina

por Fernando, Nilisha, Wong, Josephine H. C., Das, Shannon, Dietrich, Catherine, Aggio-Bruce, Riemke, Cioanca, Adrian V., Wooff, Yvette, Chu-Tan, Joshua A., Schumann, Ulrike, Ngo, Chinh, Essex, Rohan W., Dorian, Camilla, Robertson, Sarah A., Man, Si Ming, Provis, Jan, Natoli, Riccardo
Publicado 2020