Sirtuins: New Roles for Sirtuins in Aging and Disease

por Chua, Katrin
Publicado 2020

The Function of AID in Somatic Mutation and Class Switch Recombination: Upstream or Downstream of DNA Breaks

por Chua, Katrin F., Alt, Frederick W., Manis, John P.
Publicado 2002

Mammalian SIRT6 Represses Invasive Cancer Cell Phenotypes through ATP Citrate Lyase (ACLY)-Dependent Histone Acetylation

por Zheng, Wei, Tasselli, Luisa, Li, Tie-mei, Chua, Katrin F.
Publicado 2021

Structural basis for the activation and inhibition of Sirtuin 6 by quercetin and its derivatives

por You, Weijie, Zheng, Wei, Weiss, Sandra, Chua, Katrin F., Steegborn, Clemens
Publicado 2019

SIRT6 is required for maintenance of telomere position effect in human cells

por Tennen, Ruth I., Bua, Dennis J., Wright, Woodring E., Chua, Katrin F.
Publicado 2011

Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient β-catenin degradation

por Li, Tie-Mei, Ren, Jing, Husmann, Dylan, Coan, John P., Gozani, Or, Chua, Katrin F.
Publicado 2020

SIRT6 deacetylates H3K18Ac at pericentric chromatin to prevent mitotic errors and cell senescence

por Tasselli, Luisa, Xi, Yuanxin, Zheng, Wei, Tennen, Ruth I., Odrowaz, Zaneta, Simeoni, Federica, Li, Wei, Chua, Katrin F.
Publicado 2016

Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules

por Li, Tie-Mei, Coan, John P., Krajewski, Krzysztof, Zhang, Lichao, Elias, Joshua E., Strahl, Brian D., Gozani, Or, Chua, Katrin F.
Publicado 2019

SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

por Malik, Shivani, Villanova, Lidia, Tanaka, Shinji, Aonuma, Misato, Roy, Nilotpal, Berber, Elisabeth, Pollack, Jonathan R., Michishita-Kioi, Eriko, Chua, Katrin F.
Publicado 2015

Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling

por Simeoni, Federica, Tasselli, Luisa, Tanaka, Shinji, Villanova, Lidia, Hayashi, Mayumi, Kubota, Kazuishi, Isono, Fujio, Garcia, Benjamin A., Michishita-Kioi, Eriko, Chua, Katrin F.
Publicado 2013

Antibody toolkit to investigate eEF1A methylation dynamics in mRNA translation elongation

por Mealey-Farr, Robert, Jeong, Jinho, Park, Juhyung, Liu, Shuo, Hausmann, Simone, Francis, Joel W., Angulo Ibanez, Maria, Cho, Joonseok, Chua, Katrin, Mazur, Pawel K., Gozani, Or
Publicado 2023

SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair

por McCord, Ronald A., Michishita, Eriko, Hong, Tao, Berber, Elisabeth, Boxer, Lisa D., Kusumoto, Rika, Guan, Shenheng, Shi, Xiaobing, Gozani, Or, Burlingame, Alma L., Bohr, Vilhelm A., Chua, Katrin F.
Publicado 2009

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

por Barber, Matthew F., Michishita-Kioi, Eriko, Xi, Yuanxin, Tasselli, Luisa, Kioi, Mitomu, Moqtaderi, Zarmik, Tennen, Ruth I., Paredes, Silvana, Young, Nicolas L., Chen, Kaifu, Struhl, Kevin, Garcia, Benjamin A., Gozani, Or, Li, Wei, Chua, Katrin F.
Publicado 2012

Elevated NSD3 Histone Methylation Activity Drives Squamous Cell Lung Cancer

por Yuan, Gang, Flores, Natasha M., Hausmann, Simone, Lofgren, Shane M., Kharchenko, Vladlena, Angulo-Ibanez, Maria, Sengupta, Deepanwita, Lu, Xiaoyin, Czaban, Iwona, Azhibek, Dulat, Vicent, Silvestre, Fischle, Wolfgang, Jaremko, Mariusz, Fang, Bingliang, Wistuba, Ignacio I., Chua, Katrin F., Roth, Jack A., Minna, John D., Shao, Ning-Yi, Jaremko, Łukasz, Mazur, Pawel K., Gozani, Or
Publicado 2021

SETD6 lysine methylation of RelA couples GLP activity at chromatin to tonic repression of NF-κB signaling

por Levy, Dan, Kuo, Alex J., Chang, Yanqi, Schaefer, Uwe, Kitson, Christopher, Cheung, Peggie, Espejo, Alexsandra, Zee, Barry M., Liu, Chih Long, Tangsombatvisit, Stephanie, Tennen, Ruth I., Kuo, Andrew Y., Tanjing, Song, Cheung, Regina, Chua, Katrin F., Utz, Paul J., Shi, Xiaobing, Prinjha, Rab K., Lee, Kevin, Garcia, Benjamin A., Bedford, Mark T., Tarakhovsky, Alexander, Cheng, Xiaodong, Gozani, Or
Publicado 2010