Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer

por Christin, John R., Wang, Chunhui, Chung, Chi-Yeh, Liu, Yu, Dravis, Christopher, Tang, Wei, Oktay, Maja H., Wahl, Geoffrey M., Guo, Wenjun
Publicado 2020

Intrinsic and acquired drug resistance to LSD1 inhibitors in small cell lung cancer occurs through a TEAD4‐driven transcriptional state

por Yan, Wen, Chung, Chi‐Yeh, Xie, Tao, Ozeck, Mark, Nichols, Timothy C., Frey, Jessica, Udyavar, Akshata R., Sharma, Shikhar, Paul, Thomas A.
Publicado 2021

Targeted interference of SIN3A-TGIF1 function by SID decoy treatment inhibits Wnt signaling and invasion in triple negative breast cancer cells

por Kwon, Yeon-Jin, Leibovitch, Boris A., Bansal, Nidhi, Pereira, Lutecia, Chung, Chi-Yeh, Ariztia, Edgardo V., Zelent, Arthur, Farias, Eduardo F., Waxman, Samuel
Publicado 2016

Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage Relationships

por Chung, Chi-Yeh, Ma, Zhibo, Dravis, Christopher, Preissl, Sebastian, Poirion, Olivier, Luna, Gidsela, Hou, Xiaomeng, Giraddi, Rajshekhar R., Ren, Bing, Wahl, Geoffrey M.
Publicado 2019

Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis

por DelGiorno, Kathleen E., Naeem, Razia F., Fang, Linjing, Chung, Chi-Yeh, Ramos, Cynthia, Luhtala, Natalie, O’Connor, Carolyn, Hunter, Tony, Manor, Uri, Wahl, Geoffrey M.
Publicado 2020

NR2F1 controls tumor cell dormancy via SOX9 and RARβ driven quiescence programs

por Sosa, Maria Soledad, Parikh, Falguni, Maia, Alexandre Gaspar, Estrada, Yeriel, Bosch, Almudena, Bragado, Paloma, Ekpin, Esther, George, Ajish, Zheng, Yang, Lam, Hung-Ming, Morrissey, Colm, Chung, Chi-Yeh, Farias, Eduardo F., Bernstein, Emily, Aguirre-Ghiso, Julio A.
Publicado 2015

Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer

por Bansal, Nidhi, Petrie, Kevin, Christova, Rossitza, Chung, Chi-Yeh, Leibovitch, Boris A., Howell, Louise, Gil, Veronica, Sbirkov, Yordan, Lee, EunJee, Wexler, Joanna, Ariztia, Edgardo V., Sharma, Rajal, Zhu, Jun, Bernstein, Emily, Zhou, Ming-Ming, Zelent, Arthur, Farias, Eduardo, Waxman, Samuel
Publicado 2015

PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor, Talazoparib

por Ding, Xia, Zhu, Zhou, Lapek, John, McMillan, Elizabeth A., Zhang, Alexander, Chung, Chi-Yeh, Dubbury, Sara, Lapira, Jennifer, Firdaus, Sarah, Kang, Xiaolin, Gao, Jingjin, Oyer, Jon, Chionis, John, Rollins, Robert A., Li, Lianjie, Niessen, Sherry, Bagrodia, Shubha, Zhang, Lianglin, VanArsdale, Todd
Publicado 2022

Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development

por Giraddi, Rajshekhar R., Chung, Chi-Yeh, Heinz, Richard E., Balcioglu, Ozlen, Novotny, Mark, Trejo, Christy L., Dravis, Christopher, Hagos, Berhane M., Mehrabad, Elnaz Mirzaei, Rodewald, Luo Wei, Hwang, Jae Y., Fan, Cheng, Lasken, Roger, Varley, Katherine E., Perou, Charles M., Wahl, Geoffrey M., Spike, Benjamin T.
Publicado 2018

MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming

por Mohammed Ismail, Wazim, Mazzone, Amelia, Ghiraldini, Flavia G., Kaur, Jagneet, Bains, Manvir, Munankarmy, Amik, Bagwell, Monique S., Safgren, Stephanie L., Moore-Weiss, John, Buciuc, Marina, Shimp, Lynzie, Leach, Kelsey A., Duarte, Luis F., Nagi, Chandandeep S., Carcamo, Saul, Chung, Chi-Yeh, Hasson, Dan, Dadgar, Neda, Zhong, Jian, Lee, Jeong-Heon, Couch, Fergus J., Revzin, Alexander, Ordog, Tamas, Bernstein, Emily, Gaspar-Maia, Alexandre
Publicado 2023